Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.66888714 |
| Normalized Enrichment Score (NES) | 1.7419686 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04173994 |
| FWER p-Value | 0.18 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 10 | 4.988 | 0.0296 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 19 | 4.971 | 0.0591 | Yes |
| 3 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 47 | 4.882 | 0.0875 | Yes |
| 4 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 51 | 4.875 | 0.1166 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 54 | 4.870 | 0.1457 | Yes |
| 6 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 105 | 4.608 | 0.1719 | Yes |
| 7 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 140 | 4.434 | 0.1975 | Yes |
| 8 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 142 | 4.425 | 0.2239 | Yes |
| 9 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 207 | 4.163 | 0.2471 | Yes |
| 10 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 217 | 4.103 | 0.2713 | Yes |
| 11 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 252 | 3.978 | 0.2942 | Yes |
| 12 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 263 | 3.952 | 0.3176 | Yes |
| 13 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 270 | 3.926 | 0.3409 | Yes |
| 14 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 282 | 3.883 | 0.3638 | Yes |
| 15 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 301 | 3.811 | 0.3861 | Yes |
| 16 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 326 | 3.698 | 0.4076 | Yes |
| 17 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 361 | 3.577 | 0.4281 | Yes |
| 18 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 365 | 3.555 | 0.4492 | Yes |
| 19 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 371 | 3.546 | 0.4703 | Yes |
| 20 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 484 | 3.259 | 0.4868 | Yes |
| 21 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 488 | 3.237 | 0.5060 | Yes |
| 22 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 497 | 3.222 | 0.5251 | Yes |
| 23 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 501 | 3.205 | 0.5442 | Yes |
| 24 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 524 | 3.121 | 0.5622 | Yes |
| 25 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 569 | 3.069 | 0.5794 | Yes |
| 26 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 635 | 2.926 | 0.5951 | Yes |
| 27 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 875 | 2.551 | 0.6039 | Yes |
| 28 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 1304 | 1.950 | 0.6040 | Yes |
| 29 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 1375 | 1.873 | 0.6133 | Yes |
| 30 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 1382 | 1.858 | 0.6243 | Yes |
| 31 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 1658 | 1.688 | 0.6269 | Yes |
| 32 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1782 | 1.584 | 0.6331 | Yes |
| 33 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1962 | 1.462 | 0.6370 | Yes |
| 34 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 2108 | 1.359 | 0.6412 | Yes |
| 35 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 2300 | 1.239 | 0.6434 | Yes |
| 36 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2415 | 1.168 | 0.6473 | Yes |
| 37 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 2527 | 1.129 | 0.6511 | Yes |
| 38 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2591 | 1.095 | 0.6559 | Yes |
| 39 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 2690 | 1.039 | 0.6595 | Yes |
| 40 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 2777 | 0.997 | 0.6631 | Yes |
| 41 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 2784 | 0.993 | 0.6689 | Yes |
| 42 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 3294 | 0.784 | 0.6598 | No |
| 43 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3718 | 0.628 | 0.6521 | No |
| 44 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 3879 | 0.572 | 0.6512 | No |
| 45 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 4611 | 0.337 | 0.6335 | No |
| 46 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 5129 | 0.194 | 0.6206 | No |
| 47 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 5158 | 0.184 | 0.6210 | No |
| 48 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6207 | 0.000 | 0.5926 | No |
| 49 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6658 | 0.000 | 0.5804 | No |
| 50 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6995 | 0.000 | 0.5714 | No |
| 51 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8963 | 0.000 | 0.5181 | No |
| 52 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 9150 | 0.000 | 0.5131 | No |
| 53 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9531 | 0.000 | 0.5028 | No |
| 54 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9741 | 0.000 | 0.4972 | No |
| 55 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9811 | 0.000 | 0.4953 | No |
| 56 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9817 | 0.000 | 0.4952 | No |
| 57 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9963 | 0.000 | 0.4913 | No |
| 58 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10462 | 0.000 | 0.4778 | No |
| 59 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10997 | 0.000 | 0.4633 | No |
| 60 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12204 | 0.000 | 0.4307 | No |
| 61 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12315 | 0.000 | 0.4277 | No |
| 62 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12319 | 0.000 | 0.4276 | No |
| 63 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12349 | 0.000 | 0.4269 | No |
| 64 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12384 | 0.000 | 0.4259 | No |
| 65 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12965 | 0.000 | 0.4103 | No |
| 66 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13755 | 0.000 | 0.3889 | No |
| 67 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14556 | 0.000 | 0.3673 | No |
| 68 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 15413 | 0.000 | 0.3441 | No |
| 69 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15519 | 0.000 | 0.3413 | No |
| 70 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15646 | 0.000 | 0.3379 | No |
| 71 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 15650 | 0.000 | 0.3378 | No |
| 72 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16091 | 0.000 | 0.3259 | No |
| 73 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16122 | 0.000 | 0.3251 | No |
| 74 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16169 | 0.000 | 0.3238 | No |
| 75 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16431 | 0.000 | 0.3168 | No |
| 76 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16441 | 0.000 | 0.3165 | No |
| 77 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17101 | 0.000 | 0.2987 | No |
| 78 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17759 | 0.000 | 0.2809 | No |
| 79 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 17760 | 0.000 | 0.2809 | No |
| 80 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18377 | 0.000 | 0.2643 | No |
| 81 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18396 | 0.000 | 0.2638 | No |
| 82 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 18406 | 0.000 | 0.2635 | No |
| 83 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18427 | 0.000 | 0.2630 | No |
| 84 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18849 | 0.000 | 0.2516 | No |
| 85 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18871 | 0.000 | 0.2510 | No |
| 86 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18896 | 0.000 | 0.2504 | No |
| 87 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19465 | 0.000 | 0.2350 | No |
| 88 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 20416 | 0.000 | 0.2093 | No |
| 89 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 20452 | 0.000 | 0.2084 | No |
| 90 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 20543 | 0.000 | 0.2059 | No |
| 91 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20701 | 0.000 | 0.2017 | No |
| 92 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 21432 | 0.000 | 0.1819 | No |
| 93 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 22138 | 0.000 | 0.1629 | No |
| 94 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 22147 | 0.000 | 0.1626 | No |
| 95 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 22714 | 0.000 | 0.1473 | No |
| 96 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 22715 | 0.000 | 0.1473 | No |
| 97 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 23005 | 0.000 | 0.1395 | No |
| 98 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 23967 | 0.000 | 0.1135 | No |
| 99 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 25338 | 0.000 | 0.0765 | No |
| 100 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 25540 | 0.000 | 0.0710 | No |
| 101 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 27327 | 0.000 | 0.0227 | No |
| 102 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27832 | 0.000 | 0.0091 | No |
| 103 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 27900 | 0.000 | 0.0073 | No |
| 104 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 27918 | 0.000 | 0.0068 | No |
| 105 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 27929 | 0.000 | 0.0065 | No |
| 106 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 28613 | -0.130 | -0.0112 | No |
| 107 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 29266 | -0.302 | -0.0270 | No |
| 108 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 29512 | -0.367 | -0.0314 | No |
| 109 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 31063 | -0.771 | -0.0688 | No |
| 110 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 31095 | -0.780 | -0.0649 | No |
| 111 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 31236 | -0.825 | -0.0638 | No |
| 112 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 31357 | -0.852 | -0.0619 | No |
| 113 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 32190 | -1.127 | -0.0777 | No |
| 114 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32214 | -1.134 | -0.0716 | No |
| 115 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32684 | -1.319 | -0.0763 | No |
| 116 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 33179 | -1.529 | -0.0806 | No |
| 117 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 34538 | -2.114 | -0.1047 | No |
| 118 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 34601 | -2.149 | -0.0935 | No |
| 119 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35032 | -2.384 | -0.0909 | No |
| 120 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 35824 | -3.007 | -0.0943 | No |
| 121 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 35847 | -3.028 | -0.0768 | No |
| 122 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 36123 | -3.318 | -0.0644 | No |
| 123 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36431 | -3.627 | -0.0510 | No |
| 124 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 36474 | -3.681 | -0.0301 | No |
| 125 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36593 | -3.851 | -0.0103 | No |
| 126 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36689 | -3.962 | 0.0108 | No |
