Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.7656768 |
| Normalized Enrichment Score (NES) | 1.8628393 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0064827283 |
| FWER p-Value | 0.017 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 11 | 4.984 | 0.0445 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 16 | 4.973 | 0.0891 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.953 | 0.1332 | Yes |
| 4 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 33 | 4.951 | 0.1777 | Yes |
| 5 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 46 | 4.888 | 0.2213 | Yes |
| 6 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 79 | 4.762 | 0.2633 | Yes |
| 7 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 85 | 4.742 | 0.3057 | Yes |
| 8 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.3470 | Yes |
| 9 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 208 | 4.153 | 0.3815 | Yes |
| 10 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 236 | 4.050 | 0.4172 | Yes |
| 11 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 251 | 3.979 | 0.4525 | Yes |
| 12 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 289 | 3.842 | 0.4861 | Yes |
| 13 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 396 | 3.466 | 0.5144 | Yes |
| 14 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 501 | 3.205 | 0.5404 | Yes |
| 15 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 561 | 3.092 | 0.5666 | Yes |
| 16 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 596 | 3.001 | 0.5926 | Yes |
| 17 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 630 | 2.942 | 0.6182 | Yes |
| 18 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 1111 | 2.181 | 0.6248 | Yes |
| 19 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 1120 | 2.163 | 0.6440 | Yes |
| 20 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 1170 | 2.118 | 0.6618 | Yes |
| 21 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 1281 | 1.973 | 0.6765 | Yes |
| 22 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1297 | 1.962 | 0.6937 | Yes |
| 23 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1313 | 1.940 | 0.7108 | Yes |
| 24 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 1396 | 1.842 | 0.7251 | Yes |
| 25 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1416 | 1.818 | 0.7410 | Yes |
| 26 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 1985 | 1.438 | 0.7385 | Yes |
| 27 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 2048 | 1.393 | 0.7494 | Yes |
| 28 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 2254 | 1.262 | 0.7552 | Yes |
| 29 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2415 | 1.168 | 0.7614 | Yes |
| 30 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 2707 | 1.028 | 0.7627 | Yes |
| 31 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 2969 | 0.907 | 0.7638 | Yes |
| 32 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 3378 | 0.750 | 0.7596 | Yes |
| 33 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 3399 | 0.741 | 0.7657 | Yes |
| 34 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 3824 | 0.594 | 0.7596 | No |
| 35 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 4738 | 0.303 | 0.7376 | No |
| 36 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6184 | 0.000 | 0.6986 | No |
| 37 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6185 | 0.000 | 0.6986 | No |
| 38 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6206 | 0.000 | 0.6980 | No |
| 39 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6207 | 0.000 | 0.6980 | No |
| 40 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6209 | 0.000 | 0.6980 | No |
| 41 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6216 | 0.000 | 0.6978 | No |
| 42 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6218 | 0.000 | 0.6978 | No |
| 43 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6220 | 0.000 | 0.6978 | No |
| 44 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 6411 | 0.000 | 0.6927 | No |
| 45 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8424 | 0.000 | 0.6383 | No |
| 46 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 9098 | 0.000 | 0.6201 | No |
| 47 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 9127 | 0.000 | 0.6194 | No |
| 48 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10643 | 0.000 | 0.5784 | No |
| 49 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11646 | 0.000 | 0.5513 | No |
| 50 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15524 | 0.000 | 0.4466 | No |
| 51 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15797 | 0.000 | 0.4392 | No |
| 52 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16010 | 0.000 | 0.4335 | No |
| 53 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 16655 | 0.000 | 0.4161 | No |
| 54 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16695 | 0.000 | 0.4151 | No |
| 55 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17086 | 0.000 | 0.4045 | No |
| 56 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17685 | 0.000 | 0.3884 | No |
| 57 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17935 | 0.000 | 0.3816 | No |
| 58 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18627 | 0.000 | 0.3630 | No |
| 59 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18877 | 0.000 | 0.3562 | No |
| 60 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18917 | 0.000 | 0.3552 | No |
| 61 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18918 | 0.000 | 0.3552 | No |
| 62 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19341 | 0.000 | 0.3438 | No |
| 63 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19383 | 0.000 | 0.3427 | No |
| 64 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19463 | 0.000 | 0.3405 | No |
| 65 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19465 | 0.000 | 0.3405 | No |
| 66 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19468 | 0.000 | 0.3405 | No |
| 67 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19477 | 0.000 | 0.3402 | No |
| 68 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19480 | 0.000 | 0.3402 | No |
| 69 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19482 | 0.000 | 0.3402 | No |
| 70 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 20086 | 0.000 | 0.3239 | No |
| 71 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 26976 | 0.000 | 0.1377 | No |
| 72 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27830 | 0.000 | 0.1147 | No |
| 73 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27832 | 0.000 | 0.1147 | No |
| 74 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | 0.1145 | No |
| 75 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 28546 | -0.108 | 0.0964 | No |
| 76 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 29358 | -0.324 | 0.0774 | No |
| 77 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 33126 | -1.518 | -0.0108 | No |
| 78 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34848 | -2.313 | -0.0365 | No |
| 79 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 35311 | -2.596 | -0.0256 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 36248 | -3.450 | -0.0199 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37034 | -4.741 | 0.0015 | No |
