Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_SEROTONIN_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.81457084 |
| Normalized Enrichment Score (NES) | -1.5295327 |
| Nominal p-value | 0.0040871934 |
| FDR q-value | 0.41444513 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 4382 | 0.400 | -0.0625 | No |
| 2 | OR6T1 | olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848] | 14304 | 0.000 | -0.3303 | No |
| 3 | OR5T3 | olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297] | 14776 | 0.000 | -0.3430 | No |
| 4 | OR5T2 | olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296] | 14778 | 0.000 | -0.3430 | No |
| 5 | HTR4 | 5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299] | 15415 | 0.000 | -0.3602 | No |
| 6 | HTR6 | 5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301] | 15417 | 0.000 | -0.3602 | No |
| 7 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 15418 | 0.000 | -0.3602 | No |
| 8 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15482 | 0.000 | -0.3619 | No |
| 9 | HTR1F | 5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292] | 15484 | 0.000 | -0.3619 | No |
| 10 | HTR1D | 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] | 15485 | 0.000 | -0.3619 | No |
| 11 | HTR1A | 5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286] | 15486 | 0.000 | -0.3619 | No |
| 12 | HTR2B | 5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294] | 15493 | 0.000 | -0.3621 | No |
| 13 | HTR2C | 5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295] | 15494 | 0.000 | -0.3621 | No |
| 14 | HTR2A | 5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293] | 15495 | 0.000 | -0.3621 | No |
| 15 | HTR3E | 5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005] | 15500 | 0.000 | -0.3622 | No |
| 16 | HTR3C | 5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003] | 15501 | 0.000 | -0.3622 | No |
| 17 | HTR3D | 5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004] | 15502 | 0.000 | -0.3622 | No |
| 18 | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 15503 | 0.000 | -0.3622 | No |
| 19 | HTR3B | 5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298] | 15504 | 0.000 | -0.3622 | No |
| 20 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15515 | 0.000 | -0.3625 | No |
| 21 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17793 | 0.000 | -0.4239 | No |
| 22 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17795 | 0.000 | -0.4240 | No |
| 23 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17796 | 0.000 | -0.4240 | No |
| 24 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18469 | 0.000 | -0.4421 | No |
| 25 | OR10J5 | olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993] | 22943 | 0.000 | -0.5628 | No |
| 26 | OR10H1 | olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172] | 22967 | 0.000 | -0.5634 | No |
| 27 | OR10H3 | olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174] | 22968 | 0.000 | -0.5634 | No |
| 28 | OR10H2 | olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173] | 22969 | 0.000 | -0.5634 | No |
| 29 | OR10H5 | olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389] | 22970 | 0.000 | -0.5634 | No |
| 30 | OR10H4 | olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388] | 22971 | 0.000 | -0.5634 | No |
| 31 | OR11H4 | olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347] | 23200 | 0.000 | -0.5696 | No |
| 32 | OR11H7 | olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350] | 23209 | 0.000 | -0.5698 | No |
| 33 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 24006 | 0.000 | -0.5913 | No |
| 34 | HRH2 | histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183] | 24008 | 0.000 | -0.5913 | No |
| 35 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 24011 | 0.000 | -0.5914 | No |
| 36 | OR10J6P | olfactory receptor family 10 subfamily J member 6 pseudogene [Source:HGNC Symbol;Acc:HGNC:14994] | 24331 | 0.000 | -0.6000 | No |
| 37 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 29429 | -0.342 | -0.6899 | Yes |
| 38 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 34049 | -1.856 | -0.5563 | Yes |
| 39 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 36979 | -4.585 | 0.0030 | Yes |
