Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.7877436 |
| Normalized Enrichment Score (NES) | -1.5588096 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.28301024 |
| FWER p-Value | 0.981 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 4039 | 0.523 | -0.0751 | No |
| 2 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 4119 | 0.496 | -0.0449 | No |
| 3 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 9110 | 0.000 | -0.1796 | No |
| 4 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 9121 | 0.000 | -0.1799 | No |
| 5 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 9140 | 0.000 | -0.1804 | No |
| 6 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 9142 | 0.000 | -0.1804 | No |
| 7 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 9844 | 0.000 | -0.1994 | No |
| 8 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9848 | 0.000 | -0.1994 | No |
| 9 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10231 | 0.000 | -0.2098 | No |
| 10 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10235 | 0.000 | -0.2098 | No |
| 11 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12819 | 0.000 | -0.2796 | No |
| 12 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12823 | 0.000 | -0.2797 | No |
| 13 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13089 | 0.000 | -0.2868 | No |
| 14 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17257 | 0.000 | -0.3994 | No |
| 15 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17781 | 0.000 | -0.4135 | No |
| 16 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17782 | 0.000 | -0.4135 | No |
| 17 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17783 | 0.000 | -0.4135 | No |
| 18 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17793 | 0.000 | -0.4137 | No |
| 19 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17795 | 0.000 | -0.4138 | No |
| 20 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17796 | 0.000 | -0.4138 | No |
| 21 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17907 | 0.000 | -0.4167 | No |
| 22 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18465 | 0.000 | -0.4318 | No |
| 23 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18466 | 0.000 | -0.4318 | No |
| 24 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18468 | 0.000 | -0.4318 | No |
| 25 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18469 | 0.000 | -0.4318 | No |
| 26 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18470 | 0.000 | -0.4318 | No |
| 27 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19808 | 0.000 | -0.4679 | No |
| 28 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19912 | 0.000 | -0.4707 | No |
| 29 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19913 | 0.000 | -0.4707 | No |
| 30 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19960 | 0.000 | -0.4719 | No |
| 31 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19961 | 0.000 | -0.4719 | No |
| 32 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 20004 | 0.000 | -0.4731 | No |
| 33 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 20005 | 0.000 | -0.4731 | No |
| 34 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 20006 | 0.000 | -0.4731 | No |
| 35 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 20007 | 0.000 | -0.4731 | No |
| 36 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 20008 | 0.000 | -0.4731 | No |
| 37 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 20009 | 0.000 | -0.4731 | No |
| 38 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 21818 | 0.000 | -0.5219 | No |
| 39 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 21840 | 0.000 | -0.5225 | No |
| 40 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 21843 | 0.000 | -0.5225 | No |
| 41 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 21844 | 0.000 | -0.5225 | No |
| 42 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 21845 | 0.000 | -0.5225 | No |
| 43 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 21847 | 0.000 | -0.5225 | No |
| 44 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 21850 | 0.000 | -0.5226 | No |
| 45 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21853 | 0.000 | -0.5226 | No |
| 46 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 22345 | 0.000 | -0.5359 | No |
| 47 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 22346 | 0.000 | -0.5359 | No |
| 48 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 22347 | 0.000 | -0.5359 | No |
| 49 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 22348 | 0.000 | -0.5359 | No |
| 50 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 24006 | 0.000 | -0.5807 | No |
| 51 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 24011 | 0.000 | -0.5808 | No |
| 52 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 24787 | 0.000 | -0.6017 | No |
| 53 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 26741 | 0.000 | -0.6544 | No |
| 54 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 27158 | 0.000 | -0.6657 | No |
| 55 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 29041 | -0.243 | -0.7007 | Yes |
| 56 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 29429 | -0.342 | -0.6888 | Yes |
| 57 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 33092 | -1.503 | -0.6899 | Yes |
| 58 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 33858 | -1.756 | -0.5963 | Yes |
| 59 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 34049 | -1.856 | -0.4807 | Yes |
| 60 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 34377 | -2.016 | -0.3583 | Yes |
| 61 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 35621 | -2.873 | -0.2050 | Yes |
| 62 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 36530 | -3.759 | 0.0151 | Yes |
