Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.6123278 |
| Normalized Enrichment Score (NES) | -1.3109539 |
| Nominal p-value | 0.023569023 |
| FDR q-value | 0.26279694 |
| FWER p-Value | 0.975 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 63 | 4.848 | 0.0294 | No |
| 2 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 93 | 4.716 | 0.0588 | No |
| 3 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 308 | 3.777 | 0.0772 | No |
| 4 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 716 | 2.759 | 0.0839 | No |
| 5 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 738 | 2.720 | 0.1008 | No |
| 6 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 1324 | 1.926 | 0.0973 | No |
| 7 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 1327 | 1.922 | 0.1095 | No |
| 8 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 2181 | 1.308 | 0.0948 | No |
| 9 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 2306 | 1.236 | 0.0994 | No |
| 10 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 3058 | 0.867 | 0.0846 | No |
| 11 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 3114 | 0.863 | 0.0887 | No |
| 12 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 3326 | 0.771 | 0.0879 | No |
| 13 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 3379 | 0.750 | 0.0913 | No |
| 14 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 3770 | 0.612 | 0.0847 | No |
| 15 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 3883 | 0.572 | 0.0853 | No |
| 16 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 4422 | 0.389 | 0.0733 | No |
| 17 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 4743 | 0.302 | 0.0665 | No |
| 18 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 4753 | 0.299 | 0.0682 | No |
| 19 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 4908 | 0.259 | 0.0657 | No |
| 20 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 5019 | 0.223 | 0.0642 | No |
| 21 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 5091 | 0.202 | 0.0635 | No |
| 22 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 5219 | 0.166 | 0.0612 | No |
| 23 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 5586 | 0.153 | 0.0523 | No |
| 24 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 5732 | 0.127 | 0.0491 | No |
| 25 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 5810 | 0.100 | 0.0477 | No |
| 26 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 6089 | 0.017 | 0.0403 | No |
| 27 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 6495 | 0.000 | 0.0293 | No |
| 28 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 6769 | 0.000 | 0.0220 | No |
| 29 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 7138 | 0.000 | 0.0120 | No |
| 30 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7636 | 0.000 | -0.0014 | No |
| 31 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 7775 | 0.000 | -0.0052 | No |
| 32 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9000 | 0.000 | -0.0383 | No |
| 33 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 9353 | 0.000 | -0.0478 | No |
| 34 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10211 | 0.000 | -0.0710 | No |
| 35 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11154 | 0.000 | -0.0965 | No |
| 36 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11418 | 0.000 | -0.1036 | No |
| 37 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12771 | 0.000 | -0.1402 | No |
| 38 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13081 | 0.000 | -0.1485 | No |
| 39 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13248 | 0.000 | -0.1530 | No |
| 40 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 13396 | 0.000 | -0.1570 | No |
| 41 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 13855 | 0.000 | -0.1694 | No |
| 42 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14220 | 0.000 | -0.1792 | No |
| 43 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 15254 | 0.000 | -0.2072 | No |
| 44 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15777 | 0.000 | -0.2213 | No |
| 45 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15785 | 0.000 | -0.2215 | No |
| 46 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16176 | 0.000 | -0.2320 | No |
| 47 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 17509 | 0.000 | -0.2681 | No |
| 48 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17874 | 0.000 | -0.2779 | No |
| 49 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17892 | 0.000 | -0.2784 | No |
| 50 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18427 | 0.000 | -0.2928 | No |
| 51 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 20686 | 0.000 | -0.3539 | No |
| 52 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 22860 | 0.000 | -0.4127 | No |
| 53 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 23028 | 0.000 | -0.4172 | No |
| 54 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 23227 | 0.000 | -0.4226 | No |
| 55 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 24519 | 0.000 | -0.4575 | No |
| 56 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 26637 | 0.000 | -0.5148 | No |
| 57 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 27373 | 0.000 | -0.5347 | No |
| 58 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 27379 | 0.000 | -0.5348 | No |
| 59 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 27425 | 0.000 | -0.5360 | No |
| 60 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 27630 | 0.000 | -0.5415 | No |
| 61 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 28382 | -0.060 | -0.5615 | No |
| 62 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 28898 | -0.209 | -0.5740 | No |
| 63 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 29383 | -0.329 | -0.5850 | No |
| 64 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 29654 | -0.402 | -0.5898 | No |
| 65 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 29722 | -0.411 | -0.5889 | No |
| 66 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 29893 | -0.453 | -0.5906 | No |
| 67 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 29894 | -0.453 | -0.5877 | No |
| 68 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 29910 | -0.458 | -0.5852 | No |
| 69 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 29967 | -0.472 | -0.5837 | No |
| 70 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 30711 | -0.660 | -0.5996 | No |
| 71 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 30957 | -0.731 | -0.6015 | No |
| 72 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 31163 | -0.802 | -0.6019 | No |
| 73 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 31173 | -0.806 | -0.5970 | No |
| 74 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 31199 | -0.815 | -0.5924 | No |
| 75 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 31935 | -1.036 | -0.6057 | Yes |
| 76 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 32181 | -1.123 | -0.6051 | Yes |
| 77 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 32428 | -1.224 | -0.6039 | Yes |
| 78 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 32548 | -1.271 | -0.5990 | Yes |
| 79 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 32602 | -1.287 | -0.5922 | Yes |
| 80 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 32761 | -1.353 | -0.5878 | Yes |
| 81 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 32816 | -1.378 | -0.5804 | Yes |
| 82 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 32841 | -1.394 | -0.5721 | Yes |
| 83 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 32996 | -1.464 | -0.5669 | Yes |
| 84 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 33385 | -1.548 | -0.5675 | Yes |
| 85 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 33410 | -1.558 | -0.5582 | Yes |
| 86 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 33462 | -1.582 | -0.5494 | Yes |
| 87 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 33478 | -1.591 | -0.5396 | Yes |
| 88 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 33532 | -1.612 | -0.5307 | Yes |
| 89 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 33562 | -1.627 | -0.5211 | Yes |
| 90 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 33615 | -1.653 | -0.5119 | Yes |
| 91 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 33757 | -1.713 | -0.5047 | Yes |
| 92 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 33828 | -1.742 | -0.4955 | Yes |
| 93 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 33877 | -1.767 | -0.4854 | Yes |
| 94 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 33896 | -1.779 | -0.4745 | Yes |
| 95 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34042 | -1.851 | -0.4666 | Yes |
| 96 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 34124 | -1.889 | -0.4567 | Yes |
| 97 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 34144 | -1.898 | -0.4450 | Yes |
| 98 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 34171 | -1.915 | -0.4334 | Yes |
| 99 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 34323 | -2.005 | -0.4247 | Yes |
| 100 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 34330 | -2.008 | -0.4120 | Yes |
| 101 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 34447 | -2.060 | -0.4019 | Yes |
| 102 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 34474 | -2.074 | -0.3893 | Yes |
| 103 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 34543 | -2.116 | -0.3776 | Yes |
| 104 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 34554 | -2.124 | -0.3642 | Yes |
| 105 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 34783 | -2.267 | -0.3559 | Yes |
| 106 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 34945 | -2.381 | -0.3450 | Yes |
| 107 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 34954 | -2.383 | -0.3299 | Yes |
| 108 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 34962 | -2.383 | -0.3148 | Yes |
| 109 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 35211 | -2.525 | -0.3054 | Yes |
| 110 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 35294 | -2.582 | -0.2910 | Yes |
| 111 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 35321 | -2.603 | -0.2751 | Yes |
| 112 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 35393 | -2.670 | -0.2599 | Yes |
| 113 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 35415 | -2.670 | -0.2433 | Yes |
| 114 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 35505 | -2.750 | -0.2281 | Yes |
| 115 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 35526 | -2.770 | -0.2109 | Yes |
| 116 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 35907 | -3.081 | -0.2014 | Yes |
| 117 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35949 | -3.129 | -0.1825 | Yes |
| 118 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 36002 | -3.185 | -0.1635 | Yes |
| 119 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 36100 | -3.283 | -0.1451 | Yes |
| 120 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 36182 | -3.380 | -0.1256 | Yes |
| 121 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 36209 | -3.406 | -0.1045 | Yes |
| 122 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 36440 | -3.639 | -0.0874 | Yes |
| 123 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 36479 | -3.681 | -0.0648 | Yes |
| 124 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 36693 | -3.978 | -0.0451 | Yes |
| 125 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36881 | -4.323 | -0.0224 | Yes |
| 126 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36906 | -4.377 | 0.0050 | Yes |
