Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.49761787 |
| Normalized Enrichment Score (NES) | 1.3034793 |
| Nominal p-value | 0.023809524 |
| FDR q-value | 0.12886177 |
| FWER p-Value | 0.361 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 19 | 4.971 | 0.0415 | Yes |
| 2 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 36 | 4.945 | 0.0828 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 54 | 4.870 | 0.1235 | Yes |
| 4 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 60 | 4.855 | 0.1643 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.2024 | Yes |
| 6 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 148 | 4.393 | 0.2383 | Yes |
| 7 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 301 | 3.811 | 0.2663 | Yes |
| 8 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 351 | 3.623 | 0.2956 | Yes |
| 9 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 440 | 3.360 | 0.3216 | Yes |
| 10 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 495 | 3.227 | 0.3474 | Yes |
| 11 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 501 | 3.205 | 0.3743 | Yes |
| 12 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 514 | 3.169 | 0.4007 | Yes |
| 13 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 602 | 2.993 | 0.4237 | Yes |
| 14 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 657 | 2.884 | 0.4466 | Yes |
| 15 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 743 | 2.710 | 0.4671 | Yes |
| 16 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 793 | 2.613 | 0.4879 | Yes |
| 17 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 1474 | 1.802 | 0.4847 | Yes |
| 18 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 1615 | 1.743 | 0.4956 | Yes |
| 19 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 2247 | 1.270 | 0.4893 | Yes |
| 20 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 2323 | 1.226 | 0.4976 | Yes |
| 21 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 3013 | 0.890 | 0.4865 | No |
| 22 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 3140 | 0.851 | 0.4903 | No |
| 23 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 3618 | 0.663 | 0.4830 | No |
| 24 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 4151 | 0.486 | 0.4727 | No |
| 25 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 4474 | 0.372 | 0.4671 | No |
| 26 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 4626 | 0.333 | 0.4658 | No |
| 27 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 4908 | 0.259 | 0.4604 | No |
| 28 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 5106 | 0.199 | 0.4568 | No |
| 29 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 5139 | 0.191 | 0.4575 | No |
| 30 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 5232 | 0.162 | 0.4564 | No |
| 31 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 5237 | 0.160 | 0.4576 | No |
| 32 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 5569 | 0.153 | 0.4500 | No |
| 33 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6220 | 0.000 | 0.4324 | No |
| 34 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6238 | 0.000 | 0.4319 | No |
| 35 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 6751 | 0.000 | 0.4181 | No |
| 36 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7281 | 0.000 | 0.4037 | No |
| 37 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 7727 | 0.000 | 0.3917 | No |
| 38 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 7952 | 0.000 | 0.3856 | No |
| 39 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8205 | 0.000 | 0.3788 | No |
| 40 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8255 | 0.000 | 0.3775 | No |
| 41 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9364 | 0.000 | 0.3475 | No |
| 42 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9447 | 0.000 | 0.3453 | No |
| 43 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9670 | 0.000 | 0.3393 | No |
| 44 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9745 | 0.000 | 0.3373 | No |
| 45 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 9846 | 0.000 | 0.3346 | No |
| 46 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 9849 | 0.000 | 0.3345 | No |
| 47 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9852 | 0.000 | 0.3345 | No |
| 48 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10265 | 0.000 | 0.3233 | No |
| 49 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11321 | 0.000 | 0.2948 | No |
| 50 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11431 | 0.000 | 0.2918 | No |
| 51 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11439 | 0.000 | 0.2916 | No |
| 52 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11460 | 0.000 | 0.2911 | No |
| 53 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 11787 | 0.000 | 0.2823 | No |
| 54 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 11812 | 0.000 | 0.2816 | No |
| 55 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 11837 | 0.000 | 0.2810 | No |
| 56 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 12069 | 0.000 | 0.2747 | No |
| 57 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12242 | 0.000 | 0.2701 | No |
| 58 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12511 | 0.000 | 0.2628 | No |
| 59 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 12572 | 0.000 | 0.2612 | No |
| 60 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12632 | 0.000 | 0.2596 | No |
| 61 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 13123 | 0.000 | 0.2463 | No |
| 62 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13325 | 0.000 | 0.2409 | No |
| 63 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13333 | 0.000 | 0.2407 | No |
| 64 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13668 | 0.000 | 0.2317 | No |
| 65 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 13750 | 0.000 | 0.2295 | No |
| 66 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14085 | 0.000 | 0.2204 | No |
| 67 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14416 | 0.000 | 0.2115 | No |
| 68 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 15926 | 0.000 | 0.1707 | No |
| 69 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16091 | 0.000 | 0.1662 | No |
| 70 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16183 | 0.000 | 0.1638 | No |
| 71 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17435 | 0.000 | 0.1299 | No |
| 72 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17508 | 0.000 | 0.1280 | No |
| 73 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17782 | 0.000 | 0.1206 | No |
| 74 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17793 | 0.000 | 0.1203 | No |
| 75 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18161 | 0.000 | 0.1104 | No |
| 76 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18167 | 0.000 | 0.1103 | No |
| 77 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18917 | 0.000 | 0.0900 | No |
| 78 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18936 | 0.000 | 0.0895 | No |
| 79 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19061 | 0.000 | 0.0862 | No |
| 80 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19084 | 0.000 | 0.0856 | No |
| 81 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19150 | 0.000 | 0.0838 | No |
| 82 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19295 | 0.000 | 0.0799 | No |
| 83 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19806 | 0.000 | 0.0661 | No |
| 84 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 19848 | 0.000 | 0.0650 | No |
| 85 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 19985 | 0.000 | 0.0613 | No |
| 86 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 20342 | 0.000 | 0.0517 | No |
| 87 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 20697 | 0.000 | 0.0421 | No |
| 88 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20701 | 0.000 | 0.0420 | No |
| 89 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 20702 | 0.000 | 0.0420 | No |
| 90 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 20868 | 0.000 | 0.0376 | No |
| 91 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 20886 | 0.000 | 0.0371 | No |
| 92 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 21278 | 0.000 | 0.0265 | No |
| 93 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 21787 | 0.000 | 0.0128 | No |
| 94 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21853 | 0.000 | 0.0110 | No |
| 95 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 22334 | 0.000 | -0.0020 | No |
| 96 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 22908 | 0.000 | -0.0175 | No |
| 97 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 23106 | 0.000 | -0.0228 | No |
| 98 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 23730 | 0.000 | -0.0397 | No |
| 99 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 23737 | 0.000 | -0.0398 | No |
| 100 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 24158 | 0.000 | -0.0512 | No |
| 101 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 24171 | 0.000 | -0.0515 | No |
| 102 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24352 | 0.000 | -0.0564 | No |
| 103 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 24374 | 0.000 | -0.0570 | No |
| 104 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 24776 | 0.000 | -0.0678 | No |
| 105 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 25169 | 0.000 | -0.0784 | No |
| 106 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 25362 | 0.000 | -0.0836 | No |
| 107 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 25936 | 0.000 | -0.0991 | No |
| 108 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 26704 | 0.000 | -0.1199 | No |
| 109 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 26705 | 0.000 | -0.1199 | No |
| 110 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 26848 | 0.000 | -0.1237 | No |
| 111 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 27799 | 0.000 | -0.1494 | No |
| 112 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 28169 | -0.000 | -0.1594 | No |
| 113 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 28961 | -0.226 | -0.1789 | No |
| 114 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 28972 | -0.231 | -0.1772 | No |
| 115 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 29275 | -0.304 | -0.1828 | No |
| 116 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 29464 | -0.352 | -0.1849 | No |
| 117 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 29828 | -0.436 | -0.1911 | No |
| 118 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 31406 | -0.860 | -0.2265 | No |
| 119 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 31448 | -0.874 | -0.2202 | No |
| 120 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 32582 | -1.286 | -0.2400 | No |
| 121 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 33078 | -1.499 | -0.2407 | No |
| 122 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 33846 | -1.754 | -0.2467 | No |
| 123 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 34592 | -2.145 | -0.2487 | No |
| 124 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 34711 | -2.225 | -0.2331 | No |
| 125 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 35151 | -2.472 | -0.2241 | No |
| 126 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 35264 | -2.560 | -0.2056 | No |
| 127 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 35698 | -2.901 | -0.1928 | No |
| 128 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 35719 | -2.918 | -0.1687 | No |
| 129 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 35779 | -2.974 | -0.1452 | No |
| 130 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 35864 | -3.040 | -0.1218 | No |
| 131 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 36368 | -3.558 | -0.1053 | No |
| 132 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 36391 | -3.584 | -0.0757 | No |
| 133 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36432 | -3.628 | -0.0461 | No |
| 134 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 36442 | -3.641 | -0.0156 | No |
| 135 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 36644 | -3.920 | 0.0121 | No |
