Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5771683 |
| Normalized Enrichment Score (NES) | 1.4825819 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.093245 |
| FWER p-Value | 0.105 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 38 | 4.937 | 0.0320 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 39 | 4.920 | 0.0649 | Yes |
| 3 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 106 | 4.607 | 0.0940 | Yes |
| 4 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 111 | 4.590 | 0.1246 | Yes |
| 5 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 118 | 4.550 | 0.1549 | Yes |
| 6 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 122 | 4.520 | 0.1851 | Yes |
| 7 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 124 | 4.510 | 0.2152 | Yes |
| 8 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 258 | 3.964 | 0.2382 | Yes |
| 9 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 314 | 3.749 | 0.2618 | Yes |
| 10 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 334 | 3.650 | 0.2857 | Yes |
| 11 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 528 | 3.114 | 0.3013 | Yes |
| 12 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 571 | 3.068 | 0.3207 | Yes |
| 13 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 788 | 2.615 | 0.3323 | Yes |
| 14 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 882 | 2.543 | 0.3469 | Yes |
| 15 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 973 | 2.393 | 0.3604 | Yes |
| 16 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 1071 | 2.234 | 0.3728 | Yes |
| 17 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 1100 | 2.196 | 0.3867 | Yes |
| 18 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 1151 | 2.127 | 0.3996 | Yes |
| 19 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 1217 | 2.039 | 0.4115 | Yes |
| 20 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 1411 | 1.824 | 0.4185 | Yes |
| 21 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 1444 | 1.802 | 0.4296 | Yes |
| 22 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 1558 | 1.801 | 0.4386 | Yes |
| 23 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1594 | 1.765 | 0.4495 | Yes |
| 24 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 1625 | 1.732 | 0.4603 | Yes |
| 25 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1636 | 1.719 | 0.4715 | Yes |
| 26 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 1716 | 1.632 | 0.4803 | Yes |
| 27 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1788 | 1.579 | 0.4890 | Yes |
| 28 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1848 | 1.539 | 0.4977 | Yes |
| 29 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 2088 | 1.371 | 0.5004 | Yes |
| 30 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2150 | 1.327 | 0.5076 | Yes |
| 31 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 2306 | 1.236 | 0.5117 | Yes |
| 32 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 2348 | 1.203 | 0.5186 | Yes |
| 33 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 2645 | 1.062 | 0.5177 | Yes |
| 34 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 2654 | 1.058 | 0.5246 | Yes |
| 35 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 2723 | 1.020 | 0.5296 | Yes |
| 36 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 2756 | 1.007 | 0.5355 | Yes |
| 37 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 2821 | 0.982 | 0.5403 | Yes |
| 38 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 2860 | 0.963 | 0.5457 | Yes |
| 39 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2961 | 0.915 | 0.5491 | Yes |
| 40 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 2966 | 0.911 | 0.5551 | Yes |
| 41 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 3121 | 0.861 | 0.5567 | Yes |
| 42 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 3132 | 0.854 | 0.5622 | Yes |
| 43 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 3268 | 0.795 | 0.5638 | Yes |
| 44 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 3312 | 0.776 | 0.5678 | Yes |
| 45 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 3329 | 0.771 | 0.5726 | Yes |
| 46 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 3348 | 0.759 | 0.5772 | Yes |
| 47 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 3669 | 0.645 | 0.5728 | No |
| 48 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 3810 | 0.601 | 0.5731 | No |
| 49 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 4277 | 0.439 | 0.5634 | No |
| 50 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4327 | 0.418 | 0.5649 | No |
| 51 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 4816 | 0.281 | 0.5535 | No |
| 52 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 4986 | 0.234 | 0.5505 | No |
| 53 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 5261 | 0.154 | 0.5442 | No |
| 54 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 5741 | 0.123 | 0.5320 | No |
| 55 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 5822 | 0.098 | 0.5305 | No |
| 56 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 5925 | 0.064 | 0.5282 | No |
| 57 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 6082 | 0.019 | 0.5241 | No |
| 58 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6323 | 0.000 | 0.5176 | No |
| 59 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9246 | 0.000 | 0.4386 | No |
| 60 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9609 | 0.000 | 0.4288 | No |
| 61 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9813 | 0.000 | 0.4233 | No |
| 62 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 9888 | 0.000 | 0.4213 | No |
| 63 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10884 | 0.000 | 0.3944 | No |
| 64 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11010 | 0.000 | 0.3910 | No |
| 65 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11053 | 0.000 | 0.3898 | No |
| 66 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11643 | 0.000 | 0.3739 | No |
| 67 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11723 | 0.000 | 0.3718 | No |
| 68 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12054 | 0.000 | 0.3629 | No |
| 69 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12349 | 0.000 | 0.3549 | No |
| 70 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 12901 | 0.000 | 0.3400 | No |
| 71 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13726 | 0.000 | 0.3177 | No |
| 72 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14053 | 0.000 | 0.3089 | No |
| 73 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16271 | 0.000 | 0.2489 | No |
| 74 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17062 | 0.000 | 0.2275 | No |
| 75 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 17957 | 0.000 | 0.2034 | No |
| 76 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19286 | 0.000 | 0.1674 | No |
| 77 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 20738 | 0.000 | 0.1282 | No |
| 78 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 20770 | 0.000 | 0.1274 | No |
| 79 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 21573 | 0.000 | 0.1057 | No |
| 80 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 21783 | 0.000 | 0.1000 | No |
| 81 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 22203 | 0.000 | 0.0887 | No |
| 82 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 23016 | 0.000 | 0.0667 | No |
| 83 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 23823 | 0.000 | 0.0449 | No |
| 84 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 24233 | 0.000 | 0.0338 | No |
| 85 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 24321 | 0.000 | 0.0315 | No |
| 86 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 25730 | 0.000 | -0.0066 | No |
| 87 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 25986 | 0.000 | -0.0135 | No |
| 88 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 26737 | 0.000 | -0.0338 | No |
| 89 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 27686 | 0.000 | -0.0594 | No |
| 90 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 28207 | -0.011 | -0.0734 | No |
| 91 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 28404 | -0.068 | -0.0783 | No |
| 92 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28750 | -0.168 | -0.0865 | No |
| 93 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 28846 | -0.196 | -0.0877 | No |
| 94 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 28902 | -0.210 | -0.0878 | No |
| 95 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 29027 | -0.238 | -0.0896 | No |
| 96 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 29295 | -0.310 | -0.0947 | No |
| 97 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 29339 | -0.319 | -0.0938 | No |
| 98 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 29407 | -0.337 | -0.0933 | No |
| 99 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 29409 | -0.337 | -0.0911 | No |
| 100 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 29458 | -0.350 | -0.0901 | No |
| 101 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 30097 | -0.510 | -0.1039 | No |
| 102 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 30848 | -0.693 | -0.1196 | No |
| 103 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 31194 | -0.813 | -0.1234 | No |
| 104 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 31294 | -0.850 | -0.1204 | No |
| 105 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 31745 | -0.975 | -0.1261 | No |
| 106 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 31853 | -1.008 | -0.1222 | No |
| 107 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 31861 | -1.010 | -0.1157 | No |
| 108 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 31979 | -1.057 | -0.1117 | No |
| 109 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 32512 | -1.255 | -0.1177 | No |
| 110 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 32534 | -1.265 | -0.1098 | No |
| 111 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 32549 | -1.271 | -0.1017 | No |
| 112 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 33139 | -1.524 | -0.1074 | No |
| 113 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 33786 | -1.725 | -0.1134 | No |
| 114 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 33912 | -1.787 | -0.1048 | No |
| 115 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 35003 | -2.383 | -0.1183 | No |
| 116 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35345 | -2.621 | -0.1100 | No |
| 117 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 35443 | -2.694 | -0.0946 | No |
| 118 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 35516 | -2.758 | -0.0781 | No |
| 119 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35837 | -3.017 | -0.0665 | No |
| 120 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 36386 | -3.579 | -0.0574 | No |
| 121 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 36499 | -3.693 | -0.0357 | No |
| 122 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36596 | -3.855 | -0.0125 | No |
| 123 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36606 | -3.864 | 0.0131 | No |
