Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.68974847 |
| Normalized Enrichment Score (NES) | -1.4773517 |
| Nominal p-value | 0.0022624435 |
| FDR q-value | 0.06392419 |
| FWER p-Value | 0.142 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 61 | 4.853 | 0.0212 | No |
| 2 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 211 | 4.133 | 0.0366 | No |
| 3 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 249 | 4.004 | 0.0544 | No |
| 4 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 326 | 3.698 | 0.0698 | No |
| 5 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 591 | 3.020 | 0.0768 | No |
| 6 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 655 | 2.887 | 0.0887 | No |
| 7 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 692 | 2.812 | 0.1010 | No |
| 8 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 2010 | 1.414 | 0.0720 | No |
| 9 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 2455 | 1.146 | 0.0654 | No |
| 10 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 3671 | 0.644 | 0.0355 | No |
| 11 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 5251 | 0.156 | -0.0065 | No |
| 12 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 5554 | 0.153 | -0.0139 | No |
| 13 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6541 | 0.000 | -0.0406 | No |
| 14 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7977 | 0.000 | -0.0794 | No |
| 15 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9312 | 0.000 | -0.1155 | No |
| 16 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9531 | 0.000 | -0.1214 | No |
| 17 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9575 | 0.000 | -0.1226 | No |
| 18 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10456 | 0.000 | -0.1464 | No |
| 19 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11207 | 0.000 | -0.1667 | No |
| 20 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12005 | 0.000 | -0.1882 | No |
| 21 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12308 | 0.000 | -0.1964 | No |
| 22 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12458 | 0.000 | -0.2004 | No |
| 23 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12469 | 0.000 | -0.2007 | No |
| 24 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12501 | 0.000 | -0.2015 | No |
| 25 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12771 | 0.000 | -0.2088 | No |
| 26 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12772 | 0.000 | -0.2088 | No |
| 27 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13374 | 0.000 | -0.2251 | No |
| 28 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 13701 | 0.000 | -0.2339 | No |
| 29 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14691 | 0.000 | -0.2607 | No |
| 30 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 15442 | 0.000 | -0.2810 | No |
| 31 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15932 | 0.000 | -0.2942 | No |
| 32 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16170 | 0.000 | -0.3006 | No |
| 33 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16243 | 0.000 | -0.3025 | No |
| 34 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16393 | 0.000 | -0.3066 | No |
| 35 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16495 | 0.000 | -0.3093 | No |
| 36 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17473 | 0.000 | -0.3357 | No |
| 37 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18715 | 0.000 | -0.3693 | No |
| 38 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18716 | 0.000 | -0.3693 | No |
| 39 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18993 | 0.000 | -0.3768 | No |
| 40 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19682 | 0.000 | -0.3954 | No |
| 41 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19828 | 0.000 | -0.3993 | No |
| 42 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 21373 | 0.000 | -0.4411 | No |
| 43 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 21684 | 0.000 | -0.4495 | No |
| 44 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 22875 | 0.000 | -0.4817 | No |
| 45 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 25046 | 0.000 | -0.5404 | No |
| 46 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 25936 | 0.000 | -0.5644 | No |
| 47 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 26176 | 0.000 | -0.5709 | No |
| 48 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26725 | 0.000 | -0.5857 | No |
| 49 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 27333 | 0.000 | -0.6022 | No |
| 50 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 28189 | -0.005 | -0.6253 | No |
| 51 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 28689 | -0.150 | -0.6381 | No |
| 52 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 29035 | -0.241 | -0.6463 | No |
| 53 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 29362 | -0.324 | -0.6536 | No |
| 54 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 29696 | -0.404 | -0.6607 | No |
| 55 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 29993 | -0.479 | -0.6664 | No |
| 56 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30103 | -0.511 | -0.6670 | No |
| 57 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 30480 | -0.601 | -0.6743 | No |
| 58 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 30738 | -0.669 | -0.6781 | No |
| 59 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 30984 | -0.736 | -0.6813 | No |
| 60 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 31192 | -0.813 | -0.6831 | No |
| 61 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.6856 | Yes |
| 62 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31473 | -0.884 | -0.6824 | Yes |
| 63 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 31529 | -0.905 | -0.6796 | Yes |
| 64 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 31539 | -0.907 | -0.6756 | Yes |
| 65 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 31595 | -0.924 | -0.6727 | Yes |
| 66 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.6719 | Yes |
| 67 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 31868 | -1.012 | -0.6707 | Yes |
| 68 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31890 | -1.021 | -0.6665 | Yes |
| 69 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31894 | -1.023 | -0.6617 | Yes |
| 70 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 32023 | -1.073 | -0.6601 | Yes |
| 71 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 32491 | -1.246 | -0.6669 | Yes |
| 72 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 32621 | -1.296 | -0.6643 | Yes |
| 73 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 32644 | -1.306 | -0.6588 | Yes |
| 74 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.6538 | Yes |
| 75 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 33014 | -1.473 | -0.6556 | Yes |
| 76 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 33050 | -1.488 | -0.6495 | Yes |
| 77 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 33358 | -1.533 | -0.6506 | Yes |
| 78 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 33494 | -1.600 | -0.6467 | Yes |
| 79 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 33610 | -1.650 | -0.6421 | Yes |
| 80 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33683 | -1.683 | -0.6361 | Yes |
| 81 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 33751 | -1.710 | -0.6299 | Yes |
| 82 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 33944 | -1.801 | -0.6266 | Yes |
| 83 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 33965 | -1.809 | -0.6186 | Yes |
| 84 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 34317 | -2.002 | -0.6187 | Yes |
| 85 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.6122 | Yes |
| 86 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 34684 | -2.201 | -0.6086 | Yes |
| 87 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 34800 | -2.282 | -0.6009 | Yes |
| 88 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.5906 | Yes |
| 89 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34829 | -2.298 | -0.5801 | Yes |
| 90 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 34863 | -2.322 | -0.5701 | Yes |
| 91 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34936 | -2.377 | -0.5608 | Yes |
| 92 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35168 | -2.486 | -0.5554 | Yes |
| 93 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35187 | -2.501 | -0.5441 | Yes |
| 94 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 35372 | -2.651 | -0.5366 | Yes |
| 95 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35448 | -2.698 | -0.5260 | Yes |
| 96 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 35457 | -2.706 | -0.5134 | Yes |
| 97 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 35509 | -2.752 | -0.5019 | Yes |
| 98 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.4899 | Yes |
| 99 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35559 | -2.806 | -0.4768 | Yes |
| 100 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35595 | -2.845 | -0.4644 | Yes |
| 101 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.4515 | Yes |
| 102 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.4381 | Yes |
| 103 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 35642 | -2.897 | -0.4249 | Yes |
| 104 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 35783 | -2.979 | -0.4147 | Yes |
| 105 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35848 | -3.029 | -0.4022 | Yes |
| 106 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 35922 | -3.092 | -0.3896 | Yes |
| 107 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.3753 | Yes |
| 108 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35937 | -3.113 | -0.3607 | Yes |
| 109 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36045 | -3.244 | -0.3483 | Yes |
| 110 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36087 | -3.264 | -0.3341 | Yes |
| 111 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36199 | -3.393 | -0.3211 | Yes |
| 112 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36221 | -3.418 | -0.3056 | Yes |
| 113 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36253 | -3.459 | -0.2902 | Yes |
| 114 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 36267 | -3.475 | -0.2742 | Yes |
| 115 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.2578 | Yes |
| 116 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.2432 | Yes |
| 117 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36357 | -3.546 | -0.2268 | Yes |
| 118 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36377 | -3.570 | -0.2106 | Yes |
| 119 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36385 | -3.578 | -0.1939 | Yes |
| 120 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 36409 | -3.596 | -0.1776 | Yes |
| 121 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.1651 | Yes |
| 122 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36631 | -3.907 | -0.1468 | Yes |
| 123 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 36704 | -3.990 | -0.1300 | Yes |
| 124 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36717 | -4.001 | -0.1115 | Yes |
| 125 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36767 | -4.074 | -0.0937 | Yes |
| 126 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36783 | -4.105 | -0.0748 | Yes |
| 127 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36804 | -4.128 | -0.0559 | Yes |
| 128 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36807 | -4.129 | -0.0365 | Yes |
| 129 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36922 | -4.425 | -0.0188 | Yes |
| 130 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 37073 | -4.955 | 0.0005 | Yes |
