Fig 1: Enrichment plot: DESCARTES_FETAL_HEART_STROMAL_CELLS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | DESCARTES_FETAL_HEART_STROMAL_CELLS |
| Enrichment Score (ES) | -0.8981839 |
| Normalized Enrichment Score (NES) | -1.6568422 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.5862223E-4 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6185 | 0.000 | -0.1669 | No |
| 2 | ANGPTL1 | angiopoietin like 1 [Source:HGNC Symbol;Acc:HGNC:489] | 6802 | 0.000 | -0.1835 | No |
| 3 | NPTX2 | neuronal pentraxin 2 [Source:HGNC Symbol;Acc:HGNC:7953] | 7207 | 0.000 | -0.1944 | No |
| 4 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7366 | 0.000 | -0.1987 | No |
| 5 | AGTR2 | angiotensin II receptor type 2 [Source:HGNC Symbol;Acc:HGNC:338] | 9523 | 0.000 | -0.2569 | No |
| 6 | RTL3 | retrotransposon Gag like 3 [Source:HGNC Symbol;Acc:HGNC:22997] | 10377 | 0.000 | -0.2799 | No |
| 7 | CILP | cartilage intermediate layer protein [Source:HGNC Symbol;Acc:HGNC:1980] | 10776 | 0.000 | -0.2906 | No |
| 8 | FBLN1 | fibulin 1 [Source:HGNC Symbol;Acc:HGNC:3600] | 11206 | 0.000 | -0.3022 | No |
| 9 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12771 | 0.000 | -0.3444 | No |
| 10 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12772 | 0.000 | -0.3444 | No |
| 11 | LPAR4 | lysophosphatidic acid receptor 4 [Source:HGNC Symbol;Acc:HGNC:4478] | 13641 | 0.000 | -0.3678 | No |
| 12 | HTRA3 | HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406] | 15593 | 0.000 | -0.4205 | No |
| 13 | DCN | decorin [Source:HGNC Symbol;Acc:HGNC:2705] | 15928 | 0.000 | -0.4295 | No |
| 14 | DPT | dermatopontin [Source:HGNC Symbol;Acc:HGNC:3011] | 16112 | 0.000 | -0.4344 | No |
| 15 | ABCA10 | ATP binding cassette subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:30] | 16274 | 0.000 | -0.4388 | No |
| 16 | LUM | lumican [Source:HGNC Symbol;Acc:HGNC:6724] | 18760 | 0.000 | -0.5058 | No |
| 17 | NRK | Nik related kinase [Source:HGNC Symbol;Acc:HGNC:25391] | 19396 | 0.000 | -0.5230 | No |
| 18 | PRELP | proline and arginine rich end leucine rich repeat protein [Source:HGNC Symbol;Acc:HGNC:9357] | 21025 | 0.000 | -0.5669 | No |
| 19 | EMILIN3 | elastin microfibril interfacer 3 [Source:HGNC Symbol;Acc:HGNC:16123] | 21660 | 0.000 | -0.5840 | No |
| 20 | SCARA5 | scavenger receptor class A member 5 [Source:HGNC Symbol;Acc:HGNC:28701] | 22185 | 0.000 | -0.5982 | No |
| 21 | MFAP5 | microfibril associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29673] | 22665 | 0.000 | -0.6111 | No |
| 22 | ABCA9 | ATP binding cassette subfamily A member 9 [Source:HGNC Symbol;Acc:HGNC:39] | 24069 | 0.000 | -0.6489 | No |
| 23 | ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2 [Source:HGNC Symbol;Acc:HGNC:218] | 24694 | 0.000 | -0.6658 | No |
| 24 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 24799 | 0.000 | -0.6686 | No |
| 25 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 25169 | 0.000 | -0.6785 | No |
| 26 | ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif 19 [Source:HGNC Symbol;Acc:HGNC:17111] | 25572 | 0.000 | -0.6894 | No |
| 27 | ISLR | immunoglobulin superfamily containing leucine rich repeat [Source:HGNC Symbol;Acc:HGNC:6133] | 26960 | 0.000 | -0.7268 | No |
| 28 | CCN3 | cellular communication network factor 3 [Source:HGNC Symbol;Acc:HGNC:7885] | 27872 | 0.000 | -0.7514 | No |
| 29 | GPC3 | glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451] | 27985 | 0.000 | -0.7544 | No |
| 30 | TARID | TCF21 antisense RNA inducing promoter demethylation [Source:HGNC Symbol;Acc:HGNC:50506] | 28053 | 0.000 | -0.7562 | No |
| 31 | C1QTNF12 | C1q and TNF related 12 [Source:HGNC Symbol;Acc:HGNC:32308] | 33314 | -1.529 | -0.7628 | Yes |
| 32 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 33358 | -1.533 | -0.6283 | Yes |
| 33 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36783 | -4.105 | -0.3572 | Yes |
| 34 | ANGPTL6 | angiopoietin like 6 [Source:HGNC Symbol;Acc:HGNC:23140] | 36805 | -4.129 | 0.0077 | Yes |
