Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | TRAVAGLINI_LUNG_MUCOUS_CELL |
| Enrichment Score (ES) | 0.6566932 |
| Normalized Enrichment Score (NES) | 1.6771669 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.049199246 |
| FWER p-Value | 0.152 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 10 | 4.988 | 0.0367 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 15 | 4.981 | 0.0734 | Yes |
| 3 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 33 | 4.951 | 0.1096 | Yes |
| 4 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 40 | 4.914 | 0.1459 | Yes |
| 5 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 42 | 4.905 | 0.1822 | Yes |
| 6 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 69 | 4.814 | 0.2171 | Yes |
| 7 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.2506 | Yes |
| 8 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 164 | 4.313 | 0.2809 | Yes |
| 9 | TGM2 | transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778] | 167 | 4.292 | 0.3126 | Yes |
| 10 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 183 | 4.220 | 0.3435 | Yes |
| 11 | CPD | carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301] | 206 | 4.166 | 0.3737 | Yes |
| 12 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 351 | 3.623 | 0.3966 | Yes |
| 13 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 460 | 3.318 | 0.4183 | Yes |
| 14 | C15orf48 | chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898] | 526 | 3.116 | 0.4396 | Yes |
| 15 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 541 | 3.096 | 0.4622 | Yes |
| 16 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 606 | 2.983 | 0.4825 | Yes |
| 17 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862] | 637 | 2.920 | 0.5033 | Yes |
| 18 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 742 | 2.715 | 0.5206 | Yes |
| 19 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 763 | 2.669 | 0.5399 | Yes |
| 20 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 867 | 2.565 | 0.5561 | Yes |
| 21 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 925 | 2.476 | 0.5729 | Yes |
| 22 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 926 | 2.470 | 0.5911 | Yes |
| 23 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 1170 | 2.118 | 0.6003 | Yes |
| 24 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1405 | 1.834 | 0.6075 | Yes |
| 25 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 1411 | 1.824 | 0.6209 | Yes |
| 26 | BID | BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050] | 1495 | 1.802 | 0.6320 | Yes |
| 27 | TNIP3 | TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] | 1696 | 1.646 | 0.6388 | Yes |
| 28 | REEP3 | receptor accessory protein 3 [Source:HGNC Symbol;Acc:HGNC:23711] | 1819 | 1.557 | 0.6470 | Yes |
| 29 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1877 | 1.518 | 0.6567 | Yes |
| 30 | MED24 | mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963] | 2249 | 1.269 | 0.6561 | No |
| 31 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 2851 | 0.966 | 0.6470 | No |
| 32 | RDH10 | retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975] | 3828 | 0.592 | 0.6249 | No |
| 33 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 5265 | 0.154 | 0.5872 | No |
| 34 | XBP1 | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | 5902 | 0.073 | 0.5706 | No |
| 35 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6220 | 0.000 | 0.5620 | No |
| 36 | MUCL1 | mucin like 1 [Source:HGNC Symbol;Acc:HGNC:30588] | 6315 | 0.000 | 0.5594 | No |
| 37 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7021 | 0.000 | 0.5404 | No |
| 38 | WFDC2 | WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939] | 8019 | 0.000 | 0.5134 | No |
| 39 | PROM1 | prominin 1 [Source:HGNC Symbol;Acc:HGNC:9454] | 8137 | 0.000 | 0.5102 | No |
| 40 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8424 | 0.000 | 0.5025 | No |
| 41 | CRISP3 | cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904] | 9006 | 0.000 | 0.4868 | No |
| 42 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9109 | 0.000 | 0.4840 | No |
| 43 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9197 | 0.000 | 0.4817 | No |
| 44 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9346 | 0.000 | 0.4777 | No |
| 45 | ADAM28 | ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206] | 9589 | 0.000 | 0.4711 | No |
| 46 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 9888 | 0.000 | 0.4631 | No |
| 47 | CYP2F1 | cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632] | 10258 | 0.000 | 0.4531 | No |
| 48 | KLK10 | kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358] | 10363 | 0.000 | 0.4503 | No |
| 49 | KLK11 | kallikrein related peptidase 11 [Source:HGNC Symbol;Acc:HGNC:6359] | 10364 | 0.000 | 0.4503 | No |
| 50 | KLK12 | kallikrein related peptidase 12 [Source:HGNC Symbol;Acc:HGNC:6360] | 10365 | 0.000 | 0.4503 | No |
| 51 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10643 | 0.000 | 0.4428 | No |
| 52 | LCN2 | lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526] | 10841 | 0.000 | 0.4374 | No |
| 53 | SLC26A4 | solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] | 11090 | 0.000 | 0.4307 | No |
| 54 | TSPAN8 | tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855] | 11450 | 0.000 | 0.4210 | No |
| 55 | AKR1C1 | aldo-keto reductase family 1 member C1 [Source:HGNC Symbol;Acc:HGNC:384] | 11491 | 0.000 | 0.4199 | No |
| 56 | AKR1C2 | aldo-keto reductase family 1 member C2 [Source:HGNC Symbol;Acc:HGNC:385] | 11493 | 0.000 | 0.4199 | No |
| 57 | S100P | S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] | 11604 | 0.000 | 0.4169 | No |
| 58 | BACE2 | beta-secretase 2 [Source:HGNC Symbol;Acc:HGNC:934] | 11672 | 0.000 | 0.4151 | No |
| 59 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11723 | 0.000 | 0.4138 | No |
| 60 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] | 12074 | 0.000 | 0.4043 | No |
| 61 | MSMB | microseminoprotein beta [Source:HGNC Symbol;Acc:HGNC:7372] | 12281 | 0.000 | 0.3987 | No |
| 62 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12319 | 0.000 | 0.3977 | No |
| 63 | VMO1 | vitelline membrane outer layer 1 homolog [Source:HGNC Symbol;Acc:HGNC:30387] | 12365 | 0.000 | 0.3965 | No |
| 64 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12679 | 0.000 | 0.3880 | No |
| 65 | MUC4 | mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514] | 12705 | 0.000 | 0.3874 | No |
| 66 | LINC00342 | long intergenic non-protein coding RNA 342 [Source:HGNC Symbol;Acc:HGNC:42470] | 12902 | 0.000 | 0.3821 | No |
| 67 | ZG16B | zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456] | 13176 | 0.000 | 0.3747 | No |
| 68 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 14282 | 0.000 | 0.3448 | No |
| 69 | TMC5 | transmembrane channel like 5 [Source:HGNC Symbol;Acc:HGNC:22999] | 14346 | 0.000 | 0.3431 | No |
| 70 | TMEM45A | transmembrane protein 45A [Source:HGNC Symbol;Acc:HGNC:25480] | 14702 | 0.000 | 0.3335 | No |
| 71 | CDC42EP5 | CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] | 16063 | 0.000 | 0.2967 | No |
| 72 | BPIFA1 | BPI fold containing family A member 1 [Source:HGNC Symbol;Acc:HGNC:15749] | 17542 | 0.000 | 0.2567 | No |
| 73 | BPIFB1 | BPI fold containing family B member 1 [Source:HGNC Symbol;Acc:HGNC:16108] | 17592 | 0.000 | 0.2554 | No |
| 74 | ANKRD36C | ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946] | 17802 | 0.000 | 0.2497 | No |
| 75 | HILPDA | hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859] | 17855 | 0.000 | 0.2483 | No |
| 76 | KDR | kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] | 18240 | 0.000 | 0.2379 | No |
| 77 | HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943] | 18376 | 0.000 | 0.2343 | No |
| 78 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18377 | 0.000 | 0.2343 | No |
| 79 | LTF | lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720] | 18728 | 0.000 | 0.2248 | No |
| 80 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 19110 | 0.000 | 0.2145 | No |
| 81 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19463 | 0.000 | 0.2050 | No |
| 82 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19468 | 0.000 | 0.2049 | No |
| 83 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19477 | 0.000 | 0.2047 | No |
| 84 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19479 | 0.000 | 0.2046 | No |
| 85 | SMIM31 | small integral membrane protein 31 [Source:HGNC Symbol;Acc:HGNC:49638] | 19738 | 0.000 | 0.1977 | No |
| 86 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19806 | 0.000 | 0.1958 | No |
| 87 | SCGB3A1 | secretoglobin family 3A member 1 [Source:HGNC Symbol;Acc:HGNC:18384] | 20551 | 0.000 | 0.1757 | No |
| 88 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 21268 | 0.000 | 0.1563 | No |
| 89 | RARRES1 | retinoic acid receptor responder 1 [Source:HGNC Symbol;Acc:HGNC:9867] | 21409 | 0.000 | 0.1526 | No |
| 90 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 21482 | 0.000 | 0.1506 | No |
| 91 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 21490 | 0.000 | 0.1504 | No |
| 92 | CSTB | cystatin B [Source:HGNC Symbol;Acc:HGNC:2482] | 21781 | 0.000 | 0.1426 | No |
| 93 | TFPI2 | tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] | 22048 | 0.000 | 0.1354 | No |
| 94 | SLC4A4 | solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030] | 22500 | 0.000 | 0.1232 | No |
| 95 | RIMS1 | regulating synaptic membrane exocytosis 1 [Source:HGNC Symbol;Acc:HGNC:17282] | 22578 | 0.000 | 0.1211 | No |
| 96 | ALDH1A3 | aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409] | 22858 | 0.000 | 0.1135 | No |
| 97 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 22908 | 0.000 | 0.1122 | No |
| 98 | AZGP1 | alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:910] | 23916 | 0.000 | 0.0850 | No |
| 99 | FCGBP | Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572] | 23986 | 0.000 | 0.0831 | No |
| 100 | PI3 | peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] | 24678 | 0.000 | 0.0644 | No |
| 101 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 24862 | 0.000 | 0.0595 | No |
| 102 | TFF3 | trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757] | 25393 | 0.000 | 0.0451 | No |
| 103 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 26905 | 0.000 | 0.0043 | No |
| 104 | PIGR | polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968] | 27684 | 0.000 | -0.0168 | No |
| 105 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | -0.0210 | No |
| 106 | TMEM165 | transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760] | 28292 | -0.032 | -0.0329 | No |
| 107 | HIPK2 | homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402] | 28793 | -0.179 | -0.0451 | No |
| 108 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 28972 | -0.231 | -0.0483 | No |
| 109 | ANPEP | alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500] | 28975 | -0.231 | -0.0466 | No |
| 110 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 29649 | -0.401 | -0.0618 | No |
| 111 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 31294 | -0.850 | -0.1000 | No |
| 112 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32214 | -1.134 | -0.1165 | No |
| 113 | DUSP23 | dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480] | 32357 | -1.198 | -0.1115 | No |
| 114 | RPS26 | ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414] | 32771 | -1.359 | -0.1126 | No |
| 115 | STT3B | STT3 oligosaccharyltransferase complex catalytic subunit B [Source:HGNC Symbol;Acc:HGNC:30611] | 32819 | -1.379 | -0.1036 | No |
| 116 | LAG3 | lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476] | 33296 | -1.529 | -0.1052 | No |
| 117 | SLC26A2 | solute carrier family 26 member 2 [Source:HGNC Symbol;Acc:HGNC:10994] | 34472 | -2.074 | -0.1216 | No |
| 118 | ERO1A | endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280] | 35376 | -2.655 | -0.1264 | No |
| 119 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 35526 | -2.770 | -0.1099 | No |
| 120 | SLC9A3R2 | SLC9A3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076] | 35754 | -2.952 | -0.0942 | No |
| 121 | INSR | insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091] | 35921 | -3.091 | -0.0758 | No |
| 122 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36043 | -3.241 | -0.0550 | No |
| 123 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36354 | -3.546 | -0.0372 | No |
| 124 | CBR3 | carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] | 36405 | -3.594 | -0.0119 | No |
| 125 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36783 | -4.105 | 0.0083 | No |
