Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_BILE_ACID_METABOLISM |
| Enrichment Score (ES) | -0.55383176 |
| Normalized Enrichment Score (NES) | -1.1695478 |
| Nominal p-value | 0.1430193 |
| FDR q-value | 0.46441168 |
| FWER p-Value | 0.998 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ABCA1 | ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29] | 154 | 4.370 | 0.0263 | No |
| 2 | HAO1 | hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809] | 246 | 4.010 | 0.0518 | No |
| 3 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 365 | 3.555 | 0.0733 | No |
| 4 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 523 | 3.121 | 0.0908 | No |
| 5 | TFCP2L1 | transcription factor CP2 like 1 [Source:HGNC Symbol;Acc:HGNC:17925] | 624 | 2.959 | 0.1087 | No |
| 6 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 692 | 2.812 | 0.1265 | No |
| 7 | BCAR3 | BCAR3 adaptor protein, NSP family member [Source:HGNC Symbol;Acc:HGNC:973] | 753 | 2.692 | 0.1436 | No |
| 8 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 852 | 2.588 | 0.1590 | No |
| 9 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1104 | 2.188 | 0.1675 | No |
| 10 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 1668 | 1.672 | 0.1639 | No |
| 11 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 2062 | 1.393 | 0.1630 | No |
| 12 | CH25H | cholesterol 25-hydroxylase [Source:HGNC Symbol;Acc:HGNC:1907] | 2295 | 1.243 | 0.1654 | No |
| 13 | RXRA | retinoid X receptor alpha [Source:HGNC Symbol;Acc:HGNC:10477] | 2696 | 1.031 | 0.1617 | No |
| 14 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 3140 | 0.851 | 0.1557 | No |
| 15 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 3259 | 0.800 | 0.1581 | No |
| 16 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 3324 | 0.772 | 0.1617 | No |
| 17 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 3347 | 0.760 | 0.1664 | No |
| 18 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 5120 | 0.196 | 0.1198 | No |
| 19 | PECR | peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281] | 5343 | 0.153 | 0.1149 | No |
| 20 | PEX11G | peroxisomal biogenesis factor 11 gamma [Source:HGNC Symbol;Acc:HGNC:20208] | 5550 | 0.153 | 0.1104 | No |
| 21 | NR0B2 | nuclear receptor subfamily 0 group B member 2 [Source:HGNC Symbol;Acc:HGNC:7961] | 5637 | 0.153 | 0.1092 | No |
| 22 | PEX16 | peroxisomal biogenesis factor 16 [Source:HGNC Symbol;Acc:HGNC:8857] | 5787 | 0.107 | 0.1059 | No |
| 23 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 6067 | 0.021 | 0.0985 | No |
| 24 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 7793 | 0.000 | 0.0518 | No |
| 25 | ALDH8A1 | aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471] | 8502 | 0.000 | 0.0327 | No |
| 26 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9518 | 0.000 | 0.0052 | No |
| 27 | SLC23A1 | solute carrier family 23 member 1 [Source:HGNC Symbol;Acc:HGNC:10974] | 9725 | 0.000 | -0.0003 | No |
| 28 | APOA1 | apolipoprotein A1 [Source:HGNC Symbol;Acc:HGNC:600] | 10021 | 0.000 | -0.0083 | No |
| 29 | NEDD4 | NEDD4 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7727] | 10368 | 0.000 | -0.0177 | No |
| 30 | AKR1D1 | aldo-keto reductase family 1 member D1 [Source:HGNC Symbol;Acc:HGNC:388] | 11483 | 0.000 | -0.0478 | No |
| 31 | AGXT | alanine--glyoxylate and serine--pyruvate aminotransferase [Source:HGNC Symbol;Acc:HGNC:341] | 12123 | 0.000 | -0.0651 | No |
| 32 | CYP39A1 | cytochrome P450 family 39 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:17449] | 12327 | 0.000 | -0.0706 | No |
| 33 | HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5217] | 12465 | 0.000 | -0.0743 | No |
| 34 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12583 | 0.000 | -0.0774 | No |
| 35 | RBP1 | retinol binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9919] | 12741 | 0.000 | -0.0817 | No |
| 36 | CYP8B1 | cytochrome P450 family 8 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2653] | 15365 | 0.000 | -0.1526 | No |
| 37 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15724 | 0.000 | -0.1623 | No |
| 38 | DIO2 | iodothyronine deiodinase 2 [Source:HGNC Symbol;Acc:HGNC:2884] | 15725 | 0.000 | -0.1623 | No |
| 39 | AR | androgen receptor [Source:HGNC Symbol;Acc:HGNC:644] | 15988 | 0.000 | -0.1694 | No |
| 40 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 16080 | 0.000 | -0.1718 | No |
| 41 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17756 | 0.000 | -0.2171 | No |
| 42 | OPTN | optineurin [Source:HGNC Symbol;Acc:HGNC:17142] | 18013 | 0.000 | -0.2241 | No |
| 43 | BMP6 | bone morphogenetic protein 6 [Source:HGNC Symbol;Acc:HGNC:1073] | 19081 | 0.000 | -0.2529 | No |
| 44 | HSD17B6 | hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316] | 19800 | 0.000 | -0.2723 | No |
| 45 | NR1H4 | nuclear receptor subfamily 1 group H member 4 [Source:HGNC Symbol;Acc:HGNC:7967] | 20010 | 0.000 | -0.2780 | No |
| 46 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 20785 | 0.000 | -0.2989 | No |
| 47 | SULT1B1 | sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845] | 21101 | 0.000 | -0.3074 | No |
| 48 | PIPOX | pipecolic acid and sarcosine oxidase [Source:HGNC Symbol;Acc:HGNC:17804] | 22015 | 0.000 | -0.3321 | No |
| 49 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 22860 | 0.000 | -0.3549 | No |
| 50 | CYP46A1 | cytochrome P450 family 46 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2641] | 23105 | 0.000 | -0.3615 | No |
| 51 | SLC22A18 | solute carrier family 22 member 18 [Source:HGNC Symbol;Acc:HGNC:10964] | 23962 | 0.000 | -0.3847 | No |
| 52 | ABCA6 | ATP binding cassette subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:36] | 24065 | 0.000 | -0.3874 | No |
| 53 | ABCA4 | ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34] | 24068 | 0.000 | -0.3875 | No |
| 54 | ABCA9 | ATP binding cassette subfamily A member 9 [Source:HGNC Symbol;Acc:HGNC:39] | 24069 | 0.000 | -0.3875 | No |
| 55 | SLCO1A2 | solute carrier organic anion transporter family member 1A2 [Source:HGNC Symbol;Acc:HGNC:10956] | 24119 | 0.000 | -0.3888 | No |
| 56 | BBOX1 | gamma-butyrobetaine hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:964] | 25621 | 0.000 | -0.4294 | No |
| 57 | CYP7B1 | cytochrome P450 family 7 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2652] | 25941 | 0.000 | -0.4380 | No |
| 58 | CYP7A1 | cytochrome P450 family 7 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2651] | 25964 | 0.000 | -0.4386 | No |
| 59 | ABCG8 | ATP binding cassette subfamily G member 8 [Source:HGNC Symbol;Acc:HGNC:13887] | 28123 | 0.000 | -0.4970 | No |
| 60 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 28452 | -0.081 | -0.5053 | No |
| 61 | PEX19 | peroxisomal biogenesis factor 19 [Source:HGNC Symbol;Acc:HGNC:9713] | 28569 | -0.116 | -0.5076 | No |
| 62 | ABCA8 | ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38] | 28697 | -0.152 | -0.5100 | No |
| 63 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 28756 | -0.169 | -0.5104 | No |
| 64 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 29599 | -0.387 | -0.5305 | No |
| 65 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 29722 | -0.411 | -0.5309 | No |
| 66 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 29729 | -0.412 | -0.5282 | No |
| 67 | PHYH | phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940] | 30031 | -0.492 | -0.5329 | No |
| 68 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 30358 | -0.568 | -0.5378 | No |
| 69 | PEX1 | peroxisomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8850] | 30652 | -0.646 | -0.5412 | No |
| 70 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 30724 | -0.665 | -0.5385 | No |
| 71 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 30752 | -0.672 | -0.5345 | No |
| 72 | SOAT2 | sterol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:11178] | 31061 | -0.770 | -0.5375 | No |
| 73 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 31257 | -0.835 | -0.5369 | No |
| 74 | EFHC1 | EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16406] | 31470 | -0.883 | -0.5365 | No |
| 75 | KLF1 | Kruppel like factor 1 [Source:HGNC Symbol;Acc:HGNC:6345] | 31536 | -0.907 | -0.5320 | No |
| 76 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 32326 | -1.186 | -0.5450 | Yes |
| 77 | GNMT | glycine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:4415] | 32652 | -1.309 | -0.5447 | Yes |
| 78 | PEX26 | peroxisomal biogenesis factor 26 [Source:HGNC Symbol;Acc:HGNC:22965] | 32750 | -1.348 | -0.5379 | Yes |
| 79 | PNPLA8 | patatin like phospholipase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28900] | 32876 | -1.414 | -0.5315 | Yes |
| 80 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 33053 | -1.489 | -0.5259 | Yes |
| 81 | SLC27A5 | solute carrier family 27 member 5 [Source:HGNC Symbol;Acc:HGNC:10999] | 33091 | -1.503 | -0.5164 | Yes |
| 82 | NPC1 | NPC intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7897] | 33122 | -1.516 | -0.5066 | Yes |
| 83 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 33408 | -1.558 | -0.5035 | Yes |
| 84 | ABCG4 | ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884] | 33592 | -1.643 | -0.4970 | Yes |
| 85 | NUDT12 | nudix hydrolase 12 [Source:HGNC Symbol;Acc:HGNC:18826] | 33848 | -1.754 | -0.4917 | Yes |
| 86 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 33873 | -1.764 | -0.4800 | Yes |
| 87 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 34326 | -2.006 | -0.4783 | Yes |
| 88 | ABCA2 | ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32] | 34383 | -2.021 | -0.4657 | Yes |
| 89 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 34442 | -2.058 | -0.4529 | Yes |
| 90 | NR3C2 | nuclear receptor subfamily 3 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7979] | 34476 | -2.077 | -0.4394 | Yes |
| 91 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 35045 | -2.388 | -0.4381 | Yes |
| 92 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35081 | -2.410 | -0.4223 | Yes |
| 93 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 35151 | -2.472 | -0.4069 | Yes |
| 94 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35191 | -2.505 | -0.3905 | Yes |
| 95 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35301 | -2.587 | -0.3754 | Yes |
| 96 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 35344 | -2.620 | -0.3583 | Yes |
| 97 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35507 | -2.751 | -0.3435 | Yes |
| 98 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35588 | -2.834 | -0.3260 | Yes |
| 99 | PAOX | polyamine oxidase [Source:HGNC Symbol;Acc:HGNC:20837] | 35730 | -2.930 | -0.3094 | Yes |
| 100 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 35766 | -2.958 | -0.2897 | Yes |
| 101 | PXMP2 | peroxisomal membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:9716] | 35801 | -2.992 | -0.2698 | Yes |
| 102 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 35847 | -3.028 | -0.2499 | Yes |
| 103 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 36037 | -3.234 | -0.2325 | Yes |
| 104 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36122 | -3.318 | -0.2116 | Yes |
| 105 | FDXR | ferredoxin reductase [Source:HGNC Symbol;Acc:HGNC:3642] | 36245 | -3.446 | -0.1909 | Yes |
| 106 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36715 | -3.998 | -0.1758 | Yes |
| 107 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 36742 | -4.042 | -0.1483 | Yes |
| 108 | HACL1 | 2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856] | 36773 | -4.082 | -0.1207 | Yes |
| 109 | ABCA5 | ATP binding cassette subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:35] | 36809 | -4.132 | -0.0928 | Yes |
| 110 | PFKM | phosphofructokinase, muscle [Source:HGNC Symbol;Acc:HGNC:8877] | 37016 | -4.697 | -0.0657 | Yes |
| 111 | CYP27A1 | cytochrome P450 family 27 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2605] | 37045 | -4.808 | -0.0329 | Yes |
| 112 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37064 | -4.899 | 0.0007 | Yes |
