Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_INTERFERON_ALPHA_RESPONSE |
| Enrichment Score (ES) | 0.8541268 |
| Normalized Enrichment Score (NES) | 2.157931 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 19 | 4.971 | 0.0204 | Yes |
| 2 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 34 | 4.950 | 0.0408 | Yes |
| 3 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 53 | 4.874 | 0.0608 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 54 | 4.870 | 0.0813 | Yes |
| 5 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 59 | 4.856 | 0.1016 | Yes |
| 6 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 63 | 4.848 | 0.1219 | Yes |
| 7 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 73 | 4.798 | 0.1419 | Yes |
| 8 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 96 | 4.689 | 0.1610 | Yes |
| 9 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.1803 | Yes |
| 10 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 105 | 4.608 | 0.1997 | Yes |
| 11 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 106 | 4.607 | 0.2190 | Yes |
| 12 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 117 | 4.553 | 0.2379 | Yes |
| 13 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 121 | 4.521 | 0.2568 | Yes |
| 14 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 140 | 4.434 | 0.2750 | Yes |
| 15 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 143 | 4.411 | 0.2935 | Yes |
| 16 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 150 | 4.382 | 0.3118 | Yes |
| 17 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 182 | 4.222 | 0.3287 | Yes |
| 18 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 207 | 4.163 | 0.3455 | Yes |
| 19 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 217 | 4.103 | 0.3625 | Yes |
| 20 | PROCR | protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] | 220 | 4.091 | 0.3797 | Yes |
| 21 | TRAFD1 | TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808] | 240 | 4.032 | 0.3961 | Yes |
| 22 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 270 | 3.926 | 0.4119 | Yes |
| 23 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 272 | 3.915 | 0.4283 | Yes |
| 24 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 287 | 3.852 | 0.4441 | Yes |
| 25 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 290 | 3.839 | 0.4602 | Yes |
| 26 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 301 | 3.811 | 0.4760 | Yes |
| 27 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 308 | 3.777 | 0.4917 | Yes |
| 28 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 320 | 3.719 | 0.5070 | Yes |
| 29 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 326 | 3.698 | 0.5224 | Yes |
| 30 | UBA7 | ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471] | 335 | 3.649 | 0.5376 | Yes |
| 31 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 361 | 3.577 | 0.5519 | Yes |
| 32 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 368 | 3.551 | 0.5667 | Yes |
| 33 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 371 | 3.546 | 0.5815 | Yes |
| 34 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 436 | 3.395 | 0.5941 | Yes |
| 35 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 457 | 3.321 | 0.6075 | Yes |
| 36 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 497 | 3.222 | 0.6200 | Yes |
| 37 | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 511 | 3.173 | 0.6330 | Yes |
| 38 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 635 | 2.926 | 0.6420 | Yes |
| 39 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 640 | 2.917 | 0.6541 | Yes |
| 40 | MOV10 | Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200] | 663 | 2.881 | 0.6657 | Yes |
| 41 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 690 | 2.816 | 0.6768 | Yes |
| 42 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 720 | 2.747 | 0.6876 | Yes |
| 43 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 752 | 2.696 | 0.6981 | Yes |
| 44 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 778 | 2.636 | 0.7085 | Yes |
| 45 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 788 | 2.615 | 0.7192 | Yes |
| 46 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 846 | 2.601 | 0.7286 | Yes |
| 47 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 877 | 2.551 | 0.7385 | Yes |
| 48 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 929 | 2.466 | 0.7475 | Yes |
| 49 | OGFR | opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768] | 956 | 2.423 | 0.7570 | Yes |
| 50 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 977 | 2.389 | 0.7665 | Yes |
| 51 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 1008 | 2.327 | 0.7755 | Yes |
| 52 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 1010 | 2.323 | 0.7852 | Yes |
| 53 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 1030 | 2.281 | 0.7943 | Yes |
| 54 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 1071 | 2.234 | 0.8026 | Yes |
| 55 | IRF9 | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131] | 1236 | 2.021 | 0.8067 | Yes |
| 56 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 1251 | 2.003 | 0.8147 | Yes |
| 57 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 1261 | 1.989 | 0.8229 | Yes |
| 58 | CMTR1 | cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077] | 1316 | 1.932 | 0.8295 | Yes |
| 59 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1318 | 1.930 | 0.8376 | Yes |
| 60 | IRF1 | interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116] | 1338 | 1.913 | 0.8451 | Yes |
| 61 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1426 | 1.810 | 0.8504 | Yes |
| 62 | TRIM26 | tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962] | 1608 | 1.751 | 0.8529 | Yes |
| 63 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 1818 | 1.560 | 0.8538 | Yes |
| 64 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 2025 | 1.407 | 0.8541 | Yes |
| 65 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 2262 | 1.259 | 0.8530 | No |
| 66 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 2437 | 1.154 | 0.8532 | No |
| 67 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2591 | 1.095 | 0.8537 | No |
| 68 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 2911 | 0.938 | 0.8490 | No |
| 69 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 3294 | 0.784 | 0.8420 | No |
| 70 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 3329 | 0.771 | 0.8443 | No |
| 71 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3718 | 0.628 | 0.8364 | No |
| 72 | NCOA7 | nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081] | 6122 | 0.007 | 0.7715 | No |
| 73 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6995 | 0.000 | 0.7479 | No |
| 74 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8624 | 0.000 | 0.7039 | No |
| 75 | BATF2 | basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] | 8750 | 0.000 | 0.7005 | No |
| 76 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9109 | 0.000 | 0.6909 | No |
| 77 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10411 | 0.000 | 0.6557 | No |
| 78 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11431 | 0.000 | 0.6282 | No |
| 79 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12349 | 0.000 | 0.6034 | No |
| 80 | IL4R | interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015] | 13756 | 0.000 | 0.5654 | No |
| 81 | TRIM5 | tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276] | 17766 | 0.000 | 0.4570 | No |
| 82 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18917 | 0.000 | 0.4259 | No |
| 83 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19341 | 0.000 | 0.4145 | No |
| 84 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20701 | 0.000 | 0.3777 | No |
| 85 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21587 | 0.000 | 0.3538 | No |
| 86 | NUB1 | negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623] | 28693 | -0.151 | 0.1624 | No |
| 87 | ELF1 | E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316] | 29398 | -0.334 | 0.1448 | No |
| 88 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 29512 | -0.367 | 0.1432 | No |
| 89 | IRF2 | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117] | 30853 | -0.696 | 0.1100 | No |
| 90 | SLC25A28 | solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472] | 31007 | -0.746 | 0.1090 | No |
| 91 | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158] | 31452 | -0.876 | 0.1006 | No |
| 92 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32214 | -1.134 | 0.0848 | No |
| 93 | MVB12A | multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153] | 32387 | -1.211 | 0.0853 | No |
| 94 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32684 | -1.319 | 0.0828 | No |
| 95 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 33542 | -1.617 | 0.0665 | No |
| 96 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35949 | -3.129 | 0.0146 | No |
| 97 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36601 | -3.861 | 0.0132 | No |
