Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PANCREAS_BETA_CELLS |
| Enrichment Score (ES) | -0.64994854 |
| Normalized Enrichment Score (NES) | -1.2229575 |
| Nominal p-value | 0.14993481 |
| FDR q-value | 0.33998787 |
| FWER p-Value | 0.971 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SRP9 | signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304] | 1698 | 1.644 | 0.0250 | No |
| 2 | STXBP1 | syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444] | 2090 | 1.370 | 0.0735 | No |
| 3 | SRPRB | SRP receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:24085] | 2908 | 0.938 | 0.0918 | No |
| 4 | SEC11A | SEC11 homolog A, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:17718] | 4533 | 0.356 | 0.0633 | No |
| 5 | AKT3 | AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393] | 6069 | 0.021 | 0.0228 | No |
| 6 | SCGN | secretagogin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:HGNC:16941] | 6355 | 0.000 | 0.0151 | No |
| 7 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10443 | 0.000 | -0.0952 | No |
| 8 | G6PC2 | glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906] | 12263 | 0.000 | -0.1443 | No |
| 9 | SST | somatostatin [Source:HGNC Symbol;Acc:HGNC:11329] | 12310 | 0.000 | -0.1455 | No |
| 10 | SYT13 | synaptotagmin 13 [Source:HGNC Symbol;Acc:HGNC:14962] | 13588 | 0.000 | -0.1800 | No |
| 11 | PAX4 | paired box 4 [Source:HGNC Symbol;Acc:HGNC:8618] | 14757 | 0.000 | -0.2115 | No |
| 12 | DCX | doublecortin [Source:HGNC Symbol;Acc:HGNC:2714] | 15934 | 0.000 | -0.2432 | No |
| 13 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16174 | 0.000 | -0.2497 | No |
| 14 | PCSK1 | proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743] | 16175 | 0.000 | -0.2497 | No |
| 15 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16866 | 0.000 | -0.2683 | No |
| 16 | GCK | glucokinase [Source:HGNC Symbol;Acc:HGNC:4195] | 16868 | 0.000 | -0.2683 | No |
| 17 | HNF1A | HNF1 homeobox A [Source:HGNC Symbol;Acc:HGNC:11621] | 17558 | 0.000 | -0.2869 | No |
| 18 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17710 | 0.000 | -0.2910 | No |
| 19 | DPP4 | dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] | 17911 | 0.000 | -0.2964 | No |
| 20 | NKX2-2 | NK2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7835] | 19214 | 0.000 | -0.3316 | No |
| 21 | IAPP | islet amyloid polypeptide [Source:HGNC Symbol;Acc:HGNC:5329] | 19267 | 0.000 | -0.3330 | No |
| 22 | NEUROD1 | neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762] | 19273 | 0.000 | -0.3331 | No |
| 23 | NEUROG3 | neurogenin 3 [Source:HGNC Symbol;Acc:HGNC:13806] | 19390 | 0.000 | -0.3362 | No |
| 24 | FOXA2 | forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022] | 20695 | 0.000 | -0.3714 | No |
| 25 | NKX6-1 | NK6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7839] | 25292 | 0.000 | -0.4955 | No |
| 26 | PDX1 | pancreatic and duodenal homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6107] | 26089 | 0.000 | -0.5169 | No |
| 27 | INSM1 | INSM transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:6090] | 26743 | 0.000 | -0.5346 | No |
| 28 | ISL1 | ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132] | 26961 | 0.000 | -0.5404 | No |
| 29 | SLC2A2 | solute carrier family 2 member 2 [Source:HGNC Symbol;Acc:HGNC:11006] | 28141 | 0.000 | -0.5722 | No |
| 30 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 28154 | 0.000 | -0.5726 | No |
| 31 | ELP4 | elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:1171] | 28510 | -0.097 | -0.5780 | No |
| 32 | SPCS1 | signal peptidase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23401] | 28577 | -0.120 | -0.5746 | No |
| 33 | SRP14 | signal recognition particle 14 [Source:HGNC Symbol;Acc:HGNC:11299] | 28656 | -0.141 | -0.5706 | No |
| 34 | PAK3 | p21 (RAC1) activated kinase 3 [Source:HGNC Symbol;Acc:HGNC:8592] | 30812 | -0.683 | -0.5993 | Yes |
| 35 | PKLR | pyruvate kinase L/R [Source:HGNC Symbol;Acc:HGNC:9020] | 32688 | -1.321 | -0.5930 | Yes |
| 36 | VDR | vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679] | 33110 | -1.509 | -0.5394 | Yes |
| 37 | LMO2 | LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642] | 33830 | -1.742 | -0.4838 | Yes |
| 38 | MAFB | MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408] | 36824 | -4.172 | -0.3848 | Yes |
| 39 | PAX6 | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | 36931 | -4.440 | -0.1965 | Yes |
| 40 | FOXO1 | forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819] | 37007 | -4.660 | 0.0022 | Yes |
