Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PEROXISOME |
| Enrichment Score (ES) | -0.54640836 |
| Normalized Enrichment Score (NES) | -1.1433022 |
| Nominal p-value | 0.19906868 |
| FDR q-value | 0.5427921 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CACNA1B | calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389] | 327 | 3.693 | 0.0180 | No |
| 2 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 460 | 3.318 | 0.0385 | No |
| 3 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433] | 502 | 3.205 | 0.0607 | No |
| 4 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 523 | 3.121 | 0.0828 | No |
| 5 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 852 | 2.588 | 0.0928 | No |
| 6 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 1066 | 2.239 | 0.1033 | No |
| 7 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1422 | 1.815 | 0.1069 | No |
| 8 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 1589 | 1.771 | 0.1152 | No |
| 9 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1594 | 1.765 | 0.1280 | No |
| 10 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 1668 | 1.672 | 0.1381 | No |
| 11 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 1804 | 1.568 | 0.1459 | No |
| 12 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 2062 | 1.393 | 0.1490 | No |
| 13 | ABCB9 | ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50] | 2772 | 0.999 | 0.1371 | No |
| 14 | CNBP | CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164] | 2795 | 0.985 | 0.1437 | No |
| 15 | VPS4B | vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895] | 2894 | 0.947 | 0.1479 | No |
| 16 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 3114 | 0.863 | 0.1483 | No |
| 17 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 3259 | 0.800 | 0.1502 | No |
| 18 | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435] | 3343 | 0.763 | 0.1535 | No |
| 19 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 3347 | 0.760 | 0.1589 | No |
| 20 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 3747 | 0.620 | 0.1527 | No |
| 21 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] | 3804 | 0.602 | 0.1555 | No |
| 22 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 4126 | 0.494 | 0.1504 | No |
| 23 | SLC25A19 | solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409] | 4147 | 0.488 | 0.1534 | No |
| 24 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 4651 | 0.327 | 0.1422 | No |
| 25 | PEX5 | peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719] | 4725 | 0.308 | 0.1425 | No |
| 26 | FIS1 | fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689] | 4827 | 0.279 | 0.1418 | No |
| 27 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 5057 | 0.213 | 0.1371 | No |
| 28 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 5120 | 0.196 | 0.1369 | No |
| 29 | PEX14 | peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856] | 5991 | 0.042 | 0.1137 | No |
| 30 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 6067 | 0.021 | 0.1118 | No |
| 31 | PABPC1 | poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554] | 6144 | 0.001 | 0.1097 | No |
| 32 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 7793 | 0.000 | 0.0652 | No |
| 33 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 7811 | 0.000 | 0.0647 | No |
| 34 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9518 | 0.000 | 0.0186 | No |
| 35 | ESR2 | estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468] | 11913 | 0.000 | -0.0461 | No |
| 36 | STS | steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425] | 12318 | 0.000 | -0.0571 | No |
| 37 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12583 | 0.000 | -0.0642 | No |
| 38 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209] | 14319 | 0.000 | -0.1111 | No |
| 39 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15665 | 0.000 | -0.1475 | No |
| 40 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15724 | 0.000 | -0.1490 | No |
| 41 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17756 | 0.000 | -0.2039 | No |
| 42 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 17829 | 0.000 | -0.2059 | No |
| 43 | UGT2B17 | UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547] | 18163 | 0.000 | -0.2149 | No |
| 44 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 20785 | 0.000 | -0.2858 | No |
| 45 | CRABP2 | cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339] | 21076 | 0.000 | -0.2936 | No |
| 46 | CRABP1 | cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338] | 21077 | 0.000 | -0.2936 | No |
| 47 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 21268 | 0.000 | -0.2987 | No |
| 48 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 21955 | 0.000 | -0.3173 | No |
| 49 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 22860 | 0.000 | -0.3417 | No |
| 50 | FABP6 | fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561] | 24095 | 0.000 | -0.3751 | No |
| 51 | ALB | albumin [Source:HGNC Symbol;Acc:HGNC:399] | 24517 | 0.000 | -0.3865 | No |
| 52 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 28154 | 0.000 | -0.4848 | No |
| 53 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 28452 | -0.081 | -0.4922 | No |
| 54 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 28514 | -0.098 | -0.4931 | No |
| 55 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 28756 | -0.169 | -0.4984 | No |
| 56 | RDH11 | retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] | 29234 | -0.298 | -0.5092 | No |
| 57 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 29599 | -0.387 | -0.5162 | No |
| 58 | CTBP1 | C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494] | 29623 | -0.396 | -0.5139 | No |
| 59 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 29722 | -0.411 | -0.5136 | No |
| 60 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 29729 | -0.412 | -0.5108 | No |
| 61 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29757 | -0.420 | -0.5085 | No |
| 62 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 30358 | -0.568 | -0.5205 | No |
| 63 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 30752 | -0.672 | -0.5263 | No |
| 64 | HRAS | HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173] | 30836 | -0.689 | -0.5235 | No |
| 65 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 31645 | -0.943 | -0.5385 | No |
| 66 | SIAH1 | siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857] | 31938 | -1.038 | -0.5389 | Yes |
| 67 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 31973 | -1.053 | -0.5321 | Yes |
| 68 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 32086 | -1.102 | -0.5272 | Yes |
| 69 | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104] | 32218 | -1.135 | -0.5225 | Yes |
| 70 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 32241 | -1.143 | -0.5147 | Yes |
| 71 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 32326 | -1.186 | -0.5084 | Yes |
| 72 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 33031 | -1.478 | -0.5167 | Yes |
| 73 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 33053 | -1.489 | -0.5065 | Yes |
| 74 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 33064 | -1.494 | -0.4959 | Yes |
| 75 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 33066 | -1.494 | -0.4850 | Yes |
| 76 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 33408 | -1.558 | -0.4829 | Yes |
| 77 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 33464 | -1.583 | -0.4729 | Yes |
| 78 | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] | 33794 | -1.729 | -0.4693 | Yes |
| 79 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 33873 | -1.764 | -0.4586 | Yes |
| 80 | CADM1 | cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951] | 34002 | -1.830 | -0.4487 | Yes |
| 81 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 34326 | -2.006 | -0.4429 | Yes |
| 82 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 34442 | -2.058 | -0.4310 | Yes |
| 83 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 34560 | -2.126 | -0.4188 | Yes |
| 84 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35081 | -2.410 | -0.4153 | Yes |
| 85 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35191 | -2.505 | -0.4001 | Yes |
| 86 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35257 | -2.555 | -0.3833 | Yes |
| 87 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35301 | -2.587 | -0.3656 | Yes |
| 88 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35429 | -2.680 | -0.3496 | Yes |
| 89 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35507 | -2.751 | -0.3317 | Yes |
| 90 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 35576 | -2.822 | -0.3130 | Yes |
| 91 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35588 | -2.834 | -0.2927 | Yes |
| 92 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.2730 | Yes |
| 93 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 35766 | -2.958 | -0.2550 | Yes |
| 94 | DLG4 | discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903] | 35815 | -2.999 | -0.2345 | Yes |
| 95 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 35847 | -3.028 | -0.2133 | Yes |
| 96 | ELOVL5 | ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] | 35894 | -3.064 | -0.1923 | Yes |
| 97 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 36037 | -3.234 | -0.1727 | Yes |
| 98 | ABCC5 | ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56] | 36254 | -3.460 | -0.1534 | Yes |
| 99 | ABCB4 | ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] | 36265 | -3.472 | -0.1284 | Yes |
| 100 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36507 | -3.704 | -0.1080 | Yes |
| 101 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36715 | -3.998 | -0.0846 | Yes |
| 102 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 36742 | -4.042 | -0.0559 | Yes |
| 103 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36776 | -4.085 | -0.0271 | Yes |
| 104 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37064 | -4.899 | 0.0007 | Yes |
