Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.4145489 |
| Normalized Enrichment Score (NES) | 0.9322269 |
| Nominal p-value | 0.5925926 |
| FDR q-value | 0.7512818 |
| FWER p-Value | 0.98 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 359 | 3.593 | 0.0511 | Yes |
| 2 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 438 | 3.391 | 0.1063 | Yes |
| 3 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 460 | 3.318 | 0.1618 | Yes |
| 4 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 516 | 3.159 | 0.2138 | Yes |
| 5 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 990 | 2.344 | 0.2406 | Yes |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1104 | 2.188 | 0.2746 | Yes |
| 7 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 1124 | 2.160 | 0.3106 | Yes |
| 8 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1422 | 1.815 | 0.3332 | Yes |
| 9 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1756 | 1.602 | 0.3513 | Yes |
| 10 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 1916 | 1.497 | 0.3723 | Yes |
| 11 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1974 | 1.451 | 0.3954 | Yes |
| 12 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 2796 | 0.985 | 0.3898 | Yes |
| 13 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 3249 | 0.803 | 0.3912 | Yes |
| 14 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 3346 | 0.761 | 0.4015 | Yes |
| 15 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 3512 | 0.704 | 0.4089 | Yes |
| 16 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 3911 | 0.566 | 0.4078 | Yes |
| 17 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 3997 | 0.537 | 0.4145 | Yes |
| 18 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 4976 | 0.238 | 0.3922 | No |
| 19 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 5212 | 0.168 | 0.3887 | No |
| 20 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 5654 | 0.151 | 0.3793 | No |
| 21 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9346 | 0.000 | 0.2797 | No |
| 22 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 11811 | 0.000 | 0.2132 | No |
| 23 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17711 | 0.000 | 0.0539 | No |
| 24 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17897 | 0.000 | 0.0489 | No |
| 25 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19033 | 0.000 | 0.0183 | No |
| 26 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 27817 | 0.000 | -0.2188 | No |
| 27 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 28916 | -0.215 | -0.2448 | No |
| 28 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 29272 | -0.303 | -0.2493 | No |
| 29 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 29467 | -0.353 | -0.2486 | No |
| 30 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 29562 | -0.376 | -0.2447 | No |
| 31 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 29602 | -0.389 | -0.2392 | No |
| 32 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 29737 | -0.414 | -0.2358 | No |
| 33 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30103 | -0.511 | -0.2370 | No |
| 34 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 30358 | -0.568 | -0.2343 | No |
| 35 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 30423 | -0.587 | -0.2261 | No |
| 36 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 30888 | -0.708 | -0.2266 | No |
| 37 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 31292 | -0.849 | -0.2232 | No |
| 38 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 31934 | -1.036 | -0.2229 | No |
| 39 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 32229 | -1.140 | -0.2116 | No |
| 40 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 32349 | -1.193 | -0.1947 | No |
| 41 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 32421 | -1.221 | -0.1759 | No |
| 42 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 32663 | -1.311 | -0.1603 | No |
| 43 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 32669 | -1.314 | -0.1382 | No |
| 44 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 32760 | -1.353 | -0.1177 | No |
| 45 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35124 | -2.440 | -0.1403 | No |
| 46 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35191 | -2.505 | -0.0997 | No |
| 47 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 35711 | -2.911 | -0.0645 | No |
| 48 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 35803 | -2.995 | -0.0163 | No |
| 49 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 35835 | -3.015 | 0.0339 | No |
