Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetBMI1_DN.V1_UP
Enrichment Score (ES)0.4373828
Normalized Enrichment Score (NES)1.1882234
Nominal p-value0.030612245
FDR q-value0.1934221
FWER p-Value0.77
Table: GSEA Results Summary



Fig 1: Enrichment plot: BMI1_DN.V1_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PMEPA1prostate transmembrane protein, androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:14107]84.8530.0366Yes
2EDN1endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176]474.2370.0677Yes
3C3AR1complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319]624.0470.0980Yes
4ITGA5integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141]813.8040.1264Yes
5VEGFCvascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682]983.7080.1541Yes
6ABCA1ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29]1773.2200.1764Yes
7LIFLIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596]1933.1440.1998Yes
8ACTA2actin alpha 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:130]2173.0070.2220Yes
9CHST11carbohydrate sulfotransferase 11 [Source:HGNC Symbol;Acc:HGNC:17422]2482.8640.2429Yes
10FURINfurin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568]3582.5060.2590Yes
11CRISPLD2cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]4072.4010.2759Yes
12PIEZO1piezo type mechanosensitive ion channel component 1 [Source:HGNC Symbol;Acc:HGNC:28993]4372.3160.2927Yes
13FLNBfilamin B [Source:HGNC Symbol;Acc:HGNC:3755]4392.3120.3102Yes
14FZD5frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043]4732.2280.3262Yes
15GPRC5AG protein-coupled receptor class C group 5 member A [Source:HGNC Symbol;Acc:HGNC:9836]5922.0220.3383Yes
16SLC1A5solute carrier family 1 member 5 [Source:HGNC Symbol;Acc:HGNC:10943]6171.9890.3528Yes
17GFPT2glutamine-fructose-6-phosphate transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4242]7111.8460.3643Yes
18TNFAIP6TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898]8031.7350.3750Yes
19SLC2A1solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005]9081.6160.3844Yes
20TMEM62transmembrane protein 62 [Source:HGNC Symbol;Acc:HGNC:26269]9171.6010.3963Yes
21NRP2neuropilin 2 [Source:HGNC Symbol;Acc:HGNC:8005]9641.5620.4069Yes
22TAP1transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]10601.4760.4156Yes
23LCP1lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528]12041.3770.4221Yes
24FAPfibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590]14851.1890.4236Yes
25SLC7A5solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063]15371.1610.4310Yes
26SLC52A2solute carrier family 52 member 2 [Source:HGNC Symbol;Acc:HGNC:30224]18950.9960.4289Yes
27CD82CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210]20870.9170.4307Yes
28SLC1A4solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942]22080.8750.4341Yes
29HBEGFheparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059]23260.8330.4372Yes
30CSF1colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432]25480.7630.4370Yes
31FJX1four-jointed box kinase 1 [Source:HGNC Symbol;Acc:HGNC:17166]27360.7150.4374Yes
32DHRS3dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693]38780.4430.4099No
33AGRNagrin [Source:HGNC Symbol;Acc:HGNC:329]38910.4410.4129No
34ASPHaspartate beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:757]39130.4370.4156No
35BST1bone marrow stromal cell antigen 1 [Source:HGNC Symbol;Acc:HGNC:1118]41390.3970.4125No
36PODXLpodocalyxin like [Source:HGNC Symbol;Acc:HGNC:9171]46590.3000.4008No
37SLC19A1solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937]52220.2070.3871No
38TGFB2transforming growth factor beta 2 [Source:HGNC Symbol;Acc:HGNC:11768]54020.1770.3836No
39LRIG1leucine rich repeats and immunoglobulin like domains 1 [Source:HGNC Symbol;Acc:HGNC:17360]55420.1500.3810No
40TNFRSF8TNF receptor superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11923]55520.1490.3819No
41INHBAinhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066]59650.0910.3714No
42STX1Asyntaxin 1A [Source:HGNC Symbol;Acc:HGNC:11433]62500.0490.3641No
43B4GALNT1beta-1,4-N-acetyl-galactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4117]65060.0050.3573No
44CCL20C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619]66090.0000.3545No
45FGF21fibroblast growth factor 21 [Source:HGNC Symbol;Acc:HGNC:3678]71150.0000.3408No
46FGFR1fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688]73770.0000.3338No
47VANGL1VANGL planar cell polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:15512]82300.0000.3107No
48GREM1gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001]84410.0000.3050No
49PROP1PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455]85380.0000.3024No
50HOXB1homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111]90220.0000.2893No
51TNFSF9TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939]90570.0000.2884No
52VLDLRvery low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:12698]97340.0000.2701No
53TNFRSF9TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924]99930.0000.2631No
54PLATplasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051]101110.0000.2600No
55ADAM12ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190]101240.0000.2597No
56ACKR3atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692]112780.0000.2284No
57LRRC15leucine rich repeat containing 15 [Source:HGNC Symbol;Acc:HGNC:20818]115830.0000.2202No
58PTHLHparathyroid hormone like hormone [Source:HGNC Symbol;Acc:HGNC:9607]118160.0000.2139No
59PSG5pregnancy specific beta-1-glycoprotein 5 [Source:HGNC Symbol;Acc:HGNC:9522]120200.0000.2084No
60IGKCimmunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716]126480.0000.1915No
61VNN1vanin 1 [Source:HGNC Symbol;Acc:HGNC:12705]128830.0000.1851No
62TIE1tyrosine kinase with immunoglobulin like and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:11809]132000.0000.1766No
63GDF5growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220]135540.0000.1670No
64TAGLNtransgelin [Source:HGNC Symbol;Acc:HGNC:11553]139390.0000.1566No
65COL13A1collagen type XIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2190]156310.0000.1109No
66F3coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541]162410.0000.0944No
67DKK1dickkopf WNT signaling pathway inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:2891]164420.0000.0890No
68COL16A1collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193]165580.0000.0859No
69GALgalanin and GMAP prepropeptide [Source:HGNC Symbol;Acc:HGNC:4114]169660.0000.0748No
70TIMP3TIMP metallopeptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:11822]172040.0000.0684No
71CDCP1CUB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:24357]173420.0000.0647No
72GABREgamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085]173620.0000.0642No
73HAPLN1hyaluronan and proteoglycan link protein 1 [Source:HGNC Symbol;Acc:HGNC:2380]174710.0000.0613No
74SRPX2sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668]175730.0000.0585No
75MICAMHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:HGNC:7090]177320.0000.0543No
76MICBMHC class I polypeptide-related sequence B [Source:HGNC Symbol;Acc:HGNC:7091]177330.0000.0543No
77SEMA3Gsemaphorin 3G [Source:HGNC Symbol;Acc:HGNC:30400]179110.0000.0495No
78PAPPApappalysin 1 [Source:HGNC Symbol;Acc:HGNC:8602]179230.0000.0492No
79BDKRB2bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030]180100.0000.0468No
80BMP5bone morphogenetic protein 5 [Source:HGNC Symbol;Acc:HGNC:1072]191030.0000.0173No
81BMP4bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071]191050.0000.0173No
82MMP7matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174]191300.0000.0166No
83MMP3matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173]191370.0000.0165No
84CXCL1C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602]194880.0000.0070No
85TCIMtranscriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357]198830.000-0.0037No
86MMP15matrix metallopeptidase 15 [Source:HGNC Symbol;Acc:HGNC:7161]209340.000-0.0321No
87KRT17keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427]220950.000-0.0635No
88CCN3cellular communication network factor 3 [Source:HGNC Symbol;Acc:HGNC:7885]230770.000-0.0901No
89FOXP3forkhead box P3 [Source:HGNC Symbol;Acc:HGNC:6106]236690.000-0.1061No
90CPA4carboxypeptidase A4 [Source:HGNC Symbol;Acc:HGNC:15740]236930.000-0.1067No
91LAMB3laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490]239240.000-0.1129No
92CSF2colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434]247000.000-0.1339No
93LSAMPlimbic system associated membrane protein [Source:HGNC Symbol;Acc:HGNC:6705]249160.000-0.1397No
94CLDN1claudin 1 [Source:HGNC Symbol;Acc:HGNC:2032]250450.000-0.1432No
95HAS2hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819]251100.000-0.1449No
96MFAP5microfibril associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29673]257110.000-0.1611No
97PDCD1LG2programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731]257950.000-0.1634No
98ITGB8integrin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:6163]266490.000-0.1865No
99ITGB6integrin subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:6161]266520.000-0.1865No
100ITGA3integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]266550.000-0.1866No
101SLCO2A1solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955]268290.000-0.1913No
102FKRPfukutin related protein [Source:HGNC Symbol;Acc:HGNC:17997]27773-0.009-0.2167No
103ATF6activating transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:791]27814-0.019-0.2177No
104IL7Rinterleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024]27994-0.049-0.2221No
105CSPG5chondroitin sulfate proteoglycan 5 [Source:HGNC Symbol;Acc:HGNC:2467]28551-0.132-0.2362No
106SLC5A6solute carrier family 5 member 6 [Source:HGNC Symbol;Acc:HGNC:11041]28807-0.165-0.2418No
107NT5E5'-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021]28926-0.179-0.2437No
108ANXA3annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]29116-0.200-0.2473No
109TEKTEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724]29507-0.250-0.2559No
110TLCD3ATLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646]29537-0.255-0.2548No
111EPHA2EPH receptor A2 [Source:HGNC Symbol;Acc:HGNC:3386]29949-0.316-0.2635No
112ADGRE5adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]30527-0.405-0.2760No
113STC2stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374]30967-0.474-0.2843No
114CCND1cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582]31124-0.500-0.2848No
115KMT2Alysine methyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:7132]31625-0.592-0.2938No
116SLC29A2solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004]31868-0.641-0.2955No
117CSPG4chondroitin sulfate proteoglycan 4 [Source:HGNC Symbol;Acc:HGNC:2466]32118-0.692-0.2970No
118FESFES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657]32485-0.768-0.3011No
119POMT2protein O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:19743]32589-0.794-0.2978No
120TRIOtrio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]32667-0.815-0.2937No
121SLC2A6solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011]32918-0.880-0.2938No
122CTSScathepsin S [Source:HGNC Symbol;Acc:HGNC:2545]33059-0.915-0.2907No
123COL7A1collagen type VII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2214]33283-0.971-0.2894No
124INHBEinhibin subunit beta E [Source:HGNC Symbol;Acc:HGNC:24029]33702-1.093-0.2924No
125MFGE8milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036]33944-1.168-0.2900No
126ANPEPalanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]34032-1.201-0.2833No
127C2CD2LC2CD2 like [Source:HGNC Symbol;Acc:HGNC:29000]34508-1.384-0.2856No
128FADS3fatty acid desaturase 3 [Source:HGNC Symbol;Acc:HGNC:3576]34642-1.449-0.2783No
129PANX1pannexin 1 [Source:HGNC Symbol;Acc:HGNC:8599]35208-1.728-0.2804No
130LHFPL2LHFPL tetraspan subfamily member 2 [Source:HGNC Symbol;Acc:HGNC:6588]35250-1.758-0.2682No
131JAG1jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]35309-1.796-0.2562No
132KCNC4potassium voltage-gated channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:6236]35334-1.813-0.2431No
133SIRPAsignal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662]35545-1.941-0.2340No
134CHST3carbohydrate sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:1971]35686-2.045-0.2223No
135LRP5LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]35940-2.251-0.2121No
136CTNScystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:HGNC:2518]35957-2.263-0.1953No
137TMEM51transmembrane protein 51 [Source:HGNC Symbol;Acc:HGNC:25488]36019-2.311-0.1795No
138P3H3prolyl 3-hydroxylase 3 [Source:HGNC Symbol;Acc:HGNC:19318]36020-2.312-0.1619No
139SLCO4A1solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953]36057-2.343-0.1451No
140PLXNA2plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100]36242-2.527-0.1310No
141SLC29A1solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003]36525-2.874-0.1168No
142CLSPNclaspin [Source:HGNC Symbol;Acc:HGNC:19715]36538-2.886-0.0952No
143LTBP4latent transforming growth factor beta binding protein 4 [Source:HGNC Symbol;Acc:HGNC:6717]36540-2.893-0.0733No
144ATP13A2ATPase cation transporting 13A2 [Source:HGNC Symbol;Acc:HGNC:30213]36826-3.460-0.0548No
145ITGA4integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140]36992-4.041-0.0286No
146ADRB2adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:286]37005-4.1140.0023No
Table: GSEA details [plain text format]



Fig 2: BMI1_DN.V1_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BMI1_DN.V1_UP: Random ES distribution   
Gene set null distribution of ES for BMI1_DN.V1_UP