Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CAHOY_OLIGODENDROCUTIC |
| Enrichment Score (ES) | -0.6711343 |
| Normalized Enrichment Score (NES) | -1.4283414 |
| Nominal p-value | 0.0035005833 |
| FDR q-value | 0.054134045 |
| FWER p-Value | 0.378 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 469 | 2.242 | 0.0136 | No |
| 2 | DOCK10 | dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479] | 633 | 1.961 | 0.0321 | No |
| 3 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 923 | 1.595 | 0.0430 | No |
| 4 | USP16 | ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614] | 1298 | 1.305 | 0.0482 | No |
| 5 | ADGRL2 | adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582] | 2206 | 0.876 | 0.0339 | No |
| 6 | HIP1R | huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415] | 2400 | 0.809 | 0.0382 | No |
| 7 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 2609 | 0.745 | 0.0413 | No |
| 8 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 3396 | 0.544 | 0.0264 | No |
| 9 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 3563 | 0.504 | 0.0278 | No |
| 10 | BCAS1 | brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974] | 3614 | 0.493 | 0.0323 | No |
| 11 | SRPK3 | SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402] | 3969 | 0.428 | 0.0277 | No |
| 12 | POP4 | POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081] | 4077 | 0.409 | 0.0296 | No |
| 13 | PUS7 | pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033] | 4863 | 0.266 | 0.0115 | No |
| 14 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 5553 | 0.148 | -0.0054 | No |
| 15 | NGRN | neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077] | 6007 | 0.085 | -0.0166 | No |
| 16 | BCR | BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014] | 6105 | 0.070 | -0.0184 | No |
| 17 | CSDC2 | cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359] | 6496 | 0.006 | -0.0289 | No |
| 18 | NCMAP | non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332] | 7100 | 0.000 | -0.0452 | No |
| 19 | GAL3ST1 | galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240] | 7239 | 0.000 | -0.0489 | No |
| 20 | CNTNAP2 | contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830] | 7592 | 0.000 | -0.0585 | No |
| 21 | FA2H | fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] | 7843 | 0.000 | -0.0652 | No |
| 22 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8450 | 0.000 | -0.0816 | No |
| 23 | MAP6D1 | MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753] | 8637 | 0.000 | -0.0866 | No |
| 24 | SOX10 | SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190] | 9012 | 0.000 | -0.0967 | No |
| 25 | NINJ2 | ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825] | 10050 | 0.000 | -0.1248 | No |
| 26 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 10247 | 0.000 | -0.1301 | No |
| 27 | TSPAN2 | tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659] | 11695 | 0.000 | -0.1692 | No |
| 28 | ATP10B | ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543] | 12334 | 0.000 | -0.1864 | No |
| 29 | TENM1 | teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117] | 12890 | 0.000 | -0.2014 | No |
| 30 | CDR2L | cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] | 13212 | 0.000 | -0.2101 | No |
| 31 | DMRTA1 | DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826] | 15057 | 0.000 | -0.2600 | No |
| 32 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16118 | 0.000 | -0.2886 | No |
| 33 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16444 | 0.000 | -0.2974 | No |
| 34 | GPR17 | G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471] | 17528 | 0.000 | -0.3267 | No |
| 35 | SEMA3D | semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] | 17909 | 0.000 | -0.3370 | No |
| 36 | BFSP2 | beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041] | 18249 | 0.000 | -0.3461 | No |
| 37 | FEZF2 | FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506] | 18681 | 0.000 | -0.3578 | No |
| 38 | AGAP11 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [Source:HGNC Symbol;Acc:HGNC:29421] | 19688 | 0.000 | -0.3850 | No |
| 39 | DUSP15 | dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236] | 20641 | 0.000 | -0.4107 | No |
| 40 | GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] | 20748 | 0.000 | -0.4136 | No |
| 41 | GJE1 | gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251] | 21019 | 0.000 | -0.4209 | No |
| 42 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21445 | 0.000 | -0.4324 | No |
| 43 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 21940 | 0.000 | -0.4457 | No |
| 44 | FAM89A | family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057] | 22743 | 0.000 | -0.4674 | No |
| 45 | LHFPL6 | LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586] | 22804 | 0.000 | -0.4690 | No |
| 46 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 23078 | 0.000 | -0.4764 | No |
| 47 | RBM11 | RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897] | 23813 | 0.000 | -0.4962 | No |
| 48 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24607 | 0.000 | -0.5177 | No |
| 49 | UGT8 | UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555] | 25064 | 0.000 | -0.5300 | No |
| 50 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 26292 | 0.000 | -0.5632 | No |
| 51 | SOX8 | SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203] | 26362 | 0.000 | -0.5650 | No |
| 52 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 27736 | -0.002 | -0.6021 | No |
| 53 | PRKCQ | protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] | 28266 | -0.092 | -0.6154 | No |
| 54 | SPEG | striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901] | 28683 | -0.147 | -0.6249 | No |
| 55 | KCTD1 | potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249] | 29287 | -0.226 | -0.6385 | No |
| 56 | TLCD3A | TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646] | 29537 | -0.255 | -0.6423 | No |
| 57 | BACE1 | beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933] | 29793 | -0.294 | -0.6457 | No |
| 58 | PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581] | 29844 | -0.300 | -0.6436 | No |
| 59 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 30724 | -0.436 | -0.6622 | No |
| 60 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 30812 | -0.451 | -0.6593 | No |
| 61 | EPN2 | epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639] | 30994 | -0.478 | -0.6586 | No |
| 62 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 31459 | -0.562 | -0.6646 | Yes |
| 63 | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 31659 | -0.597 | -0.6629 | Yes |
| 64 | WIPF1 | WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736] | 31809 | -0.628 | -0.6596 | Yes |
| 65 | GNG8 | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] | 32028 | -0.676 | -0.6576 | Yes |
| 66 | CPOX | coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321] | 32260 | -0.707 | -0.6556 | Yes |
| 67 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 32389 | -0.744 | -0.6503 | Yes |
| 68 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 32448 | -0.760 | -0.6430 | Yes |
| 69 | FBXO7 | F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586] | 32563 | -0.787 | -0.6368 | Yes |
| 70 | DUSP19 | dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894] | 32781 | -0.844 | -0.6328 | Yes |
| 71 | COL20A1 | collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670] | 32829 | -0.855 | -0.6241 | Yes |
| 72 | RTKN | rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] | 32927 | -0.884 | -0.6163 | Yes |
| 73 | RNASEH2B | ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671] | 33070 | -0.919 | -0.6094 | Yes |
| 74 | RNF122 | ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147] | 33172 | -0.946 | -0.6011 | Yes |
| 75 | DCPS | decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812] | 33450 | -1.017 | -0.5966 | Yes |
| 76 | PPP1R21 | protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595] | 33619 | -1.063 | -0.5887 | Yes |
| 77 | SERINC5 | serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825] | 33627 | -1.066 | -0.5764 | Yes |
| 78 | DOCK7 | dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190] | 33764 | -1.110 | -0.5671 | Yes |
| 79 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 34019 | -1.196 | -0.5600 | Yes |
| 80 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 34056 | -1.208 | -0.5468 | Yes |
| 81 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 34134 | -1.233 | -0.5344 | Yes |
| 82 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 34296 | -1.291 | -0.5237 | Yes |
| 83 | RCBTB1 | RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243] | 34667 | -1.462 | -0.5165 | Yes |
| 84 | AP5Z1 | adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197] | 35270 | -1.768 | -0.5121 | Yes |
| 85 | CLYBL | citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355] | 35514 | -1.921 | -0.4962 | Yes |
| 86 | PKIG | cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019] | 35777 | -2.111 | -0.4785 | Yes |
| 87 | KIAA1958 | KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427] | 35807 | -2.131 | -0.4544 | Yes |
| 88 | ABHD8 | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] | 36060 | -2.345 | -0.4337 | Yes |
| 89 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36070 | -2.353 | -0.4064 | Yes |
| 90 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36352 | -2.643 | -0.3830 | Yes |
| 91 | IFFO1 | intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970] | 36443 | -2.761 | -0.3531 | Yes |
| 92 | MAP3K15 | mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689] | 36554 | -2.911 | -0.3220 | Yes |
| 93 | PLXNB3 | plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105] | 36636 | -3.058 | -0.2884 | Yes |
| 94 | LCORL | ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776] | 36712 | -3.203 | -0.2529 | Yes |
| 95 | CILK1 | ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219] | 36757 | -3.317 | -0.2152 | Yes |
| 96 | PRKAG2 | protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386] | 36777 | -3.356 | -0.1764 | Yes |
| 97 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 36838 | -3.500 | -0.1371 | Yes |
| 98 | LRRC75A | leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403] | 36985 | -3.992 | -0.0943 | Yes |
| 99 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36995 | -4.056 | -0.0470 | Yes |
| 100 | P4HA2 | prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547] | 37023 | -4.230 | 0.0018 | Yes |
