Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.67394984 |
| Normalized Enrichment Score (NES) | -1.4578819 |
| Nominal p-value | 0.002259887 |
| FDR q-value | 0.03993665 |
| FWER p-Value | 0.216 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 524 | 2.135 | 0.0041 | No |
| 2 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 567 | 2.054 | 0.0205 | No |
| 3 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 748 | 1.798 | 0.0310 | No |
| 4 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 851 | 1.689 | 0.0427 | No |
| 5 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 1276 | 1.320 | 0.0425 | No |
| 6 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 1431 | 1.226 | 0.0488 | No |
| 7 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 2637 | 0.737 | 0.0225 | No |
| 8 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 2703 | 0.721 | 0.0269 | No |
| 9 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 3070 | 0.623 | 0.0223 | No |
| 10 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 3413 | 0.540 | 0.0177 | No |
| 11 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 3726 | 0.473 | 0.0133 | No |
| 12 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 3878 | 0.443 | 0.0130 | No |
| 13 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 3966 | 0.429 | 0.0143 | No |
| 14 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 4401 | 0.348 | 0.0056 | No |
| 15 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 4639 | 0.303 | 0.0017 | No |
| 16 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 4686 | 0.297 | 0.0030 | No |
| 17 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 4976 | 0.244 | -0.0027 | No |
| 18 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 4995 | 0.241 | -0.0011 | No |
| 19 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 5115 | 0.223 | -0.0024 | No |
| 20 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 5241 | 0.205 | -0.0041 | No |
| 21 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 6393 | 0.021 | -0.0350 | No |
| 22 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 6881 | 0.000 | -0.0482 | No |
| 23 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 7149 | 0.000 | -0.0554 | No |
| 24 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7996 | 0.000 | -0.0783 | No |
| 25 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 8130 | 0.000 | -0.0819 | No |
| 26 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9309 | 0.000 | -0.1138 | No |
| 27 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 9687 | 0.000 | -0.1240 | No |
| 28 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11414 | 0.000 | -0.1707 | No |
| 29 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13028 | 0.000 | -0.2143 | No |
| 30 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13333 | 0.000 | -0.2225 | No |
| 31 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13498 | 0.000 | -0.2270 | No |
| 32 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13554 | 0.000 | -0.2285 | No |
| 33 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 14086 | 0.000 | -0.2428 | No |
| 34 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14428 | 0.000 | -0.2521 | No |
| 35 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15970 | 0.000 | -0.2937 | No |
| 36 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16351 | 0.000 | -0.3040 | No |
| 37 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 17608 | 0.000 | -0.3380 | No |
| 38 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17948 | 0.000 | -0.3472 | No |
| 39 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17967 | 0.000 | -0.3477 | No |
| 40 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18483 | 0.000 | -0.3616 | No |
| 41 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21896 | 0.000 | -0.4539 | No |
| 42 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 22595 | 0.000 | -0.4728 | No |
| 43 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22601 | 0.000 | -0.4729 | No |
| 44 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22646 | 0.000 | -0.4741 | No |
| 45 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22846 | 0.000 | -0.4795 | No |
| 46 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23851 | 0.000 | -0.5066 | No |
| 47 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 26058 | 0.000 | -0.5663 | No |
| 48 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 26256 | 0.000 | -0.5717 | No |
| 49 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 26306 | 0.000 | -0.5730 | No |
| 50 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27483 | 0.000 | -0.6048 | No |
| 51 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 27794 | -0.014 | -0.6131 | No |
| 52 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 27836 | -0.023 | -0.6140 | No |
| 53 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 28108 | -0.070 | -0.6207 | No |
| 54 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 28294 | -0.095 | -0.6249 | No |
| 55 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 28335 | -0.101 | -0.6251 | No |
| 56 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 28347 | -0.102 | -0.6245 | No |
| 57 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 28527 | -0.128 | -0.6283 | No |
| 58 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 28638 | -0.141 | -0.6301 | No |
| 59 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 28839 | -0.171 | -0.6340 | No |
| 60 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 28969 | -0.180 | -0.6360 | No |
| 61 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 28979 | -0.182 | -0.6346 | No |
| 62 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 29101 | -0.198 | -0.6362 | No |
| 63 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 29121 | -0.201 | -0.6350 | No |
| 64 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 29351 | -0.231 | -0.6392 | No |
| 65 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 29600 | -0.264 | -0.6437 | No |
| 66 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 29776 | -0.291 | -0.6459 | No |
| 67 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 30509 | -0.402 | -0.6623 | No |
| 68 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 30872 | -0.462 | -0.6681 | No |
| 69 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 30962 | -0.474 | -0.6665 | No |
| 70 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 30967 | -0.474 | -0.6626 | No |
| 71 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 31239 | -0.518 | -0.6655 | No |
| 72 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 31392 | -0.548 | -0.6649 | No |
| 73 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 31728 | -0.613 | -0.6687 | Yes |
| 74 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 31794 | -0.625 | -0.6651 | Yes |
| 75 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 31914 | -0.651 | -0.6628 | Yes |
| 76 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 32039 | -0.677 | -0.6603 | Yes |
| 77 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 32292 | -0.717 | -0.6610 | Yes |
| 78 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 32388 | -0.744 | -0.6572 | Yes |
| 79 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 32426 | -0.752 | -0.6518 | Yes |
| 80 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 32600 | -0.797 | -0.6497 | Yes |
| 81 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 32813 | -0.851 | -0.6481 | Yes |
| 82 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 33022 | -0.906 | -0.6460 | Yes |
| 83 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 33032 | -0.909 | -0.6385 | Yes |
| 84 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 33077 | -0.920 | -0.6318 | Yes |
| 85 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 33170 | -0.946 | -0.6262 | Yes |
| 86 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 33626 | -1.066 | -0.6294 | Yes |
| 87 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 33642 | -1.074 | -0.6207 | Yes |
| 88 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 33697 | -1.091 | -0.6128 | Yes |
| 89 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 33770 | -1.111 | -0.6052 | Yes |
| 90 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 34069 | -1.213 | -0.6029 | Yes |
| 91 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34383 | -1.330 | -0.6000 | Yes |
| 92 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 34505 | -1.382 | -0.5915 | Yes |
| 93 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 34781 | -1.516 | -0.5860 | Yes |
| 94 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 34791 | -1.519 | -0.5732 | Yes |
| 95 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 34800 | -1.524 | -0.5604 | Yes |
| 96 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 34809 | -1.529 | -0.5476 | Yes |
| 97 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 35016 | -1.623 | -0.5393 | Yes |
| 98 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 35047 | -1.643 | -0.5260 | Yes |
| 99 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 35074 | -1.655 | -0.5126 | Yes |
| 100 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 35095 | -1.664 | -0.4989 | Yes |
| 101 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 35114 | -1.675 | -0.4851 | Yes |
| 102 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 35292 | -1.785 | -0.4746 | Yes |
| 103 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 35318 | -1.803 | -0.4599 | Yes |
| 104 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 35326 | -1.808 | -0.4446 | Yes |
| 105 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 35438 | -1.880 | -0.4315 | Yes |
| 106 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 35703 | -2.058 | -0.4211 | Yes |
| 107 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 35768 | -2.103 | -0.4048 | Yes |
| 108 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 35885 | -2.206 | -0.3891 | Yes |
| 109 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 35903 | -2.221 | -0.3706 | Yes |
| 110 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35977 | -2.277 | -0.3531 | Yes |
| 111 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35989 | -2.284 | -0.3339 | Yes |
| 112 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 36117 | -2.400 | -0.3168 | Yes |
| 113 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36210 | -2.489 | -0.2980 | Yes |
| 114 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 36227 | -2.509 | -0.2770 | Yes |
| 115 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 36247 | -2.534 | -0.2558 | Yes |
| 116 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 36345 | -2.638 | -0.2359 | Yes |
| 117 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36408 | -2.708 | -0.2144 | Yes |
| 118 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 36418 | -2.725 | -0.1914 | Yes |
| 119 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 36505 | -2.851 | -0.1693 | Yes |
| 120 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 36527 | -2.877 | -0.1453 | Yes |
| 121 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 36539 | -2.892 | -0.1209 | Yes |
| 122 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 36566 | -2.936 | -0.0965 | Yes |
| 123 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 36626 | -3.036 | -0.0721 | Yes |
| 124 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 36689 | -3.156 | -0.0468 | Yes |
| 125 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36752 | -3.297 | -0.0203 | Yes |
| 126 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 36820 | -3.445 | 0.0073 | Yes |
