Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetESC_J1_UP_EARLY.V1_DN
Enrichment Score (ES)0.48669532
Normalized Enrichment Score (NES)1.3221447
Nominal p-value0.022727273
FDR q-value0.09834116
FWER p-Value0.346
Table: GSEA Results Summary



Fig 1: Enrichment plot: ESC_J1_UP_EARLY.V1_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ID1inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360]164.7650.0268Yes
2SOCS3suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391]204.6690.0534Yes
3ZFP36ZFP36 ring finger protein [Source:HGNC Symbol;Acc:HGNC:12862]314.4030.0783Yes
4CEBPDCCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835]324.4010.1035Yes
5EDN1endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176]474.2370.1274Yes
6ID3inhibitor of DNA binding 3, HLH protein [Source:HGNC Symbol;Acc:HGNC:5362]504.1890.1513Yes
7BCL3BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998]524.1830.1752Yes
8MYCMYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]963.7120.1952Yes
9TMEM98transmembrane protein 98 [Source:HGNC Symbol;Acc:HGNC:24529]1083.6380.2157Yes
10JUNBJunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205]1283.4950.2352Yes
11ACTA1actin alpha 1, skeletal muscle [Source:HGNC Symbol;Acc:HGNC:129]2023.0950.2509Yes
12SERPINE1serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583]2472.8700.2662Yes
13STAT3signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364]3462.5340.2780Yes
14RIOK2RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999]4542.2770.2881Yes
15GPATCH4G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]5902.0250.2960Yes
16NAB2NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627]6002.0130.3073Yes
17RRP12ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100]6531.9330.3170Yes
18ATF5activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790]7951.7420.3231Yes
19MDN1midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302]8661.6640.3307Yes
20ZBTB21zinc finger and BTB domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13083]8731.6550.3400Yes
21ANXA1annexin A1 [Source:HGNC Symbol;Acc:HGNC:533]9181.6000.3480Yes
22UBA7ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471]9401.5810.3565Yes
23TNFRSF12ATNF receptor superfamily member 12A [Source:HGNC Symbol;Acc:HGNC:18152]9891.5410.3640Yes
24APOBRapolipoprotein B receptor [Source:HGNC Symbol;Acc:HGNC:24087]10061.5250.3723Yes
25BMS1BMS1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:23505]13041.3000.3716Yes
26PAFAH2platelet activating factor acetylhydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8579]13801.2540.3768Yes
27EGR1early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238]13961.2440.3835Yes
28TREX1three prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:12269]13981.2420.3906Yes
29TLE4TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840]14201.2310.3970Yes
30KTI12KTI12 chromatin associated homolog [Source:HGNC Symbol;Acc:HGNC:25160]14601.2050.4029Yes
31EEF1AKNMTeEF1A lysine and N-terminal methyltransferase [Source:HGNC Symbol;Acc:HGNC:24248]15011.1780.4085Yes
32WSB1WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221]15051.1760.4152Yes
33BMP1bone morphogenetic protein 1 [Source:HGNC Symbol;Acc:HGNC:1067]15221.1660.4214Yes
34LIMS2LIM zinc finger domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16084]15351.1620.4277Yes
35PPCSphosphopantothenoylcysteine synthetase [Source:HGNC Symbol;Acc:HGNC:25686]15431.1550.4341Yes
36RRP8ribosomal RNA processing 8 [Source:HGNC Symbol;Acc:HGNC:29030]15571.1510.4404Yes
37ARHGEF10LRho guanine nucleotide exchange factor 10 like [Source:HGNC Symbol;Acc:HGNC:25540]17021.0790.4426Yes
38LLPHLLP homolog, long-term synaptic facilitation factor [Source:HGNC Symbol;Acc:HGNC:28229]17391.0580.4477Yes
39LPPLIM domain containing preferred translocation partner in lipoma [Source:HGNC Symbol;Acc:HGNC:6679]18281.0230.4512Yes
40TRPS1transcriptional repressor GATA binding 1 [Source:HGNC Symbol;Acc:HGNC:12340]18601.0110.4561Yes
41FBXO33F-box protein 33 [Source:HGNC Symbol;Acc:HGNC:19833]19110.9920.4604Yes
42MTG2mitochondrial ribosome associated GTPase 2 [Source:HGNC Symbol;Acc:HGNC:16239]20890.9160.4609Yes
43HYAL2hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:5321]21100.9070.4655Yes
44DBR1debranching RNA lariats 1 [Source:HGNC Symbol;Acc:HGNC:15594]22030.8770.4681Yes
45TGM1transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777]24060.8080.4672Yes
46ANXA5annexin A5 [Source:HGNC Symbol;Acc:HGNC:543]24340.7980.4710Yes
47GBP2guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183]25200.7730.4732Yes
48GBP1guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182]25420.7670.4770Yes
49MYL9myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754]27950.7000.4742Yes
50NSUN4NOP2/Sun RNA methyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:31802]28320.6890.4771Yes
51GSPT2G1 to S phase transition 2 [Source:HGNC Symbol;Acc:HGNC:4622]29470.6560.4778Yes
52PHBprohibitin [Source:HGNC Symbol;Acc:HGNC:8912]32540.5740.4728Yes
53PACRGLparkin coregulated like [Source:HGNC Symbol;Acc:HGNC:28442]33260.5590.4741Yes
54USP38ubiquitin specific peptidase 38 [Source:HGNC Symbol;Acc:HGNC:20067]33750.5490.4759Yes
55MED6mediator complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:19970]34110.5400.4780Yes
56PTGISprostaglandin I2 synthase [Source:HGNC Symbol;Acc:HGNC:9603]35190.5150.4781Yes
57UHRF1BP1LUHRF1 binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:29102]35240.5140.4809Yes
58ATP9BATPase phospholipid transporting 9B (putative) [Source:HGNC Symbol;Acc:HGNC:13541]35340.5110.4836Yes
59LTBlymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]35610.5050.4858Yes
60SAP30BPSAP30 binding protein [Source:HGNC Symbol;Acc:HGNC:30785]37210.4740.4842Yes
61SLC30A1solute carrier family 30 member 1 [Source:HGNC Symbol;Acc:HGNC:11012]37380.4710.4864Yes
62UXTubiquitously expressed prefoldin like chaperone [Source:HGNC Symbol;Acc:HGNC:12641]38250.4530.4867Yes
63CCDC59coiled-coil domain containing 59 [Source:HGNC Symbol;Acc:HGNC:25005]39290.4340.4864No
64NIFKnucleolar protein interacting with the FHA domain of MKI67 [Source:HGNC Symbol;Acc:HGNC:17838]41760.3910.4820No
65TRIB3tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228]43130.3650.4804No
66BAG5BAG cochaperone 5 [Source:HGNC Symbol;Acc:HGNC:941]43650.3560.4810No
67FGF17fibroblast growth factor 17 [Source:HGNC Symbol;Acc:HGNC:3673]43930.3480.4823No
68SPCS3signal peptidase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26212]45760.3180.4792No
69FAM118Bfamily with sequence similarity 118 member B [Source:HGNC Symbol;Acc:HGNC:26110]51190.2220.4658No
70DIMT1DIMT1 rRNA methyltransferase and ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:30217]52880.1970.4623No
71NOL12nucleolar protein 12 [Source:HGNC Symbol;Acc:HGNC:28585]53120.1930.4628No
72DNAJC24DnaJ heat shock protein family (Hsp40) member C24 [Source:HGNC Symbol;Acc:HGNC:26979]54240.1740.4608No
73RPS6KB2ribosomal protein S6 kinase B2 [Source:HGNC Symbol;Acc:HGNC:10437]54870.1600.4600No
74BRWD1bromodomain and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:12760]57000.1250.4550No
75SPRY4sprouty RTK signaling antagonist 4 [Source:HGNC Symbol;Acc:HGNC:15533]57420.1180.4546No
76NUDT11nudix hydrolase 11 [Source:HGNC Symbol;Acc:HGNC:18011]58400.1040.4525No
77BLOC1S4biogenesis of lysosomal organelles complex 1 subunit 4 [Source:HGNC Symbol;Acc:HGNC:24206]59120.1010.4512No
78C11orf24chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]59840.0880.4498No
79SLC66A1solute carrier family 66 member 1 [Source:HGNC Symbol;Acc:HGNC:26001]61400.0650.4459No
80LAMC2laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493]64490.0070.4376No
81ZNF35zinc finger protein 35 [Source:HGNC Symbol;Acc:HGNC:13099]68530.0000.4267No
82FGF18fibroblast growth factor 18 [Source:HGNC Symbol;Acc:HGNC:3674]71210.0000.4195No
83TPD52L3TPD52 like 3 [Source:HGNC Symbol;Acc:HGNC:23382]88190.0000.3735No
84C16orf74chromosome 16 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:23362]94890.0000.3554No
85ADAM23ADAM metallopeptidase domain 23 [Source:HGNC Symbol;Acc:HGNC:202]99130.0000.3439No
86NINJ2ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825]100500.0000.3403No
87CTRB1chymotrypsinogen B1 [Source:HGNC Symbol;Acc:HGNC:2521]111410.0000.3107No
88ERASES cell expressed Ras [Source:HGNC Symbol;Acc:HGNC:5174]116530.0000.2969No
89IGFBP3insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]119500.0000.2889No
90CNN1calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]124460.0000.2755No
91TGM3transglutaminase 3 [Source:HGNC Symbol;Acc:HGNC:11779]126660.0000.2695No
92GAP43growth associated protein 43 [Source:HGNC Symbol;Acc:HGNC:4140]129590.0000.2616No
93GBX2gastrulation brain homeobox 2 [Source:HGNC Symbol;Acc:HGNC:4186]130780.0000.2584No
94ZFP57ZFP57 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:18791]134180.0000.2493No
95TMEM121transmembrane protein 121 [Source:HGNC Symbol;Acc:HGNC:20511]136110.0000.2441No
96SYT12synaptotagmin 12 [Source:HGNC Symbol;Acc:HGNC:18381]138380.0000.2379No
97TAGLNtransgelin [Source:HGNC Symbol;Acc:HGNC:11553]139390.0000.2352No
98TLR9toll like receptor 9 [Source:HGNC Symbol;Acc:HGNC:15633]143780.0000.2234No
99SLC35G3solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848]160260.0000.1787No
100FETUBfetuin B [Source:HGNC Symbol;Acc:HGNC:3658]170390.0000.1513No
101RPP25ribonuclease P and MRP subunit p25 [Source:HGNC Symbol;Acc:HGNC:30361]170410.0000.1513No
102VAX2ventral anterior homeobox 2 [Source:HGNC Symbol;Acc:HGNC:12661]173810.0000.1421No
103PPP1R1Aprotein phosphatase 1 regulatory inhibitor subunit 1A [Source:HGNC Symbol;Acc:HGNC:9286]176910.0000.1338No
104DRD4dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025]185220.0000.1113No
105BMP4bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071]191050.0000.0955No
106RAMP1receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843]203680.0000.0613No
107INHBBinhibin subunit beta B [Source:HGNC Symbol;Acc:HGNC:6067]203820.0000.0610No
108TCF15transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11627]205370.0000.0568No
109KLF1Kruppel like factor 1 [Source:HGNC Symbol;Acc:HGNC:6345]206760.0000.0531No
110C19orf48chromosome 19 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29667]220210.0000.0167No
111CCN1cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654]230790.000-0.0120No
112FOXD3forkhead box D3 [Source:HGNC Symbol;Acc:HGNC:3804]238340.000-0.0324No
113LAMA1laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481]239190.000-0.0347No
114LALBAlactalbumin alpha [Source:HGNC Symbol;Acc:HGNC:6480]241600.000-0.0412No
115ZBP1Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176]261470.000-0.0950No
116MAPTmicrotubule associated protein tau [Source:HGNC Symbol;Acc:HGNC:6893]276600.000-0.1359No
117PPP2R3Aprotein phosphatase 2 regulatory subunit B''alpha [Source:HGNC Symbol;Acc:HGNC:9307]27952-0.044-0.1436No
118DUSP6dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]28292-0.094-0.1522No
119SLC16A2solute carrier family 16 member 2 [Source:HGNC Symbol;Acc:HGNC:10923]28452-0.117-0.1558No
120RELBRELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956]28505-0.125-0.1565No
121UBE2J1ubiquitin conjugating enzyme E2 J1 [Source:HGNC Symbol;Acc:HGNC:17598]28507-0.125-0.1558No
122REM2RRAD and GEM like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:20248]28559-0.133-0.1565No
123DPYSL5dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637]28615-0.139-0.1572No
124LUC7L3LUC7 like 3 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:24309]28727-0.153-0.1593No
125QSER1glutamine and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:26154]28753-0.157-0.1591No
126EMP2epithelial membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:3334]28945-0.179-0.1632No
127EPOPelongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493]28956-0.179-0.1625No
128ANXA3annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]29116-0.200-0.1656No
129AMHanti-Mullerian hormone [Source:HGNC Symbol;Acc:HGNC:464]29251-0.220-0.1680No
130ENTPD4ectonucleoside triphosphate diphosphohydrolase 4 [Source:HGNC Symbol;Acc:HGNC:14573]29277-0.224-0.1674No
131GID8GID complex subunit 8 homolog [Source:HGNC Symbol;Acc:HGNC:15857]29285-0.226-0.1663No
132MRPS11mitochondrial ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:14050]29440-0.241-0.1691No
133STK4serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]29623-0.269-0.1725No
134MAPK7mitogen-activated protein kinase 7 [Source:HGNC Symbol;Acc:HGNC:6880]29885-0.307-0.1778No
135VPS33BVPS33B late endosome and lysosome associated [Source:HGNC Symbol;Acc:HGNC:12712]29914-0.310-0.1768No
136GNA14G protein subunit alpha 14 [Source:HGNC Symbol;Acc:HGNC:4382]30039-0.330-0.1783No
137B3GALT6beta-1,3-galactosyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:17978]30136-0.347-0.1789No
138RAB33ARAB33A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9773]30146-0.349-0.1771No
139DNAJC30DnaJ heat shock protein family (Hsp40) member C30 [Source:HGNC Symbol;Acc:HGNC:16410]30392-0.388-0.1815No
140ARHGAP35Rho GTPase activating protein 35 [Source:HGNC Symbol;Acc:HGNC:4591]30754-0.441-0.1888No
141MRASmuscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227]31090-0.492-0.1951No
142ADAP2ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487]31154-0.504-0.1939No
143FKBPLFKBP prolyl isomerase like [Source:HGNC Symbol;Acc:HGNC:13949]31717-0.610-0.2056No
144CENPBcentromere protein B [Source:HGNC Symbol;Acc:HGNC:1852]31721-0.611-0.2022No
145MVKmevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530]31858-0.638-0.2022No
146DCLRE1BDNA cross-link repair 1B [Source:HGNC Symbol;Acc:HGNC:17641]32253-0.707-0.2089No
147PTPN22protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652]32686-0.819-0.2159No
148ETV4ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493]33660-1.079-0.2361No
149TMC6transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]33984-1.182-0.2380No
150ANGPTL4angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]34518-1.388-0.2445No
151KLF13Kruppel like factor 13 [Source:HGNC Symbol;Acc:HGNC:13672]34768-1.509-0.2427No
152SFNstratifin [Source:HGNC Symbol;Acc:HGNC:10773]34839-1.544-0.2357No
153DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides 1 [Source:HGNC Symbol;Acc:HGNC:16500]35044-1.640-0.2319No
154ERFETS2 repressor factor [Source:HGNC Symbol;Acc:HGNC:3444]35054-1.646-0.2227No
155TRAIPTRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764]35105-1.670-0.2145No
156REEP6receptor accessory protein 6 [Source:HGNC Symbol;Acc:HGNC:30078]35261-1.764-0.2086No
157CIRBPcold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]35438-1.880-0.2026No
158NAPSAnapsin A aspartic peptidase [Source:HGNC Symbol;Acc:HGNC:13395]35507-1.916-0.1935No
159MAD1L1mitotic arrest deficient 1 like 1 [Source:HGNC Symbol;Acc:HGNC:6762]35596-1.983-0.1846No
160TSPYL4TSPY like 4 [Source:HGNC Symbol;Acc:HGNC:21559]35678-2.039-0.1751No
161CRYL1crystallin lambda 1 [Source:HGNC Symbol;Acc:HGNC:18246]35681-2.041-0.1635No
162HASPINhistone H3 associated protein kinase [Source:HGNC Symbol;Acc:HGNC:19682]35801-2.128-0.1545No
163RECQLRecQ like helicase [Source:HGNC Symbol;Acc:HGNC:9948]35931-2.244-0.1452No
164H2BC4H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757]36027-2.318-0.1345No
165KLF4Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348]36031-2.319-0.1213No
166VWA5Avon Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]36059-2.345-0.1086No
167RNASELribonuclease L [Source:HGNC Symbol;Acc:HGNC:10050]36205-2.483-0.0984No
168ZFP36L1ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]36236-2.523-0.0848No
169AP4M1adaptor related protein complex 4 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:574]36598-2.987-0.0775No
170TREM2triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761]36805-3.406-0.0636No
171CORO2Acoronin 2A [Source:HGNC Symbol;Acc:HGNC:2255]36898-3.644-0.0452No
172TFEBtranscription factor EB [Source:HGNC Symbol;Acc:HGNC:11753]36990-4.024-0.0247No
173RNASE4ribonuclease A family member 4 [Source:HGNC Symbol;Acc:HGNC:10047]37078-4.7810.0003No
Table: GSEA details [plain text format]



Fig 2: ESC_J1_UP_EARLY.V1_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ESC_J1_UP_EARLY.V1_DN: Random ES distribution   
Gene set null distribution of ES for ESC_J1_UP_EARLY.V1_DN