Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetKRAS.300_UP.V1_UP
Enrichment Score (ES)0.47097287
Normalized Enrichment Score (NES)1.2654339
Nominal p-value0.01
FDR q-value0.12234677
FWER p-Value0.508
Table: GSEA Results Summary



Fig 1: Enrichment plot: KRAS.300_UP.V1_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CSF3colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438]114.8220.0659Yes
2IL1RL1interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998]454.2490.1234Yes
3GLRXglutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330]923.7360.1735Yes
4SPP1secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255]1173.5710.2219Yes
5IL13RA2interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975]2212.9900.2602Yes
6GLDCglycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313]2622.8290.2980Yes
7DHRS9dehydrogenase/reductase 9 [Source:HGNC Symbol;Acc:HGNC:16888]2802.7430.3352Yes
8DCBLD2discoidin, CUB and LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24627]2892.7260.3724Yes
9DOCK4dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192]4352.3180.4004Yes
10ADAM8ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215]10501.4860.4042Yes
11ITGB2integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]10951.4550.4230Yes
12DDX6DEAD-box helicase 6 [Source:HGNC Symbol;Acc:HGNC:2747]14951.1810.4284Yes
13GPR4G protein-coupled receptor 4 [Source:HGNC Symbol;Acc:HGNC:4497]15801.1370.4417Yes
14ETV1ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490]15901.1330.4571Yes
15SPRY2sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270]16411.1110.4710Yes
16ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080]24560.7920.4598No
17EVI2Aecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499]26090.7450.4659No
18TAPT1transmembrane anterior posterior transformation 1 [Source:HGNC Symbol;Acc:HGNC:26887]35310.5110.4480No
19RREB1ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]38350.4510.4460No
20CXCL3C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604]40870.4070.4448No
21NME5NME/NM23 family member 5 [Source:HGNC Symbol;Acc:HGNC:7853]41270.3990.4493No
22A2Malpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]41950.3890.4528No
23CFAP69cilia and flagella associated protein 69 [Source:HGNC Symbol;Acc:HGNC:26107]49420.2510.4360No
24RDH5retinol dehydrogenase 5 [Source:HGNC Symbol;Acc:HGNC:9940]49470.2500.4394No
25LRCH1leucine rich repeats and calponin homology domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20309]53800.1810.4302No
26KCNK10potassium two pore domain channel subfamily K member 10 [Source:HGNC Symbol;Acc:HGNC:6273]55640.1470.4272No
27NAP1L2nucleosome assembly protein 1 like 2 [Source:HGNC Symbol;Acc:HGNC:7638]57800.1110.4229No
28WNT7AWnt family member 7A [Source:HGNC Symbol;Acc:HGNC:12786]60870.0720.4156No
29NAV3neuron navigator 3 [Source:HGNC Symbol;Acc:HGNC:15998]62520.0470.4119No
30SCG5secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816]67520.0000.3984No
31SCG3secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707]67540.0000.3983No
32APODapolipoprotein D [Source:HGNC Symbol;Acc:HGNC:612]70460.0000.3905No
33DYNC1I1dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963]70910.0000.3893No
34DEFB4Adefensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767]73980.0000.3810No
35RNASE1ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044]74540.0000.3795No
36SLCO5A1solute carrier organic anion transporter family member 5A1 [Source:HGNC Symbol;Acc:HGNC:19046]74740.0000.3790No
37ASIC4acid sensing ion channel subunit family member 4 [Source:HGNC Symbol;Acc:HGNC:21263]81340.0000.3611No
38PCDH8protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]83200.0000.3561No
39LINC01140long intergenic non-protein coding RNA 1140 [Source:HGNC Symbol;Acc:HGNC:27922]89020.0000.3404No
40CALB1calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434]89740.0000.3385No
41CRISP1cysteine rich secretory protein 1 [Source:HGNC Symbol;Acc:HGNC:304]93130.0000.3293No
42NPY6Rneuropeptide Y receptor Y6 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:7959]93150.0000.3293No
43CDR1cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798]97200.0000.3184No
44KCNK7potassium two pore domain channel subfamily K member 7 [Source:HGNC Symbol;Acc:HGNC:6282]100040.0000.3107No
45COL26A1collagen type XXVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:18038]100280.0000.3101No
46ADAM19ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]101220.0000.3076No
47GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585]105160.0000.2969No
48RTN1reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467]106790.0000.2926No
49CHGAchromogranin A [Source:HGNC Symbol;Acc:HGNC:1929]107280.0000.2913No
50CHGBchromogranin B [Source:HGNC Symbol;Acc:HGNC:1930]107490.0000.2907No
51PPBPpro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240]111540.0000.2798No
52TFDP3transcription factor Dp family member 3 [Source:HGNC Symbol;Acc:HGNC:24603]113650.0000.2741No
53ERC2ELKS/RAB6-interacting/CAST family member 2 [Source:HGNC Symbol;Acc:HGNC:31922]116390.0000.2667No
54USH1CUSH1 protein network component harmonin [Source:HGNC Symbol;Acc:HGNC:12597]116550.0000.2663No
55PRG3proteoglycan 3, pro eosinophil major basic protein 2 [Source:HGNC Symbol;Acc:HGNC:9363]117020.0000.2651No
56SLC6A15solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621]120090.0000.2568No
57SIGLEC15sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596]120400.0000.2560No
58PTX3pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692]125100.0000.2433No
59APOBEC3Gapolipoprotein B mRNA editing enzyme catalytic subunit 3G [Source:HGNC Symbol;Acc:HGNC:17357]126080.0000.2406No
60ITGBL1integrin subunit beta like 1 [Source:HGNC Symbol;Acc:HGNC:6164]126130.0000.2405No
61GBA3glucosylceramidase beta 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:19069]128510.0000.2341No
62RBP4retinol binding protein 4 [Source:HGNC Symbol;Acc:HGNC:9922]129950.0000.2303No
63OR2B6olfactory receptor family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:8241]136150.0000.2135No
64KIAA1549LKIAA1549 like [Source:HGNC Symbol;Acc:HGNC:24836]138280.0000.2078No
65RELNreelin [Source:HGNC Symbol;Acc:HGNC:9957]139540.0000.2044No
66RETNresistin [Source:HGNC Symbol;Acc:HGNC:20389]140660.0000.2014No
67HSD11B1hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208]145200.0000.1891No
68ZP4zona pellucida glycoprotein 4 [Source:HGNC Symbol;Acc:HGNC:15770]148940.0000.1790No
69TOX3TOX high mobility group box family member 3 [Source:HGNC Symbol;Acc:HGNC:11972]155060.0000.1625No
70PCP4Purkinje cell protein 4 [Source:HGNC Symbol;Acc:HGNC:8742]155540.0000.1612No
71HTR75-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302]156230.0000.1594No
72CELcarboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848]158610.0000.1530No
73CGAglycoprotein hormones, alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:1885]158750.0000.1526No
74MCF2MCF.2 cell line derived transforming sequence [Source:HGNC Symbol;Acc:HGNC:6940]159090.0000.1517No
75G0S2G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229]159100.0000.1517No
76DBHdopamine beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:2689]161000.0000.1466No
77BEX1brain expressed X-linked 1 [Source:HGNC Symbol;Acc:HGNC:1036]166550.0000.1316No
78TRIB2tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809]169110.0000.1247No
79CFHR2complement factor H related 2 [Source:HGNC Symbol;Acc:HGNC:4890]170030.0000.1222No
80SYT1synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509]170690.0000.1205No
81SEMA3Asemaphorin 3A [Source:HGNC Symbol;Acc:HGNC:10723]179100.0000.0978No
82CEACAM3CEA cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:1815]179350.0000.0971No
83MMP1matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155]191330.0000.0647No
84CXCL5C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642]194900.0000.0551No
85GABRA1gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075]199990.0000.0413No
86GABRA3gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077]200030.0000.0412No
87EFCAB6EF-hand calcium binding domain 6 [Source:HGNC Symbol;Acc:HGNC:24204]202330.0000.0350No
88SCN2Asodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588]203380.0000.0322No
89TERTtelomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730]204630.0000.0289No
90MMP11matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157]209280.0000.0163No
91PEG3paternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:8826]215120.0000.0005No
92ZNF528zinc finger protein 528 [Source:HGNC Symbol;Acc:HGNC:29384]219530.000-0.0114No
93NRCAMneuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994]228070.000-0.0345No
94CD1ACD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634]231020.000-0.0424No
95NOL4nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870]234990.000-0.0531No
96SLC25A31solute carrier family 25 member 31 [Source:HGNC Symbol;Acc:HGNC:25319]237860.000-0.0609No
97SNAP25synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132]243430.000-0.0759No
98FAM155Bfamily with sequence similarity 155 member B [Source:HGNC Symbol;Acc:HGNC:30701]246160.000-0.0833No
99SNAP91synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986]248670.000-0.0900No
100LMO3LIM domain only 3 [Source:HGNC Symbol;Acc:HGNC:6643]249420.000-0.0921No
101HAS2hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819]251100.000-0.0966No
102ANK3ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]252240.000-0.0996No
103ANO1anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625]252710.000-0.1009No
104FGF9fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687]256320.000-0.1106No
105SMPXsmall muscle protein X-linked [Source:HGNC Symbol;Acc:HGNC:11122]256990.000-0.1124No
106FNDC8fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286]260720.000-0.1225No
107ITGA2integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137]266570.000-0.1383No
108ASTN1astrotactin 1 [Source:HGNC Symbol;Acc:HGNC:773]267720.000-0.1414No
109CLUL1clusterin like 1 [Source:HGNC Symbol;Acc:HGNC:2096]270730.000-0.1495No
110RCAN2regulator of calcineurin 2 [Source:HGNC Symbol;Acc:HGNC:3041]274800.000-0.1605No
111STC1stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373]276020.000-0.1637No
112ATXN3Lataxin 3 like [Source:HGNC Symbol;Acc:HGNC:24173]27907-0.036-0.1715No
113TFPItissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760]28198-0.085-0.1782No
114DNM3dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]28258-0.090-0.1785No
115DUSP6dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]28292-0.094-0.1781No
116MAP4K1mitogen-activated protein kinase kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6863]28545-0.131-0.1831No
117HPNhepsin [Source:HGNC Symbol;Acc:HGNC:5155]28844-0.172-0.1888No
118KCNH2potassium voltage-gated channel subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:6251]28875-0.175-0.1873No
119RRAGDRas related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]29647-0.271-0.2044No
120DNAJA4DnaJ heat shock protein family (Hsp40) member A4 [Source:HGNC Symbol;Acc:HGNC:14885]29687-0.278-0.2016No
121MAPK10mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:HGNC:6872]29780-0.292-0.2001No
122CEACAM1CEA cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1814]30065-0.335-0.2032No
123MKRN3makorin ring finger protein 3 [Source:HGNC Symbol;Acc:HGNC:7114]30408-0.390-0.2071No
124HEY1hes related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880]30506-0.402-0.2042No
125FABP3fatty acid binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3557]30869-0.462-0.2076No
126SCN1Bsodium voltage-gated channel beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:10586]31206-0.512-0.2097No
127TRIM36tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280]31818-0.629-0.2176No
128CDK5R1cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775]31879-0.644-0.2104No
129KIF5Ckinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325]32031-0.677-0.2052No
130ETV4ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493]33660-1.079-0.2344No
131PDE2Aphosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]33858-1.136-0.2241No
132LILRA6leukocyte immunoglobulin like receptor A6 [Source:HGNC Symbol;Acc:HGNC:15495]33916-1.158-0.2098No
133ANPEPalanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]34032-1.201-0.1964No
134CTNNA2catenin alpha 2 [Source:HGNC Symbol;Acc:HGNC:2510]34493-1.377-0.1899No
135ANGPTL4angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]34518-1.388-0.1715No
136H2BC17H2B clustered histone 17 [Source:HGNC Symbol;Acc:HGNC:4758]34870-1.561-0.1596No
137ETV5ETS variant transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3494]35479-1.899-0.1499No
138ARHGAP24Rho GTPase activating protein 24 [Source:HGNC Symbol;Acc:HGNC:25361]35612-1.997-0.1261No
139GPR19G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473]36179-2.454-0.1077No
140SORL1sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185]36607-3.001-0.0780No
141ATP1A2ATPase Na+/K+ transporting subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:800]36615-3.022-0.0367No
142KIF5Akinesin family member 5A [Source:HGNC Symbol;Acc:HGNC:6323]36876-3.6030.0058No
Table: GSEA details [plain text format]



Fig 2: KRAS.300_UP.V1_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KRAS.300_UP.V1_UP: Random ES distribution   
Gene set null distribution of ES for KRAS.300_UP.V1_UP