Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | KRAS.50_UP.V1_UP |
| Enrichment Score (ES) | 0.70622593 |
| Normalized Enrichment Score (NES) | 1.6115463 |
| Nominal p-value | 0.004201681 |
| FDR q-value | 0.09914047 |
| FWER p-Value | 0.036 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 45 | 4.249 | 0.1371 | Yes |
| 2 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 92 | 3.736 | 0.2574 | Yes |
| 3 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 221 | 2.990 | 0.3512 | Yes |
| 4 | GLDC | glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313] | 262 | 2.829 | 0.4422 | Yes |
| 5 | DHRS9 | dehydrogenase/reductase 9 [Source:HGNC Symbol;Acc:HGNC:16888] | 280 | 2.743 | 0.5310 | Yes |
| 6 | DOCK4 | dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192] | 435 | 2.318 | 0.6023 | Yes |
| 7 | ADAM8 | ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215] | 1050 | 1.486 | 0.6341 | Yes |
| 8 | ITGB2 | integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155] | 1095 | 1.455 | 0.6803 | Yes |
| 9 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 1590 | 1.133 | 0.7038 | Yes |
| 10 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080] | 2456 | 0.792 | 0.7062 | Yes |
| 11 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 3835 | 0.451 | 0.6837 | No |
| 12 | A2M | alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7] | 4195 | 0.389 | 0.6867 | No |
| 13 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6752 | 0.000 | 0.6177 | No |
| 14 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6754 | 0.000 | 0.6176 | No |
| 15 | DYNC1I1 | dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963] | 7091 | 0.000 | 0.6086 | No |
| 16 | PCDH8 | protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660] | 8320 | 0.000 | 0.5754 | No |
| 17 | CALB1 | calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434] | 8974 | 0.000 | 0.5578 | No |
| 18 | CDR1 | cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798] | 9720 | 0.000 | 0.5377 | No |
| 19 | CHGB | chromogranin B [Source:HGNC Symbol;Acc:HGNC:1930] | 10749 | 0.000 | 0.5099 | No |
| 20 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11154 | 0.000 | 0.4990 | No |
| 21 | SIGLEC15 | sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596] | 12040 | 0.000 | 0.4751 | No |
| 22 | RBP4 | retinol binding protein 4 [Source:HGNC Symbol;Acc:HGNC:9922] | 12995 | 0.000 | 0.4494 | No |
| 23 | KIAA1549L | KIAA1549 like [Source:HGNC Symbol;Acc:HGNC:24836] | 13828 | 0.000 | 0.4269 | No |
| 24 | RELN | reelin [Source:HGNC Symbol;Acc:HGNC:9957] | 13954 | 0.000 | 0.4235 | No |
| 25 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14520 | 0.000 | 0.4083 | No |
| 26 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 15623 | 0.000 | 0.3785 | No |
| 27 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15910 | 0.000 | 0.3708 | No |
| 28 | CFHR2 | complement factor H related 2 [Source:HGNC Symbol;Acc:HGNC:4890] | 17003 | 0.000 | 0.3413 | No |
| 29 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19490 | 0.000 | 0.2742 | No |
| 30 | TERT | telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730] | 20463 | 0.000 | 0.2480 | No |
| 31 | MMP11 | matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157] | 20928 | 0.000 | 0.2355 | No |
| 32 | PEG3 | paternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:8826] | 21512 | 0.000 | 0.2197 | No |
| 33 | NRCAM | neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994] | 22807 | 0.000 | 0.1848 | No |
| 34 | CD1A | CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634] | 23102 | 0.000 | 0.1769 | No |
| 35 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 24343 | 0.000 | 0.1434 | No |
| 36 | FAM155B | family with sequence similarity 155 member B [Source:HGNC Symbol;Acc:HGNC:30701] | 24616 | 0.000 | 0.1360 | No |
| 37 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 24867 | 0.000 | 0.1293 | No |
| 38 | LMO3 | LIM domain only 3 [Source:HGNC Symbol;Acc:HGNC:6643] | 24942 | 0.000 | 0.1273 | No |
| 39 | FGF9 | fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] | 25632 | 0.000 | 0.1087 | No |
| 40 | ITGA2 | integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137] | 26657 | 0.000 | 0.0810 | No |
| 41 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 27602 | 0.000 | 0.0556 | No |
| 42 | HPN | hepsin [Source:HGNC Symbol;Acc:HGNC:5155] | 28844 | -0.172 | 0.0277 | No |
| 43 | HEY1 | hes related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880] | 30506 | -0.402 | -0.0041 | No |
| 44 | FABP3 | fatty acid binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3557] | 30869 | -0.462 | 0.0012 | No |
| 45 | KIF5C | kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325] | 32031 | -0.677 | -0.0082 | No |
| 46 | LILRA6 | leukocyte immunoglobulin like receptor A6 [Source:HGNC Symbol;Acc:HGNC:15495] | 33916 | -1.158 | -0.0213 | No |
| 47 | ANGPTL4 | angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039] | 34518 | -1.388 | 0.0076 | No |
| 48 | ETV5 | ETS variant transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3494] | 35479 | -1.899 | 0.0435 | No |
