Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.48104897 |
| Normalized Enrichment Score (NES) | 1.3025115 |
| Nominal p-value | 0.019417476 |
| FDR q-value | 0.1070254 |
| FWER p-Value | 0.398 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 18 | 4.745 | 0.0666 | Yes |
| 2 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 89 | 3.738 | 0.1176 | Yes |
| 3 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 100 | 3.699 | 0.1696 | Yes |
| 4 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 141 | 3.386 | 0.2164 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 223 | 2.980 | 0.2564 | Yes |
| 6 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 288 | 2.726 | 0.2932 | Yes |
| 7 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 357 | 2.508 | 0.3268 | Yes |
| 8 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 382 | 2.458 | 0.3610 | Yes |
| 9 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 390 | 2.432 | 0.3952 | Yes |
| 10 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 394 | 2.421 | 0.4293 | Yes |
| 11 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 1413 | 1.234 | 0.4192 | Yes |
| 12 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 1529 | 1.164 | 0.4326 | Yes |
| 13 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 1622 | 1.119 | 0.4459 | Yes |
| 14 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 1999 | 0.952 | 0.4492 | Yes |
| 15 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 2042 | 0.935 | 0.4613 | Yes |
| 16 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 2092 | 0.916 | 0.4729 | Yes |
| 17 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 2469 | 0.788 | 0.4739 | Yes |
| 18 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 3070 | 0.623 | 0.4665 | Yes |
| 19 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 3098 | 0.614 | 0.4744 | Yes |
| 20 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 3171 | 0.594 | 0.4809 | Yes |
| 21 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 3444 | 0.533 | 0.4810 | Yes |
| 22 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 3758 | 0.466 | 0.4792 | No |
| 23 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 4382 | 0.350 | 0.4673 | No |
| 24 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4415 | 0.345 | 0.4713 | No |
| 25 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 4858 | 0.266 | 0.4631 | No |
| 26 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 5212 | 0.209 | 0.4565 | No |
| 27 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 5314 | 0.192 | 0.4565 | No |
| 28 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 5830 | 0.105 | 0.4440 | No |
| 29 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 5966 | 0.091 | 0.4417 | No |
| 30 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 5980 | 0.089 | 0.4426 | No |
| 31 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 6167 | 0.061 | 0.4384 | No |
| 32 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6609 | 0.000 | 0.4265 | No |
| 33 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6626 | 0.000 | 0.4260 | No |
| 34 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 7130 | 0.000 | 0.4124 | No |
| 35 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7651 | 0.000 | 0.3984 | No |
| 36 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 7984 | 0.000 | 0.3894 | No |
| 37 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 8082 | 0.000 | 0.3868 | No |
| 38 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 8296 | 0.000 | 0.3810 | No |
| 39 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8538 | 0.000 | 0.3745 | No |
| 40 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8586 | 0.000 | 0.3732 | No |
| 41 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 9690 | 0.000 | 0.3434 | No |
| 42 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9698 | 0.000 | 0.3432 | No |
| 43 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9781 | 0.000 | 0.3409 | No |
| 44 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9988 | 0.000 | 0.3354 | No |
| 45 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 10058 | 0.000 | 0.3335 | No |
| 46 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 10157 | 0.000 | 0.3309 | No |
| 47 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10557 | 0.000 | 0.3201 | No |
| 48 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11572 | 0.000 | 0.2926 | No |
| 49 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11675 | 0.000 | 0.2899 | No |
| 50 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11682 | 0.000 | 0.2897 | No |
| 51 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11700 | 0.000 | 0.2892 | No |
| 52 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 12007 | 0.000 | 0.2810 | No |
| 53 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 12031 | 0.000 | 0.2803 | No |
| 54 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 12055 | 0.000 | 0.2797 | No |
| 55 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12446 | 0.000 | 0.2692 | No |
| 56 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12771 | 0.000 | 0.2604 | No |
| 57 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12892 | 0.000 | 0.2571 | No |
| 58 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 12950 | 0.000 | 0.2556 | No |
| 59 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 13345 | 0.000 | 0.2449 | No |
| 60 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13574 | 0.000 | 0.2388 | No |
| 61 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13582 | 0.000 | 0.2386 | No |
| 62 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13671 | 0.000 | 0.2362 | No |
| 63 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13906 | 0.000 | 0.2299 | No |
| 64 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 13987 | 0.000 | 0.2277 | No |
| 65 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14299 | 0.000 | 0.2193 | No |
| 66 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14618 | 0.000 | 0.2107 | No |
| 67 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 15989 | 0.000 | 0.1736 | No |
| 68 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 16086 | 0.000 | 0.1710 | No |
| 69 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 16113 | 0.000 | 0.1703 | No |
| 70 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16275 | 0.000 | 0.1660 | No |
| 71 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16358 | 0.000 | 0.1637 | No |
| 72 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17535 | 0.000 | 0.1319 | No |
| 73 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17607 | 0.000 | 0.1300 | No |
| 74 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 17775 | 0.000 | 0.1255 | No |
| 75 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17865 | 0.000 | 0.1231 | No |
| 76 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17875 | 0.000 | 0.1228 | No |
| 77 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18233 | 0.000 | 0.1132 | No |
| 78 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18239 | 0.000 | 0.1130 | No |
| 79 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18951 | 0.000 | 0.0938 | No |
| 80 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18969 | 0.000 | 0.0933 | No |
| 81 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19084 | 0.000 | 0.0902 | No |
| 82 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19105 | 0.000 | 0.0897 | No |
| 83 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19170 | 0.000 | 0.0880 | No |
| 84 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19310 | 0.000 | 0.0842 | No |
| 85 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19804 | 0.000 | 0.0709 | No |
| 86 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 19978 | 0.000 | 0.0662 | No |
| 87 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 20131 | 0.000 | 0.0621 | No |
| 88 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 20506 | 0.000 | 0.0520 | No |
| 89 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 20694 | 0.000 | 0.0469 | No |
| 90 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21207 | 0.000 | 0.0330 | No |
| 91 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 21959 | 0.000 | 0.0127 | No |
| 92 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 21960 | 0.000 | 0.0127 | No |
| 93 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 22095 | 0.000 | 0.0091 | No |
| 94 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 23009 | 0.000 | -0.0156 | No |
| 95 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 23523 | 0.000 | -0.0295 | No |
| 96 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 23862 | 0.000 | -0.0386 | No |
| 97 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23866 | 0.000 | -0.0387 | No |
| 98 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 24018 | 0.000 | -0.0428 | No |
| 99 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 24034 | 0.000 | -0.0432 | No |
| 100 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 24413 | 0.000 | -0.0534 | No |
| 101 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 24908 | 0.000 | -0.0668 | No |
| 102 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24974 | 0.000 | -0.0686 | No |
| 103 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 25438 | 0.000 | -0.0811 | No |
| 104 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 26136 | 0.000 | -0.1000 | No |
| 105 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 26744 | 0.000 | -0.1164 | No |
| 106 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 26750 | 0.000 | -0.1165 | No |
| 107 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 27149 | 0.000 | -0.1273 | No |
| 108 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 27325 | 0.000 | -0.1320 | No |
| 109 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 27347 | 0.000 | -0.1326 | No |
| 110 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 28107 | -0.070 | -0.1521 | No |
| 111 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 28220 | -0.085 | -0.1540 | No |
| 112 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 28399 | -0.110 | -0.1572 | No |
| 113 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 28515 | -0.126 | -0.1586 | No |
| 114 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 28923 | -0.179 | -0.1670 | No |
| 115 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 29194 | -0.212 | -0.1713 | No |
| 116 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 29316 | -0.230 | -0.1714 | No |
| 117 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 29382 | -0.235 | -0.1698 | No |
| 118 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 29752 | -0.287 | -0.1757 | No |
| 119 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 29886 | -0.307 | -0.1750 | No |
| 120 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 32509 | -0.774 | -0.2350 | No |
| 121 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 32586 | -0.793 | -0.2258 | No |
| 122 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 33028 | -0.908 | -0.2249 | No |
| 123 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 33265 | -0.967 | -0.2176 | No |
| 124 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 33335 | -0.986 | -0.2055 | No |
| 125 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 34019 | -1.196 | -0.2071 | No |
| 126 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 34296 | -1.291 | -0.1963 | No |
| 127 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 34674 | -1.464 | -0.1858 | No |
| 128 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 34976 | -1.599 | -0.1714 | No |
| 129 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 34985 | -1.604 | -0.1489 | No |
| 130 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 35062 | -1.651 | -0.1276 | No |
| 131 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 35577 | -1.970 | -0.1136 | No |
| 132 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 35856 | -2.178 | -0.0904 | No |
| 133 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 36129 | -2.411 | -0.0636 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36561 | -2.929 | -0.0339 | No |
| 135 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 36805 | -3.406 | 0.0077 | No |
