Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetKRAS.LUNG.BREAST_UP.V1_UP
Enrichment Score (ES)0.59223056
Normalized Enrichment Score (NES)1.5734544
Nominal p-value0.0
FDR q-value0.04896766
FWER p-Value0.051
Table: GSEA Results Summary



Fig 1: Enrichment plot: KRAS.LUNG.BREAST_UP.V1_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTGS2prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]44.9390.0533Yes
2CSF3colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438]114.8220.1053Yes
3IL1RL1interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998]454.2490.1504Yes
4TRAF1TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031]683.9730.1928Yes
5ETS1ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]893.7380.2326Yes
6GLRXglutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330]923.7360.2730Yes
7LIFLIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596]1933.1440.3043Yes
8IL13RA2interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975]2212.9900.3359Yes
9ISG20interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130]2412.8960.3667Yes
10TNFAIP3TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896]2552.8480.3972Yes
11FCRL2Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875]2702.7630.4267Yes
12DHRS9dehydrogenase/reductase 9 [Source:HGNC Symbol;Acc:HGNC:16888]2802.7430.4561Yes
13ID2inhibitor of DNA binding 2 [Source:HGNC Symbol;Acc:HGNC:5361]4022.4100.4789Yes
14DOCK4dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192]4352.3180.5031Yes
15POLMDNA polymerase mu [Source:HGNC Symbol;Acc:HGNC:9185]4652.2490.5267Yes
16MMP9matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176]7191.8380.5397Yes
17ADAM8ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215]10501.4860.5468Yes
18CXCL2C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603]11841.3920.5583Yes
19PRDM1PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346]14611.2020.5638Yes
20GPR4G protein-coupled receptor 4 [Source:HGNC Symbol;Acc:HGNC:4497]15801.1370.5730Yes
21SPRY2sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270]16411.1110.5833Yes
22TNFSF15TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931]17371.0590.5922Yes
23HBEGFheparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059]23260.8330.5853No
24ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080]24560.7920.5904No
25ZNF639zinc finger protein 639 [Source:HGNC Symbol;Acc:HGNC:30950]32920.5650.5739No
26MYH2myosin heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:7572]36360.4900.5699No
27RREB1ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]38350.4510.5695No
28CXCL3C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604]40870.4070.5671No
29OSBP2oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]41580.3940.5694No
30A2Malpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]41950.3890.5727No
31SH2D2ASH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821]42340.3810.5758No
32LAT2linker for activation of T cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]45800.3180.5699No
33ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6 [Source:HGNC Symbol;Acc:HGNC:222]50940.2250.5584No
34MMP10matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156]55210.1550.5486No
35RPS4Y1ribosomal protein S4 Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:10425]55680.1460.5489No
36INHBAinhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066]59650.0910.5392No
37NAV3neuron navigator 3 [Source:HGNC Symbol;Acc:HGNC:15998]62520.0470.5319No
38CD37CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666]63370.0300.5300No
39CCL20C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619]66090.0000.5227No
40SCG5secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816]67520.0000.5188No
41RNASE1ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044]74540.0000.4998No
42SLCO5A1solute carrier organic anion transporter family member 5A1 [Source:HGNC Symbol;Acc:HGNC:19046]74740.0000.4993No
43CD247CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677]83230.0000.4764No
44SHOXshort stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853]83740.0000.4750No
45CALB1calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434]89740.0000.4588No
46CLSTN2calsyntenin 2 [Source:HGNC Symbol;Acc:HGNC:17448]90850.0000.4558No
47ADAM19ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]101220.0000.4278No
48FAM174Bfamily with sequence similarity 174 member B [Source:HGNC Symbol;Acc:HGNC:34339]106670.0000.4131No
49PPBPpro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240]111540.0000.3999No
50TFDP3transcription factor Dp family member 3 [Source:HGNC Symbol;Acc:HGNC:24603]113650.0000.3942No
51TSPAN1tetraspanin 1 [Source:HGNC Symbol;Acc:HGNC:20657]116960.0000.3853No
52CLPScolipase [Source:HGNC Symbol;Acc:HGNC:2085]118590.0000.3809No
53IGFBP3insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]119500.0000.3785No
54ESM1endothelial cell specific molecule 1 [Source:HGNC Symbol;Acc:HGNC:3466]120600.0000.3755No
55TAAR5trace amine associated receptor 5 [Source:HGNC Symbol;Acc:HGNC:30236]127440.0000.3571No
56GBA3glucosylceramidase beta 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:19069]128510.0000.3542No
57RBP4retinol binding protein 4 [Source:HGNC Symbol;Acc:HGNC:9922]129950.0000.3503No
58RBMXL2RBMX like 2 [Source:HGNC Symbol;Acc:HGNC:17886]131220.0000.3469No
59GULP1GULP PTB domain containing engulfment adaptor 1 [Source:HGNC Symbol;Acc:HGNC:18649]132910.0000.3424No
60HOXD11homeobox D11 [Source:HGNC Symbol;Acc:HGNC:5134]133620.0000.3405No
61OR2B6olfactory receptor family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:8241]136150.0000.3336No
62KIAA1549LKIAA1549 like [Source:HGNC Symbol;Acc:HGNC:24836]138280.0000.3279No
63RELNreelin [Source:HGNC Symbol;Acc:HGNC:9957]139540.0000.3245No
64IL37interleukin 37 [Source:HGNC Symbol;Acc:HGNC:15563]139690.0000.3242No
65RETNresistin [Source:HGNC Symbol;Acc:HGNC:20389]140660.0000.3216No
66HSD11B1hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208]145200.0000.3093No
67ZP4zona pellucida glycoprotein 4 [Source:HGNC Symbol;Acc:HGNC:15770]148940.0000.2992No
68SPINK1serine peptidase inhibitor Kazal type 1 [Source:HGNC Symbol;Acc:HGNC:11244]155490.0000.2815No
69G0S2G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229]159100.0000.2718No
70IL1R2interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994]159870.0000.2697No
71IL23Ainterleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488]159890.0000.2697No
72AMELYamelogenin Y-linked [Source:HGNC Symbol;Acc:HGNC:462]160900.0000.2670No
73MGLLmonoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038]172160.0000.2365No
74GRPgastrin releasing peptide [Source:HGNC Symbol;Acc:HGNC:4605]172180.0000.2365No
75CEACAM3CEA cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:1815]179350.0000.2171No
76IGHV3-48immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606]182840.0000.2077No
77BMP6bone morphogenetic protein 6 [Source:HGNC Symbol;Acc:HGNC:1073]191020.0000.1856No
78MMP1matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155]191330.0000.1848No
79NRLneural retina leucine zipper [Source:HGNC Symbol;Acc:HGNC:8002]194130.0000.1772No
80CXCL8C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]194790.0000.1755No
81CXCL1C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602]194880.0000.1752No
82CXCL5C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642]194900.0000.1752No
83TBX3T-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11602]197520.0000.1682No
84HSD17B2hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211]198040.0000.1668No
85GABRA3gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077]200030.0000.1614No
86NR1H4nuclear receptor subfamily 1 group H member 4 [Source:HGNC Symbol;Acc:HGNC:7967]200040.0000.1614No
87PRLprolactin [Source:HGNC Symbol;Acc:HGNC:9445]201370.0000.1578No
88PRYPTPN13 like Y-linked [Source:HGNC Symbol;Acc:HGNC:14024]201440.0000.1577No
89TERTtelomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730]204630.0000.1491No
90KRT34keratin 34 [Source:HGNC Symbol;Acc:HGNC:6452]220510.0000.1061No
91CRCT1cysteine rich C-terminal 1 [Source:HGNC Symbol;Acc:HGNC:29875]222530.0000.1007No
92RMSTrhabdomyosarcoma 2 associated transcript [Source:HGNC Symbol;Acc:HGNC:29893]223390.0000.0984No
93CMKLR1chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]225060.0000.0939No
94CD1ACD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634]231020.0000.0778No
95CCR6C-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:1607]231420.0000.0767No
96NELL2neural EGFL like 2 [Source:HGNC Symbol;Acc:HGNC:7751]237840.0000.0594No
97SLC25A31solute carrier family 25 member 31 [Source:HGNC Symbol;Acc:HGNC:25319]237860.0000.0594No
98NPPBnatriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940]238660.0000.0572No
99TSPY1testis specific protein Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:12381]239650.0000.0546No
100SNAP25synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132]243430.0000.0444No
101KCNK15potassium two pore domain channel subfamily K member 15 [Source:HGNC Symbol;Acc:HGNC:13814]244240.0000.0422No
102DNAH9dynein axonemal heavy chain 9 [Source:HGNC Symbol;Acc:HGNC:2953]245950.0000.0376No
103FAM155Bfamily with sequence similarity 155 member B [Source:HGNC Symbol;Acc:HGNC:30701]246160.0000.0371No
104CSF2colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434]247000.0000.0348No
105SNAP91synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986]248670.0000.0303No
106IFNA8interferon alpha 8 [Source:HGNC Symbol;Acc:HGNC:5429]248830.0000.0299No
107CHRNA2cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956]249640.0000.0277No
108HAS2hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819]251100.0000.0238No
109PTPRRprotein tyrosine phosphatase receptor type R [Source:HGNC Symbol;Acc:HGNC:9680]252440.0000.0202No
110TTC22tetratricopeptide repeat domain 22 [Source:HGNC Symbol;Acc:HGNC:26067]254950.0000.0135No
111PRSS3serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486]255650.0000.0116No
112SMPXsmall muscle protein X-linked [Source:HGNC Symbol;Acc:HGNC:11122]256990.0000.0080No
113PDCD1LG2programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731]257950.0000.0054No
114FNDC8fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286]260720.000-0.0020No
115ITGA2integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137]266570.000-0.0179No
116STC1stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373]276020.000-0.0434No
117BIRC3baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591]27956-0.045-0.0525No
118AKT2AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392]28147-0.075-0.0568No
119SEMA3Bsemaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724]28715-0.152-0.0705No
120HPNhepsin [Source:HGNC Symbol;Acc:HGNC:5155]28844-0.172-0.0721No
121LDB3LIM domain binding 3 [Source:HGNC Symbol;Acc:HGNC:15710]29142-0.204-0.0779No
122OSGIN1oxidative stress induced growth inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:30093]29512-0.251-0.0852No
123MKRN3makorin ring finger protein 3 [Source:HGNC Symbol;Acc:HGNC:7114]30408-0.390-0.1052No
124KIF5Ckinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325]32031-0.677-0.1418No
125GFI1growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237]32514-0.775-0.1464No
126TAGLN3transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]33040-0.911-0.1508No
127NDOR1NADPH dependent diflavin oxidoreductase 1 [Source:HGNC Symbol;Acc:HGNC:29838]33361-0.995-0.1487No
128KCNJ14potassium inwardly rectifying channel subfamily J member 14 [Source:HGNC Symbol;Acc:HGNC:6260]33469-1.022-0.1405No
129KCNC2potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234]33598-1.055-0.1326No
130PDE2Aphosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]33858-1.136-0.1273No
131LILRA6leukocyte immunoglobulin like receptor A6 [Source:HGNC Symbol;Acc:HGNC:15495]33916-1.158-0.1163No
132CDSNcorneodesmosin [Source:HGNC Symbol;Acc:HGNC:1802]34142-1.233-0.1091No
133CTNNA2catenin alpha 2 [Source:HGNC Symbol;Acc:HGNC:2510]34493-1.377-0.1037No
134ITPKAinositol-trisphosphate 3-kinase A [Source:HGNC Symbol;Acc:HGNC:6178]34497-1.379-0.0888No
135ANGPTL4angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]34518-1.388-0.0744No
136CCDC181coiled-coil domain containing 181 [Source:HGNC Symbol;Acc:HGNC:28051]34765-1.508-0.0647No
137ATG10autophagy related 10 [Source:HGNC Symbol;Acc:HGNC:20315]34818-1.533-0.0495No
138KCNC1potassium voltage-gated channel subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:6233]35556-1.949-0.0484No
139SLCO4A1solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953]36057-2.343-0.0366No
140GYPCglycophorin C (Gerbich blood group) [Source:HGNC Symbol;Acc:HGNC:4704]36077-2.358-0.0116No
141KIF5Akinesin family member 5A [Source:HGNC Symbol;Acc:HGNC:6323]36876-3.6030.0058No
Table: GSEA details [plain text format]



Fig 2: KRAS.LUNG.BREAST_UP.V1_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KRAS.LUNG.BREAST_UP.V1_UP: Random ES distribution   
Gene set null distribution of ES for KRAS.LUNG.BREAST_UP.V1_UP