Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_NA
GeneSetKRAS.PROSTATE_UP.V1_DN
Enrichment Score (ES)-0.5939737
Normalized Enrichment Score (NES)-1.2999904
Nominal p-value0.03003337
FDR q-value0.22805275
FWER p-Value0.992
Table: GSEA Results Summary



Fig 1: Enrichment plot: KRAS.PROSTATE_UP.V1_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EDN1endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176]474.2370.0595No
2SERPINB2serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584]1103.6230.1098No
3CCDC134coiled-coil domain containing 134 [Source:HGNC Symbol;Acc:HGNC:26185]9251.5940.1106No
4KDM8lysine demethylase 8 [Source:HGNC Symbol;Acc:HGNC:25840]11651.4090.1244No
5TGM1transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777]24060.8080.1024No
6CA5Bcarbonic anhydrase 5B [Source:HGNC Symbol;Acc:HGNC:1378]27870.7020.1022No
7CCR10C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474]33420.5560.0952No
8PTGISprostaglandin I2 synthase [Source:HGNC Symbol;Acc:HGNC:9603]35190.5150.0978No
9DZANK1double zinc ribbon and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15858]36810.4820.1003No
10CGREF1cell growth regulator with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:16962]38760.4440.1015No
11CRY2cryptochrome circadian regulator 2 [Source:HGNC Symbol;Acc:HGNC:2385]44510.3370.0908No
12RAI1retinoic acid induced 1 [Source:HGNC Symbol;Acc:HGNC:9834]44680.3360.0951No
13ITGB7integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162]44870.3320.0994No
14MAOBmonoamine oxidase B [Source:HGNC Symbol;Acc:HGNC:6834]49570.2470.0903No
15SLC30A4solute carrier family 30 member 4 [Source:HGNC Symbol;Acc:HGNC:11015]54440.1700.0796No
16C5complement C5 [Source:HGNC Symbol;Acc:HGNC:1331]62150.0540.0595No
17LHCGRluteinizing hormone/choriogonadotropin receptor [Source:HGNC Symbol;Acc:HGNC:6585]66440.0000.0479No
18CWH43cell wall biogenesis 43 C-terminal homolog [Source:HGNC Symbol;Acc:HGNC:26133]71430.0000.0344No
19CRYGDcrystallin gamma D [Source:HGNC Symbol;Acc:HGNC:2411]74190.0000.0270No
20C22orf31chromosome 22 open reading frame 31 [Source:HGNC Symbol;Acc:HGNC:26931]74300.0000.0267No
21ARG1arginase 1 [Source:HGNC Symbol;Acc:HGNC:663]75140.0000.0245No
22EPHB6EPH receptor B6 [Source:HGNC Symbol;Acc:HGNC:3396]76440.0000.0210No
23ASIPagouti signaling protein [Source:HGNC Symbol;Acc:HGNC:745]78670.0000.0150No
24EPHX2epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402]81470.0000.0074No
25TFAP2Btranscription factor AP-2 beta [Source:HGNC Symbol;Acc:HGNC:11743]84180.0000.0001No
26COLEC10collectin subfamily member 10 [Source:HGNC Symbol;Acc:HGNC:2220]86510.000-0.0062No
27S100A8S100 calcium binding protein A8 [Source:HGNC Symbol;Acc:HGNC:10498]87570.000-0.0090No
28S100A7S100 calcium binding protein A7 [Source:HGNC Symbol;Acc:HGNC:10497]87600.000-0.0091No
29CNTFRciliary neurotrophic factor receptor [Source:HGNC Symbol;Acc:HGNC:2170]89920.000-0.0153No
30SOX10SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190]90120.000-0.0158No
31KCNA2potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]99030.000-0.0399No
32ADAM23ADAM metallopeptidase domain 23 [Source:HGNC Symbol;Acc:HGNC:202]99130.000-0.0401No
33KCNQ2potassium voltage-gated channel subfamily Q member 2 [Source:HGNC Symbol;Acc:HGNC:6296]100510.000-0.0439No
34SPRR1Asmall proline rich protein 1A [Source:HGNC Symbol;Acc:HGNC:11259]103830.000-0.0528No
35SPRR1Bsmall proline rich protein 1B [Source:HGNC Symbol;Acc:HGNC:11260]103860.000-0.0529No
36LCN2lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526]111120.000-0.0725No
37ACKR3atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692]112780.000-0.0770No
38KLKB1kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]113250.000-0.0782No
39BEND5BEN domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25668]116610.000-0.0873No
40SSTR4somatostatin receptor 4 [Source:HGNC Symbol;Acc:HGNC:11333]118090.000-0.0912No
41NPHS1NPHS1 adhesion molecule, nephrin [Source:HGNC Symbol;Acc:HGNC:7908]118340.000-0.0919No
42IGFBP3insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]119500.000-0.0950No
43ATP8B3ATPase phospholipid transporting 8B3 [Source:HGNC Symbol;Acc:HGNC:13535]119620.000-0.0953No
44SLC6A14solute carrier family 6 member 14 [Source:HGNC Symbol;Acc:HGNC:11047]120110.000-0.0966No
45MLANAmelan-A [Source:HGNC Symbol;Acc:HGNC:7124]121780.000-0.1011No
46ARL17AADP ribosylation factor like GTPase 17A [Source:HGNC Symbol;Acc:HGNC:24096]123020.000-0.1044No
47TRHthyrotropin releasing hormone [Source:HGNC Symbol;Acc:HGNC:12298]128260.000-0.1186No
48MUC4mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514]129650.000-0.1223No
49TUBAL3tubulin alpha like 3 [Source:HGNC Symbol;Acc:HGNC:23534]133060.000-0.1315No
50IL19interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5990]139260.000-0.1483No
51TAGLNtransgelin [Source:HGNC Symbol;Acc:HGNC:11553]139390.000-0.1486No
52KRT4keratin 4 [Source:HGNC Symbol;Acc:HGNC:6441]142950.000-0.1582No
53VGLL3vestigial like family member 3 [Source:HGNC Symbol;Acc:HGNC:24327]143900.000-0.1607No
54RGS6regulator of G protein signaling 6 [Source:HGNC Symbol;Acc:HGNC:10002]148610.000-0.1735No
55ARHGAP28Rho GTPase activating protein 28 [Source:HGNC Symbol;Acc:HGNC:25509]152720.000-0.1846No
56ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:3356]157860.000-0.1984No
57CFIcomplement factor I [Source:HGNC Symbol;Acc:HGNC:5394]158710.000-0.2007No
58IGLV2-14immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888]162970.000-0.2122No
59PPP1R9Aprotein phosphatase 1 regulatory subunit 9A [Source:HGNC Symbol;Acc:HGNC:14946]177840.000-0.2524No
60NPBWR2neuropeptides B and W receptor 2 [Source:HGNC Symbol;Acc:HGNC:4530]180990.000-0.2609No
61CDH16cadherin 16 [Source:HGNC Symbol;Acc:HGNC:1755]187650.000-0.2789No
62LUMlumican [Source:HGNC Symbol;Acc:HGNC:6724]187990.000-0.2798No
63GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type [Source:HGNC Symbol;Acc:HGNC:4205]192580.000-0.2922No
64NDPnorrin cystine knot growth factor NDP [Source:HGNC Symbol;Acc:HGNC:7678]192950.000-0.2932No
65IBSPintegrin binding sialoprotein [Source:HGNC Symbol;Acc:HGNC:5341]196780.000-0.3035No
66OXToxytocin/neurophysin I prepropeptide [Source:HGNC Symbol;Acc:HGNC:8528]198650.000-0.3086No
67FLRT1fibronectin leucine rich transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3760]199260.000-0.3102No
68PI3peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947]200340.000-0.3131No
69PRYPTPN13 like Y-linked [Source:HGNC Symbol;Acc:HGNC:14024]201440.000-0.3160No
70KLF1Kruppel like factor 1 [Source:HGNC Symbol;Acc:HGNC:6345]206760.000-0.3304No
71SPRR3small proline rich protein 3 [Source:HGNC Symbol;Acc:HGNC:11268]207310.000-0.3319No
72SDSserine dehydratase [Source:HGNC Symbol;Acc:HGNC:10691]208610.000-0.3354No
73ARPP21cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968]210050.000-0.3392No
74ZNF750zinc finger protein 750 [Source:HGNC Symbol;Acc:HGNC:25843]210920.000-0.3416No
75FOLH1Bfolate hydrolase 1B [Source:HGNC Symbol;Acc:HGNC:13636]212690.000-0.3463No
76GKN1gastrokine 1 [Source:HGNC Symbol;Acc:HGNC:23217]215130.000-0.3529No
77KRT13keratin 13 [Source:HGNC Symbol;Acc:HGNC:6415]220870.000-0.3684No
78KRT16keratin 16 [Source:HGNC Symbol;Acc:HGNC:6423]220960.000-0.3686No
79KIAA0087KIAA0087 lncRNA [Source:HGNC Symbol;Acc:HGNC:22191]229250.000-0.3910No
80NCR3natural cytotoxicity triggering receptor 3 [Source:HGNC Symbol;Acc:HGNC:19077]231630.000-0.3974No
81CD48CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683]231650.000-0.3975No
82CD96CD96 molecule [Source:HGNC Symbol;Acc:HGNC:16892]232290.000-0.3992No
83SLC19A3solute carrier family 19 member 3 [Source:HGNC Symbol;Acc:HGNC:16266]232900.000-0.4008No
84COBLcordon-bleu WH2 repeat protein [Source:HGNC Symbol;Acc:HGNC:22199]234230.000-0.4044No
85ACSS3acyl-CoA synthetase short chain family member 3 [Source:HGNC Symbol;Acc:HGNC:24723]240520.000-0.4214No
86MUC16mucin 16, cell surface associated [Source:HGNC Symbol;Acc:HGNC:15582]245330.000-0.4344No
87C1orf68chromosome 1 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:29468]245360.000-0.4344No
88MAGIXMAGI family member, X-linked [Source:HGNC Symbol;Acc:HGNC:30006]248280.000-0.4423No
89CLDN17claudin 17 [Source:HGNC Symbol;Acc:HGNC:2038]249000.000-0.4442No
90NTF3neurotrophin 3 [Source:HGNC Symbol;Acc:HGNC:8023]251060.000-0.4498No
91PTPRHprotein tyrosine phosphatase receptor type H [Source:HGNC Symbol;Acc:HGNC:9672]252490.000-0.4536No
92HBA2hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824]252590.000-0.4538No
93PRTN3proteinase 3 [Source:HGNC Symbol;Acc:HGNC:9495]258660.000-0.4702No
94SOD3superoxide dismutase 3 [Source:HGNC Symbol;Acc:HGNC:11181]262160.000-0.4797No
95REEP1receptor accessory protein 1 [Source:HGNC Symbol;Acc:HGNC:25786]268460.000-0.4967No
96ZBTB16zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:12930]271060.000-0.5037No
97DIRAS3DIRAS family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:687]272250.000-0.5069No
98PLGLAplasminogen like A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:9074]273170.000-0.5094No
99PF4V1platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862]273410.000-0.5100No
100ITGB1BP2integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154]27957-0.045-0.5260No
101FOXD2forkhead box D2 [Source:HGNC Symbol;Acc:HGNC:3803]28060-0.062-0.5279No
102GPRASP1G protein-coupled receptor associated sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:24834]28075-0.064-0.5273No
103PCDHB13protocadherin beta 13 [Source:HGNC Symbol;Acc:HGNC:8684]28275-0.092-0.5314No
104YBX2Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948]28342-0.102-0.5317No
105NEU3neuraminidase 3 [Source:HGNC Symbol;Acc:HGNC:7760]28484-0.121-0.5338No
106PLCB1phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917]28568-0.134-0.5341No
107FBXO40F-box protein 40 [Source:HGNC Symbol;Acc:HGNC:29816]28588-0.136-0.5327No
108SLC26A10solute carrier family 26 member 10 [Source:HGNC Symbol;Acc:HGNC:14470]28692-0.148-0.5333No
109GRM2glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594]29194-0.212-0.5439No
110HLA-DMBmajor histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935]29327-0.230-0.5441No
111SERHLserine hydrolase like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:14408]29671-0.276-0.5495No
112RASGRP1RAS guanyl releasing protein 1 [Source:HGNC Symbol;Acc:HGNC:9878]29733-0.284-0.5470No
113SLC4A8solute carrier family 4 member 8 [Source:HGNC Symbol;Acc:HGNC:11034]30444-0.395-0.5606No
114EGFepidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229]30714-0.434-0.5616No
115VIL1villin 1 [Source:HGNC Symbol;Acc:HGNC:12690]30785-0.444-0.5572No
116SERPINB7serpin family B member 7 [Source:HGNC Symbol;Acc:HGNC:13902]30983-0.477-0.5556No
117CTSEcathepsin E [Source:HGNC Symbol;Acc:HGNC:2530]31431-0.556-0.5598No
118AK5adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365]31820-0.630-0.5612No
119ABCB1ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]32708-0.826-0.5734No
120KCNJ14potassium inwardly rectifying channel subfamily J member 14 [Source:HGNC Symbol;Acc:HGNC:6260]33469-1.022-0.5793Yes
121SMOsmoothened, frizzled class receptor [Source:HGNC Symbol;Acc:HGNC:11119]33680-1.086-0.5694Yes
122DNAJC12DnaJ heat shock protein family (Hsp40) member C12 [Source:HGNC Symbol;Acc:HGNC:28908]33886-1.146-0.5585Yes
123CADM4cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:30825]33940-1.167-0.5432Yes
124POU3F2POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9215]34135-1.233-0.5308Yes
125MAFBMAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408]34616-1.433-0.5232Yes
126TUBB4Atubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774]34808-1.529-0.5065Yes
127TTC21Btetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]35224-1.736-0.4928Yes
128IDUAalpha-L-iduronidase [Source:HGNC Symbol;Acc:HGNC:5391]35287-1.780-0.4689Yes
129SCELsciellin [Source:HGNC Symbol;Acc:HGNC:10573]35494-1.908-0.4471Yes
130MLYCDmalonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150]35539-1.936-0.4206Yes
131CAMK1Dcalcium/calmodulin dependent protein kinase ID [Source:HGNC Symbol;Acc:HGNC:19341]35542-1.940-0.3928Yes
132GNGT2G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412]35579-1.972-0.3655Yes
133NR0B2nuclear receptor subfamily 0 group B member 2 [Source:HGNC Symbol;Acc:HGNC:7961]35707-2.062-0.3393Yes
134PTH1Rparathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608]36131-2.414-0.3162Yes
135ABCG4ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884]36246-2.532-0.2829Yes
136RRADRRAD, Ras related glycolysis inhibitor and calcium channel regulator [Source:HGNC Symbol;Acc:HGNC:10446]36489-2.835-0.2488Yes
137NOS1nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872]36541-2.894-0.2087Yes
138OPCMLopioid binding protein/cell adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:8143]36804-3.405-0.1669Yes
139GPNMBglycoprotein nmb [Source:HGNC Symbol;Acc:HGNC:4462]36825-3.459-0.1178Yes
140SH2D3CSH2 domain containing 3C [Source:HGNC Symbol;Acc:HGNC:16884]36964-3.892-0.0657Yes
141AATKapoptosis associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:21]37080-4.8190.0003Yes
Table: GSEA details [plain text format]



Fig 2: KRAS.PROSTATE_UP.V1_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KRAS.PROSTATE_UP.V1_DN: Random ES distribution   
Gene set null distribution of ES for KRAS.PROSTATE_UP.V1_DN