Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetP53_DN.V2_UP
Enrichment Score (ES)0.49138755
Normalized Enrichment Score (NES)1.2874985
Nominal p-value0.04347826
FDR q-value0.113203995
FWER p-Value0.438
Table: GSEA Results Summary



Fig 1: Enrichment plot: P53_DN.V2_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IL1RNinterleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000]34.9520.0531Yes
2CCL4C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630]74.8610.1051Yes
3NFKBIANFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797]973.7120.1426Yes
4IER3immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392]1433.3750.1776Yes
5OSGIN2oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355]1593.2960.2125Yes
6CD83CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703]1733.2440.2470Yes
7MMP13matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]2382.9090.2765Yes
8TNFAIP3TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896]2552.8480.3066Yes
9FCRL2Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875]2702.7630.3359Yes
10P2RY6pyrimidinergic receptor P2Y6 [Source:HGNC Symbol;Acc:HGNC:8543]3762.4660.3595Yes
11FOSL2FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798]4462.2950.3823Yes
12SYN1synapsin I [Source:HGNC Symbol;Acc:HGNC:11494]5232.1360.4031Yes
13HAO1hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809]6671.9070.4197Yes
14CLCF1cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412]7181.8400.4381Yes
15IKZF1IKAROS family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13176]8881.6370.4511Yes
16CYP2C8cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]9451.5790.4665Yes
17PTK2Bprotein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612]10081.5220.4812Yes
18CXCL2C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603]11841.3920.4914Yes
19SDC4syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661]24650.7890.4652No
20EVI2Aecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499]26090.7450.4693No
21PRKCEprotein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401]26580.7290.4759No
22TUBB1tubulin beta 1 class VI [Source:HGNC Symbol;Acc:HGNC:16257]26860.7220.4829No
23NCKAP1LNCK associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:4862]28630.6780.4854No
24H2AC4H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734]31200.6090.4850No
25ANGPTL3angiopoietin like 3 [Source:HGNC Symbol;Acc:HGNC:491]34920.5200.4805No
26CH25Hcholesterol 25-hydroxylase [Source:HGNC Symbol;Acc:HGNC:1907]35350.5110.4849No
27PRRG3proline rich and Gla domain 3 [Source:HGNC Symbol;Acc:HGNC:30798]40370.4180.4758No
28MPZmyelin protein zero [Source:HGNC Symbol;Acc:HGNC:7225]45100.3290.4665No
29LRRC32leucine rich repeat containing 32 [Source:HGNC Symbol;Acc:HGNC:4161]47970.2750.4618No
30MT1Gmetallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399]49750.2440.4596No
31CD5LCD5 molecule like [Source:HGNC Symbol;Acc:HGNC:1690]54950.1590.4472No
32WNT3Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782]58020.1090.4401No
33SLC4A10solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811]60080.0850.4355No
34SLASrc like adaptor [Source:HGNC Symbol;Acc:HGNC:10902]60450.0800.4354No
35KCNMB1potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285]60690.0750.4355No
36SARDHsarcosine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:10536]61480.0640.4341No
37CCL20C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619]66090.0000.4217No
38FGF22fibroblast growth factor 22 [Source:HGNC Symbol;Acc:HGNC:3679]71140.0000.4080No
39PRDM11PR/SET domain 11 [Source:HGNC Symbol;Acc:HGNC:13996]71600.0000.4068No
40PPEF1protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]72140.0000.4054No
41C4BPAcomplement component 4 binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1325]74250.0000.3997No
42PKD2L1polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011]80320.0000.3833No
43PCDH1protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]83140.0000.3757No
44GUCY2Dguanylate cyclase 2D, retinal [Source:HGNC Symbol;Acc:HGNC:4689]86000.0000.3680No
45GPA33glycoprotein A33 [Source:HGNC Symbol;Acc:HGNC:4445]87240.0000.3646No
46BARX2BARX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:956]88020.0000.3626No
47CDH4cadherin 4 [Source:HGNC Symbol;Acc:HGNC:1763]96470.0000.3397No
48CLEC1AC-type lectin domain family 1 member A [Source:HGNC Symbol;Acc:HGNC:24355]96750.0000.3390No
49TNFRSF9TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924]99930.0000.3304No
50KCNK3potassium two pore domain channel subfamily K member 3 [Source:HGNC Symbol;Acc:HGNC:6278]100340.0000.3293No
51ADAM12ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190]101240.0000.3269No
52HS3ST2heparan sulfate-glucosamine 3-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:5195]101950.0000.3250No
53APOL3apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868]102670.0000.3231No
54GSC2goosecoid homeobox 2 [Source:HGNC Symbol;Acc:HGNC:4613]103510.0000.3208No
55SPRR2Csmall proline rich protein 2C (pseudogene) [Source:HGNC Symbol;Acc:HGNC:11263]103770.0000.3202No
56SPRR1Bsmall proline rich protein 1B [Source:HGNC Symbol;Acc:HGNC:11260]103860.0000.3199No
57CYP2D6cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625]105040.0000.3168No
58IL1RAPL1interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996]105910.0000.3145No
59RFPL2ret finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:9979]107100.0000.3113No
60NTRK3neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033]111300.0000.2999No
61GYPBglycophorin B (MNS blood group) [Source:HGNC Symbol;Acc:HGNC:4703]120280.0000.2756No
62NTSR1neurotensin receptor 1 [Source:HGNC Symbol;Acc:HGNC:8039]120350.0000.2755No
63LGSNlengsin, lens protein with glutamine synthetase domain [Source:HGNC Symbol;Acc:HGNC:21016]122920.0000.2685No
64PTX3pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692]125100.0000.2627No
65TNRtenascin R [Source:HGNC Symbol;Acc:HGNC:11953]127940.0000.2550No
66AVPR2arginine vasopressin receptor 2 [Source:HGNC Symbol;Acc:HGNC:897]128340.0000.2540No
67PCDHA6protocadherin alpha 6 [Source:HGNC Symbol;Acc:HGNC:8672]141000.0000.2197No
68ANXA10annexin A10 [Source:HGNC Symbol;Acc:HGNC:534]144320.0000.2108No
69TNNI3KTNNI3 interacting kinase [Source:HGNC Symbol;Acc:HGNC:19661]145880.0000.2066No
70SPINK1serine peptidase inhibitor Kazal type 1 [Source:HGNC Symbol;Acc:HGNC:11244]155490.0000.1806No
71HTR1E5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291]156860.0000.1769No
72BPIbactericidal permeability increasing protein [Source:HGNC Symbol;Acc:HGNC:1095]157090.0000.1763No
73IL36Ainterleukin 36 alpha [Source:HGNC Symbol;Acc:HGNC:15562]157310.0000.1757No
74CA3carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374]158120.0000.1736No
75AMELXamelogenin X-linked [Source:HGNC Symbol;Acc:HGNC:461]160890.0000.1661No
76FPR3formyl peptide receptor 3 [Source:HGNC Symbol;Acc:HGNC:3828]161900.0000.1634No
77RNF39ring finger protein 39 [Source:HGNC Symbol;Acc:HGNC:18064]166210.0000.1517No
78GP5glycoprotein V platelet [Source:HGNC Symbol;Acc:HGNC:4443]171930.0000.1363No
79SLC38A3solute carrier family 38 member 3 [Source:HGNC Symbol;Acc:HGNC:18044]176150.0000.1249No
80CEACAM5CEA cell adhesion molecule 5 [Source:HGNC Symbol;Acc:HGNC:1817]179410.0000.1161No
81DPYSdihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]181300.0000.1110No
82CHST8carbohydrate sulfotransferase 8 [Source:HGNC Symbol;Acc:HGNC:15993]181570.0000.1103No
83BFSP2beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041]182490.0000.1078No
84CXCL12C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672]189520.0000.0888No
85MOGmyelin oligodendrocyte glycoprotein [Source:HGNC Symbol;Acc:HGNC:7197]190380.0000.0865No
86MMP3matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173]191370.0000.0839No
87CXCL6C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643]194740.0000.0748No
88CXCL8C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]194790.0000.0747No
89CXCL1C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602]194880.0000.0745No
90CXCL5C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642]194900.0000.0744No
91CYP17A1cytochrome P450 family 17 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2593]198020.0000.0660No
92CHRNA10cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800]198050.0000.0660No
93PDCphosducin [Source:HGNC Symbol;Acc:HGNC:8759]199820.0000.0612No
94PYYpeptide YY [Source:HGNC Symbol;Acc:HGNC:9748]201820.0000.0558No
95RGRretinal G protein coupled receptor [Source:HGNC Symbol;Acc:HGNC:9990]205630.0000.0455No
96RHDRh blood group D antigen [Source:HGNC Symbol;Acc:HGNC:10009]205710.0000.0453No
97CACNG2calcium voltage-gated channel auxiliary subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:1406]206680.0000.0427No
98MMP17matrix metallopeptidase 17 [Source:HGNC Symbol;Acc:HGNC:7163]209360.0000.0355No
99TPTEtransmembrane phosphatase with tensin homology [Source:HGNC Symbol;Acc:HGNC:12023]210960.0000.0312No
100P2RY11purinergic receptor P2Y11 [Source:HGNC Symbol;Acc:HGNC:8540]214560.0000.0215No
101SLC16A4solute carrier family 16 member 4 [Source:HGNC Symbol;Acc:HGNC:10925]214770.0000.0209No
102SLC15A2solute carrier family 15 member 2 [Source:HGNC Symbol;Acc:HGNC:10921]219200.0000.0090No
103INSL3insulin like 3 [Source:HGNC Symbol;Acc:HGNC:6086]219570.0000.0080No
104INSL4insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087]219600.0000.0080No
105KRT31keratin 31 [Source:HGNC Symbol;Acc:HGNC:6448]220530.0000.0055No
106KRT14keratin 14 [Source:HGNC Symbol;Acc:HGNC:6416]220980.0000.0043No
107H1-6H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720]228910.000-0.0172No
108CTLA4cytotoxic T-lymphocyte associated protein 4 [Source:HGNC Symbol;Acc:HGNC:2505]229060.000-0.0175No
109CD69CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694]232210.000-0.0260No
110FOXL2forkhead box L2 [Source:HGNC Symbol;Acc:HGNC:1092]237520.000-0.0404No
111CYP2A13cytochrome P450 family 2 subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:2608]238450.000-0.0429No
112EVX1even-skipped homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3506]238890.000-0.0440No
113LALBAlactalbumin alpha [Source:HGNC Symbol;Acc:HGNC:6480]241600.000-0.0514No
114PRTN3proteinase 3 [Source:HGNC Symbol;Acc:HGNC:9495]258660.000-0.0975No
115RIPK4receptor interacting serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:496]259910.000-0.1009No
116OR10H3olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174]260010.000-0.1011No
117POU2AF1POU class 2 homeobox associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211]266770.000-0.1194No
118MAGEC2MAGE family member C2 [Source:HGNC Symbol;Acc:HGNC:13574]269410.000-0.1265No
119PF4V1platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862]273410.000-0.1373No
120XAF1XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932]274830.000-0.1411No
121ATP12AATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816]28159-0.076-0.1586No
122DLX6distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGNC:2919]28472-0.120-0.1657No
123RELBRELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956]28505-0.125-0.1653No
124RORCRAR related orphan receptor C [Source:HGNC Symbol;Acc:HGNC:10260]28514-0.126-0.1641No
125RFX2regulatory factor X2 [Source:HGNC Symbol;Acc:HGNC:9983]28985-0.183-0.1749No
126OSGIN1oxidative stress induced growth inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:30093]29512-0.251-0.1864No
127ITM2Aintegral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173]30272-0.368-0.2030No
128TP53tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998]30478-0.399-0.2043No
129CNOT9CCR4-NOT transcription complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:10445]30507-0.402-0.2007No
130TDRKHtudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713]31233-0.516-0.2148No
131INPP5Dinositol polyphosphate-5-phosphatase D [Source:HGNC Symbol;Acc:HGNC:6079]31965-0.663-0.2275No
132BAXBCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]32076-0.684-0.2231No
133NF1neurofibromin 1 [Source:HGNC Symbol;Acc:HGNC:7765]33558-1.043-0.2520No
134ME3malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985]33591-1.053-0.2416No
135CD68CD68 molecule [Source:HGNC Symbol;Acc:HGNC:1693]34116-1.231-0.2426No
136FZD9frizzled class receptor 9 [Source:HGNC Symbol;Acc:HGNC:4047]34136-1.233-0.2299No
137ANGPTL4angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]34518-1.388-0.2253No
138POU6F1POU class 6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9224]34586-1.420-0.2119No
139PIDD1p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491]35021-1.626-0.2062No
140H6PDhexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4795]35446-1.883-0.1974No
141ETV5ETS variant transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3494]35479-1.899-0.1779No
142EML3EMAP like 3 [Source:HGNC Symbol;Acc:HGNC:26666]35820-2.139-0.1642No
143DPF1double PHD fingers 1 [Source:HGNC Symbol;Acc:HGNC:20225]35978-2.279-0.1440No
144GALK1galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118]36313-2.601-0.1251No
145NFIXnuclear factor I X [Source:HGNC Symbol;Acc:HGNC:7788]36740-3.271-0.1015No
146ALOX5AParachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436]36751-3.293-0.0665No
147RND2Rho family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:18315]36794-3.383-0.0313No
148TFAP4transcription factor AP-4 [Source:HGNC Symbol;Acc:HGNC:11745]36902-3.6600.0051No
Table: GSEA details [plain text format]



Fig 2: P53_DN.V2_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: P53_DN.V2_UP: Random ES distribution   
Gene set null distribution of ES for P53_DN.V2_UP