Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5411652 |
| Normalized Enrichment Score (NES) | 1.4225115 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.059186604 |
| FWER p-Value | 0.179 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 2 | 4.966 | 0.0440 | Yes |
| 2 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 38 | 4.344 | 0.0815 | Yes |
| 3 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 44 | 4.291 | 0.1194 | Yes |
| 4 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 57 | 4.123 | 0.1557 | Yes |
| 5 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 93 | 3.728 | 0.1878 | Yes |
| 6 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 135 | 3.439 | 0.2171 | Yes |
| 7 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 238 | 2.909 | 0.2402 | Yes |
| 8 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 263 | 2.819 | 0.2645 | Yes |
| 9 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 284 | 2.731 | 0.2882 | Yes |
| 10 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 358 | 2.506 | 0.3084 | Yes |
| 11 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 469 | 2.242 | 0.3253 | Yes |
| 12 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 479 | 2.215 | 0.3447 | Yes |
| 13 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 543 | 2.084 | 0.3615 | Yes |
| 14 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 591 | 2.022 | 0.3782 | Yes |
| 15 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 623 | 1.978 | 0.3948 | Yes |
| 16 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 719 | 1.838 | 0.4086 | Yes |
| 17 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 781 | 1.763 | 0.4225 | Yes |
| 18 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 795 | 1.742 | 0.4376 | Yes |
| 19 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1197 | 1.381 | 0.4390 | Yes |
| 20 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1229 | 1.359 | 0.4502 | Yes |
| 21 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 1351 | 1.270 | 0.4582 | Yes |
| 22 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1537 | 1.161 | 0.4635 | Yes |
| 23 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1540 | 1.157 | 0.4737 | Yes |
| 24 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1643 | 1.110 | 0.4808 | Yes |
| 25 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 1865 | 1.008 | 0.4838 | Yes |
| 26 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 1987 | 0.958 | 0.4890 | Yes |
| 27 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 2014 | 0.948 | 0.4967 | Yes |
| 28 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2020 | 0.944 | 0.5049 | Yes |
| 29 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 2236 | 0.868 | 0.5068 | Yes |
| 30 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 2296 | 0.846 | 0.5127 | Yes |
| 31 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 2373 | 0.817 | 0.5179 | Yes |
| 32 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2445 | 0.795 | 0.5230 | Yes |
| 33 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 2670 | 0.725 | 0.5234 | Yes |
| 34 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 2704 | 0.721 | 0.5289 | Yes |
| 35 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 3080 | 0.621 | 0.5242 | Yes |
| 36 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 3114 | 0.610 | 0.5288 | Yes |
| 37 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 3182 | 0.591 | 0.5322 | Yes |
| 38 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 3190 | 0.589 | 0.5372 | Yes |
| 39 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3235 | 0.579 | 0.5412 | Yes |
| 40 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 3504 | 0.516 | 0.5385 | No |
| 41 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3600 | 0.495 | 0.5403 | No |
| 42 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 3820 | 0.454 | 0.5384 | No |
| 43 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 3891 | 0.441 | 0.5404 | No |
| 44 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 4172 | 0.392 | 0.5363 | No |
| 45 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4823 | 0.272 | 0.5212 | No |
| 46 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 4991 | 0.241 | 0.5188 | No |
| 47 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 5172 | 0.214 | 0.5158 | No |
| 48 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 5174 | 0.214 | 0.5177 | No |
| 49 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 5247 | 0.204 | 0.5175 | No |
| 50 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 5341 | 0.188 | 0.5167 | No |
| 51 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 5802 | 0.109 | 0.5052 | No |
| 52 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 6028 | 0.082 | 0.4998 | No |
| 53 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 6171 | 0.061 | 0.4965 | No |
| 54 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 6449 | 0.007 | 0.4891 | No |
| 55 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8958 | 0.000 | 0.4213 | No |
| 56 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9584 | 0.000 | 0.4044 | No |
| 57 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9933 | 0.000 | 0.3949 | No |
| 58 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 10124 | 0.000 | 0.3898 | No |
| 59 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10193 | 0.000 | 0.3880 | No |
| 60 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11154 | 0.000 | 0.3620 | No |
| 61 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11278 | 0.000 | 0.3587 | No |
| 62 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11319 | 0.000 | 0.3576 | No |
| 63 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11875 | 0.000 | 0.3426 | No |
| 64 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11950 | 0.000 | 0.3406 | No |
| 65 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12265 | 0.000 | 0.3321 | No |
| 66 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 12417 | 0.000 | 0.3280 | No |
| 67 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12612 | 0.000 | 0.3227 | No |
| 68 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13154 | 0.000 | 0.3081 | No |
| 69 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13963 | 0.000 | 0.2863 | No |
| 70 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16444 | 0.000 | 0.2192 | No |
| 71 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17195 | 0.000 | 0.1989 | No |
| 72 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18031 | 0.000 | 0.1763 | No |
| 73 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19300 | 0.000 | 0.1420 | No |
| 74 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 21009 | 0.000 | 0.0958 | No |
| 75 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 21257 | 0.000 | 0.0891 | No |
| 76 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22897 | 0.000 | 0.0448 | No |
| 77 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23924 | 0.000 | 0.0170 | No |
| 78 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24697 | 0.000 | -0.0039 | No |
| 79 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24904 | 0.000 | -0.0094 | No |
| 80 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 26046 | 0.000 | -0.0403 | No |
| 81 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 26829 | 0.000 | -0.0615 | No |
| 82 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 27217 | 0.000 | -0.0719 | No |
| 83 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 27736 | -0.002 | -0.0859 | No |
| 84 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 28446 | -0.116 | -0.1041 | No |
| 85 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 28553 | -0.132 | -0.1058 | No |
| 86 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 28793 | -0.162 | -0.1108 | No |
| 87 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 28800 | -0.164 | -0.1095 | No |
| 88 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 28999 | -0.184 | -0.1132 | No |
| 89 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 29352 | -0.231 | -0.1207 | No |
| 90 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 29405 | -0.236 | -0.1200 | No |
| 91 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 29498 | -0.249 | -0.1203 | No |
| 92 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 29622 | -0.268 | -0.1212 | No |
| 93 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 29669 | -0.276 | -0.1200 | No |
| 94 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 29738 | -0.286 | -0.1193 | No |
| 95 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 30164 | -0.351 | -0.1277 | No |
| 96 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 30183 | -0.354 | -0.1251 | No |
| 97 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 30818 | -0.452 | -0.1382 | No |
| 98 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 30934 | -0.470 | -0.1371 | No |
| 99 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 30965 | -0.474 | -0.1338 | No |
| 100 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 30967 | -0.474 | -0.1296 | No |
| 101 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 31031 | -0.484 | -0.1270 | No |
| 102 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 31050 | -0.488 | -0.1232 | No |
| 103 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 31513 | -0.571 | -0.1306 | No |
| 104 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 31830 | -0.631 | -0.1335 | No |
| 105 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 32286 | -0.717 | -0.1395 | No |
| 106 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 32645 | -0.810 | -0.1420 | No |
| 107 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 32824 | -0.854 | -0.1392 | No |
| 108 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 32941 | -0.890 | -0.1345 | No |
| 109 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 33020 | -0.905 | -0.1286 | No |
| 110 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 33064 | -0.916 | -0.1216 | No |
| 111 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 33599 | -1.055 | -0.1267 | No |
| 112 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 33669 | -1.081 | -0.1190 | No |
| 113 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 33810 | -1.122 | -0.1128 | No |
| 114 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 34022 | -1.198 | -0.1079 | No |
| 115 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 34313 | -1.296 | -0.1043 | No |
| 116 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34991 | -1.606 | -0.1083 | No |
| 117 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35442 | -1.881 | -0.1038 | No |
| 118 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35625 | -2.002 | -0.0910 | No |
| 119 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 36027 | -2.318 | -0.0813 | No |
| 120 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 36242 | -2.527 | -0.0647 | No |
| 121 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 36589 | -2.973 | -0.0477 | No |
| 122 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36617 | -3.023 | -0.0216 | No |
| 123 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36960 | -3.881 | 0.0035 | No |
