Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.69948506 |
| Normalized Enrichment Score (NES) | -1.4888672 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.032917432 |
| FWER p-Value | 0.116 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 16 | 4.765 | 0.0299 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 96 | 3.712 | 0.0514 | No |
| 3 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 637 | 1.958 | 0.0492 | No |
| 4 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 678 | 1.895 | 0.0602 | No |
| 5 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 705 | 1.852 | 0.0713 | No |
| 6 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 820 | 1.717 | 0.0791 | No |
| 7 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 983 | 1.543 | 0.0846 | No |
| 8 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 1007 | 1.523 | 0.0936 | No |
| 9 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 1030 | 1.507 | 0.1026 | No |
| 10 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 1634 | 1.114 | 0.0934 | No |
| 11 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 2406 | 0.808 | 0.0777 | No |
| 12 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 2658 | 0.729 | 0.0755 | No |
| 13 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 3084 | 0.619 | 0.0680 | No |
| 14 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 4814 | 0.273 | 0.0229 | No |
| 15 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 5212 | 0.209 | 0.0135 | No |
| 16 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 5375 | 0.182 | 0.0103 | No |
| 17 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 5769 | 0.112 | 0.0004 | No |
| 18 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 6290 | 0.039 | -0.0134 | No |
| 19 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6863 | 0.000 | -0.0289 | No |
| 20 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7410 | 0.000 | -0.0436 | No |
| 21 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7691 | 0.000 | -0.0512 | No |
| 22 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8450 | 0.000 | -0.0717 | No |
| 23 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9057 | 0.000 | -0.0881 | No |
| 24 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9445 | 0.000 | -0.0986 | No |
| 25 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 10059 | 0.000 | -0.1152 | No |
| 26 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 10061 | 0.000 | -0.1152 | No |
| 27 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10903 | 0.000 | -0.1379 | No |
| 28 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11710 | 0.000 | -0.1597 | No |
| 29 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12677 | 0.000 | -0.1859 | No |
| 30 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13550 | 0.000 | -0.2094 | No |
| 31 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 14032 | 0.000 | -0.2225 | No |
| 32 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14733 | 0.000 | -0.2414 | No |
| 33 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15512 | 0.000 | -0.2624 | No |
| 34 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16118 | 0.000 | -0.2788 | No |
| 35 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17128 | 0.000 | -0.3061 | No |
| 36 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19779 | 0.000 | -0.3777 | No |
| 37 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 20268 | 0.000 | -0.3909 | No |
| 38 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21979 | 0.000 | -0.4372 | No |
| 39 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 23798 | 0.000 | -0.4864 | No |
| 40 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 24343 | 0.000 | -0.5011 | No |
| 41 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 25232 | 0.000 | -0.5251 | No |
| 42 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 26139 | 0.000 | -0.5496 | No |
| 43 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 28078 | -0.065 | -0.6016 | No |
| 44 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 28412 | -0.113 | -0.6099 | No |
| 45 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 28913 | -0.179 | -0.6223 | No |
| 46 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29081 | -0.195 | -0.6256 | No |
| 47 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 29830 | -0.299 | -0.6439 | No |
| 48 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 30365 | -0.383 | -0.6559 | No |
| 49 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 30798 | -0.446 | -0.6647 | No |
| 50 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 30996 | -0.479 | -0.6670 | No |
| 51 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31026 | -0.483 | -0.6647 | No |
| 52 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 31253 | -0.523 | -0.6675 | No |
| 53 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 31293 | -0.528 | -0.6652 | No |
| 54 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 32000 | -0.670 | -0.6800 | No |
| 55 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 32389 | -0.744 | -0.6858 | No |
| 56 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 32896 | -0.875 | -0.6939 | Yes |
| 57 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 32902 | -0.875 | -0.6885 | Yes |
| 58 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 33194 | -0.950 | -0.6903 | Yes |
| 59 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 33196 | -0.951 | -0.6843 | Yes |
| 60 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 33205 | -0.952 | -0.6784 | Yes |
| 61 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 33229 | -0.958 | -0.6730 | Yes |
| 62 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33869 | -1.141 | -0.6830 | Yes |
| 63 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33917 | -1.159 | -0.6769 | Yes |
| 64 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 33942 | -1.168 | -0.6701 | Yes |
| 65 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 34093 | -1.225 | -0.6664 | Yes |
| 66 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 34134 | -1.233 | -0.6596 | Yes |
| 67 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 34166 | -1.241 | -0.6526 | Yes |
| 68 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 34264 | -1.280 | -0.6470 | Yes |
| 69 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 34288 | -1.289 | -0.6395 | Yes |
| 70 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34299 | -1.292 | -0.6315 | Yes |
| 71 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 34356 | -1.317 | -0.6247 | Yes |
| 72 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 34405 | -1.338 | -0.6174 | Yes |
| 73 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 34429 | -1.349 | -0.6095 | Yes |
| 74 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 34455 | -1.362 | -0.6015 | Yes |
| 75 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34464 | -1.368 | -0.5930 | Yes |
| 76 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 34506 | -1.383 | -0.5853 | Yes |
| 77 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 34579 | -1.416 | -0.5782 | Yes |
| 78 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34601 | -1.426 | -0.5697 | Yes |
| 79 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 34720 | -1.484 | -0.5635 | Yes |
| 80 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 34834 | -1.540 | -0.5567 | Yes |
| 81 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 34946 | -1.592 | -0.5496 | Yes |
| 82 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 35218 | -1.733 | -0.5459 | Yes |
| 83 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 35232 | -1.740 | -0.5352 | Yes |
| 84 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35387 | -1.846 | -0.5276 | Yes |
| 85 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 35515 | -1.921 | -0.5188 | Yes |
| 86 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35591 | -1.982 | -0.5083 | Yes |
| 87 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35734 | -2.079 | -0.4989 | Yes |
| 88 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35841 | -2.163 | -0.4880 | Yes |
| 89 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 35844 | -2.164 | -0.4743 | Yes |
| 90 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 35849 | -2.171 | -0.4606 | Yes |
| 91 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35888 | -2.209 | -0.4475 | Yes |
| 92 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 35901 | -2.221 | -0.4337 | Yes |
| 93 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35946 | -2.255 | -0.4206 | Yes |
| 94 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35988 | -2.283 | -0.4072 | Yes |
| 95 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36070 | -2.353 | -0.3944 | Yes |
| 96 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 36075 | -2.357 | -0.3795 | Yes |
| 97 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36085 | -2.362 | -0.3647 | Yes |
| 98 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36140 | -2.423 | -0.3508 | Yes |
| 99 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36210 | -2.489 | -0.3368 | Yes |
| 100 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36262 | -2.559 | -0.3219 | Yes |
| 101 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 36283 | -2.578 | -0.3060 | Yes |
| 102 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 36294 | -2.585 | -0.2898 | Yes |
| 103 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36337 | -2.628 | -0.2743 | Yes |
| 104 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36366 | -2.659 | -0.2581 | Yes |
| 105 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36400 | -2.699 | -0.2418 | Yes |
| 106 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36449 | -2.775 | -0.2255 | Yes |
| 107 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36558 | -2.916 | -0.2098 | Yes |
| 108 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36592 | -2.977 | -0.1918 | Yes |
| 109 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36610 | -3.004 | -0.1731 | Yes |
| 110 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36621 | -3.032 | -0.1541 | Yes |
| 111 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 36730 | -3.253 | -0.1363 | Yes |
| 112 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36775 | -3.349 | -0.1162 | Yes |
| 113 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36788 | -3.371 | -0.0951 | Yes |
| 114 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36854 | -3.536 | -0.0743 | Yes |
| 115 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36979 | -3.954 | -0.0525 | Yes |
| 116 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 37042 | -4.336 | -0.0266 | Yes |
| 117 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 37051 | -4.386 | 0.0011 | Yes |
