Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7519443 |
| Normalized Enrichment Score (NES) | -1.6309817 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024088854 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 138 | 3.425 | 0.0172 | No |
| 2 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 246 | 2.874 | 0.0319 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 330 | 2.590 | 0.0455 | No |
| 4 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1075 | 1.468 | 0.0343 | No |
| 5 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1117 | 1.440 | 0.0420 | No |
| 6 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 1512 | 1.171 | 0.0385 | No |
| 7 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 2048 | 0.933 | 0.0298 | No |
| 8 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 2222 | 0.871 | 0.0304 | No |
| 9 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 4237 | 0.380 | -0.0218 | No |
| 10 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 4904 | 0.256 | -0.0382 | No |
| 11 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 5319 | 0.192 | -0.0482 | No |
| 12 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 5449 | 0.169 | -0.0507 | No |
| 13 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 6095 | 0.071 | -0.0677 | No |
| 14 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 6158 | 0.062 | -0.0690 | No |
| 15 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 6290 | 0.039 | -0.0723 | No |
| 16 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 6432 | 0.012 | -0.0761 | No |
| 17 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 6505 | 0.006 | -0.0780 | No |
| 18 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6927 | 0.000 | -0.0894 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8322 | 0.000 | -0.1271 | No |
| 20 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9649 | 0.000 | -0.1629 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9859 | 0.000 | -0.1686 | No |
| 22 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10741 | 0.000 | -0.1924 | No |
| 23 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11464 | 0.000 | -0.2120 | No |
| 24 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12217 | 0.000 | -0.2323 | No |
| 25 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12571 | 0.000 | -0.2419 | No |
| 26 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12717 | 0.000 | -0.2458 | No |
| 27 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12760 | 0.000 | -0.2469 | No |
| 28 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13028 | 0.000 | -0.2542 | No |
| 29 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 13029 | 0.000 | -0.2542 | No |
| 30 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13620 | 0.000 | -0.2701 | No |
| 31 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 13939 | 0.000 | -0.2787 | No |
| 32 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14881 | 0.000 | -0.3042 | No |
| 33 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15636 | 0.000 | -0.3246 | No |
| 34 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16118 | 0.000 | -0.3376 | No |
| 35 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16346 | 0.000 | -0.3437 | No |
| 36 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16417 | 0.000 | -0.3456 | No |
| 37 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16558 | 0.000 | -0.3494 | No |
| 38 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16654 | 0.000 | -0.3520 | No |
| 39 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17573 | 0.000 | -0.3768 | No |
| 40 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18757 | 0.000 | -0.4088 | No |
| 41 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18758 | 0.000 | -0.4088 | No |
| 42 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 19018 | 0.000 | -0.4158 | No |
| 43 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19687 | 0.000 | -0.4339 | No |
| 44 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19826 | 0.000 | -0.4376 | No |
| 45 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20389 | 0.000 | -0.4528 | No |
| 46 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21207 | 0.000 | -0.4750 | No |
| 47 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21445 | 0.000 | -0.4814 | No |
| 48 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21979 | 0.000 | -0.4958 | No |
| 49 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24503 | 0.000 | -0.5640 | No |
| 50 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 24806 | 0.000 | -0.5722 | No |
| 51 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25909 | 0.000 | -0.6020 | No |
| 52 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 27913 | -0.037 | -0.6560 | No |
| 53 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 28490 | -0.122 | -0.6708 | No |
| 54 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 28734 | -0.154 | -0.6765 | No |
| 55 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 28860 | -0.173 | -0.6788 | No |
| 56 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 28904 | -0.178 | -0.6789 | No |
| 57 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 29081 | -0.195 | -0.6824 | No |
| 58 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 29167 | -0.208 | -0.6835 | No |
| 59 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 29507 | -0.250 | -0.6911 | No |
| 60 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29779 | -0.292 | -0.6967 | No |
| 61 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30428 | -0.392 | -0.7118 | No |
| 62 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 30716 | -0.435 | -0.7169 | No |
| 63 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 31340 | -0.538 | -0.7305 | No |
| 64 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 31627 | -0.592 | -0.7346 | No |
| 65 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 31637 | -0.594 | -0.7312 | No |
| 66 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 31936 | -0.656 | -0.7352 | No |
| 67 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 32235 | -0.704 | -0.7390 | No |
| 68 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 32462 | -0.763 | -0.7405 | No |
| 69 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 32540 | -0.779 | -0.7378 | No |
| 70 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 32561 | -0.787 | -0.7335 | No |
| 71 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 32937 | -0.889 | -0.7382 | No |
| 72 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 32968 | -0.896 | -0.7335 | No |
| 73 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33273 | -0.969 | -0.7358 | No |
| 74 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33869 | -1.141 | -0.7450 | Yes |
| 75 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 33944 | -1.168 | -0.7398 | Yes |
| 76 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 34129 | -1.233 | -0.7373 | Yes |
| 77 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34299 | -1.292 | -0.7339 | Yes |
| 78 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34334 | -1.307 | -0.7269 | Yes |
| 79 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34464 | -1.368 | -0.7220 | Yes |
| 80 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34611 | -1.432 | -0.7172 | Yes |
| 81 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34695 | -1.475 | -0.7104 | Yes |
| 82 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34741 | -1.496 | -0.7025 | Yes |
| 83 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 34908 | -1.576 | -0.6973 | Yes |
| 84 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 34934 | -1.589 | -0.6883 | Yes |
| 85 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 34946 | -1.592 | -0.6789 | Yes |
| 86 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 35021 | -1.626 | -0.6709 | Yes |
| 87 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35131 | -1.687 | -0.6636 | Yes |
| 88 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35249 | -1.754 | -0.6560 | Yes |
| 89 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 35255 | -1.762 | -0.6454 | Yes |
| 90 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35387 | -1.846 | -0.6376 | Yes |
| 91 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35394 | -1.848 | -0.6265 | Yes |
| 92 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 35465 | -1.891 | -0.6168 | Yes |
| 93 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35466 | -1.893 | -0.6052 | Yes |
| 94 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35492 | -1.906 | -0.5943 | Yes |
| 95 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35734 | -2.079 | -0.5881 | Yes |
| 96 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35735 | -2.080 | -0.5753 | Yes |
| 97 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35739 | -2.082 | -0.5627 | Yes |
| 98 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35798 | -2.127 | -0.5513 | Yes |
| 99 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35813 | -2.135 | -0.5386 | Yes |
| 100 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 35816 | -2.138 | -0.5256 | Yes |
| 101 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35841 | -2.163 | -0.5130 | Yes |
| 102 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36014 | -2.309 | -0.5035 | Yes |
| 103 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 36043 | -2.325 | -0.4901 | Yes |
| 104 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36085 | -2.362 | -0.4767 | Yes |
| 105 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36140 | -2.423 | -0.4634 | Yes |
| 106 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36168 | -2.442 | -0.4492 | Yes |
| 107 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36262 | -2.559 | -0.4360 | Yes |
| 108 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36284 | -2.578 | -0.4208 | Yes |
| 109 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36297 | -2.588 | -0.4053 | Yes |
| 110 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36315 | -2.604 | -0.3899 | Yes |
| 111 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36337 | -2.628 | -0.3744 | Yes |
| 112 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36366 | -2.659 | -0.3589 | Yes |
| 113 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36454 | -2.785 | -0.3442 | Yes |
| 114 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36463 | -2.797 | -0.3273 | Yes |
| 115 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36478 | -2.807 | -0.3105 | Yes |
| 116 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36535 | -2.886 | -0.2944 | Yes |
| 117 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36621 | -3.032 | -0.2782 | Yes |
| 118 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36682 | -3.139 | -0.2606 | Yes |
| 119 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36746 | -3.284 | -0.2422 | Yes |
| 120 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36774 | -3.348 | -0.2225 | Yes |
| 121 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36788 | -3.371 | -0.2022 | Yes |
| 122 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36817 | -3.427 | -0.1820 | Yes |
| 123 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36844 | -3.516 | -0.1612 | Yes |
| 124 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36875 | -3.599 | -0.1400 | Yes |
| 125 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36879 | -3.606 | -0.1181 | Yes |
| 126 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36962 | -3.887 | -0.0965 | Yes |
| 127 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 36975 | -3.942 | -0.0727 | Yes |
| 128 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36979 | -3.954 | -0.0486 | Yes |
| 129 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36995 | -4.056 | -0.0242 | Yes |
| 130 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 37050 | -4.379 | 0.0011 | Yes |
