Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_GAQ
GeneSetRELA_DN.V1_UP
Enrichment Score (ES)0.45015946
Normalized Enrichment Score (NES)1.2051045
Nominal p-value0.019607844
FDR q-value0.17633516
FWER p-Value0.717
Table: GSEA Results Summary



Fig 1: Enrichment plot: RELA_DN.V1_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IL1Binterleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992]14.9870.0386Yes
2TNCtenascin C [Source:HGNC Symbol;Acc:HGNC:5318]24.9660.0770Yes
3PTGS2prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]44.9390.1152Yes
4FOSL1FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718]134.7950.1521Yes
5GADD45Bgrowth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096]234.6070.1875Yes
6ZFP36ZFP36 ring finger protein [Source:HGNC Symbol;Acc:HGNC:12862]314.4030.2213Yes
7JUNBJunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205]1283.4950.2458Yes
8GRAPGRB2 related adaptor protein [Source:HGNC Symbol;Acc:HGNC:4562]1943.1420.2683Yes
9FOSBFosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797]2103.0570.2916Yes
10F9coagulation factor IX [Source:HGNC Symbol;Acc:HGNC:3551]2272.9730.3141Yes
11EGR3early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240]4672.2450.3250Yes
12SAMSN1SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528]7001.8600.3331Yes
13ATF3activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785]7041.8530.3474Yes
14SLC7A1solute carrier family 7 member 1 [Source:HGNC Symbol;Acc:HGNC:11057]7241.8310.3611Yes
15AGPAT41-acylglycerol-3-phosphate O-acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:20885]7451.7990.3744Yes
16RNF25ring finger protein 25 [Source:HGNC Symbol;Acc:HGNC:14662]10121.5190.3790Yes
17TANKTRAF family member associated NFKB activator [Source:HGNC Symbol;Acc:HGNC:11562]10471.4910.3896Yes
18ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811]11161.4410.3989Yes
19BPNT13'(2'), 5'-bisphosphate nucleotidase 1 [Source:HGNC Symbol;Acc:HGNC:1096]11601.4130.4087Yes
20PAFAH1B2platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:8575]12391.3520.4170Yes
21FOSFos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796]12461.3430.4273Yes
22EGR1early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238]13961.2440.4328Yes
23TREX1three prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:12269]13981.2420.4424Yes
24MYBPC3myosin binding protein C3 [Source:HGNC Symbol;Acc:HGNC:7551]14581.2060.4502Yes
25PPP1R15Aprotein phosphatase 1 regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375]23930.8110.4312No
26GPR85G protein-coupled receptor 85 [Source:HGNC Symbol;Acc:HGNC:4536]24210.8020.4366No
27INTS6integrator complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:14879]24910.7800.4408No
28NLKnemo like kinase [Source:HGNC Symbol;Acc:HGNC:29858]26110.7450.4433No
29KLF6Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235]32830.5680.4296No
30RIPK1receptor interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:10019]36100.4930.4246No
31DUSP8dual specificity phosphatase 8 [Source:HGNC Symbol;Acc:HGNC:3074]36660.4850.4268No
32RREB1ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]38350.4510.4258No
33JUNJun proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6204]41280.3990.4209No
34VDRvitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679]42590.3760.4203No
35FGF17fibroblast growth factor 17 [Source:HGNC Symbol;Acc:HGNC:3673]43930.3480.4194No
36ZNF222zinc finger protein 222 [Source:HGNC Symbol;Acc:HGNC:13015]45570.3220.4175No
37MC3Rmelanocortin 3 receptor [Source:HGNC Symbol;Acc:HGNC:6931]47690.2800.4140No
38ZFP37ZFP37 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:12863]51820.2130.4045No
39USP9Yubiquitin specific peptidase 9 Y-linked [Source:HGNC Symbol;Acc:HGNC:12633]53080.1940.4026No
40ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]59360.0970.3863No
41KDM5Dlysine demethylase 5D [Source:HGNC Symbol;Acc:HGNC:11115]60190.0830.3848No
42FGF2fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676]62660.0440.3784No
43AP4E1adaptor related protein complex 4 subunit epsilon 1 [Source:HGNC Symbol;Acc:HGNC:573]63900.0220.3753No
44LAMC2laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493]64490.0070.3738No
45LHCGRluteinizing hormone/choriogonadotropin receptor [Source:HGNC Symbol;Acc:HGNC:6585]66440.0000.3685No
46SCG5secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816]67520.0000.3656No
47FXYD7FXYD domain containing ion transport regulator 7 [Source:HGNC Symbol;Acc:HGNC:4034]68610.0000.3627No
48APOBapolipoprotein B [Source:HGNC Symbol;Acc:HGNC:603]70470.0000.3577No
49PRDM11PR/SET domain 11 [Source:HGNC Symbol;Acc:HGNC:13996]71600.0000.3547No
50PRKG1protein kinase cGMP-dependent 1 [Source:HGNC Symbol;Acc:HGNC:9414]72510.0000.3522No
51DEPP1DEPP1 autophagy regulator [Source:HGNC Symbol;Acc:HGNC:23355]83100.0000.3236No
52TNFRSF9TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924]99930.0000.2780No
53CELPcarboxyl ester lipase pseudogene [Source:HGNC Symbol;Acc:HGNC:1849]99980.0000.2779No
54KCNQ4potassium voltage-gated channel subfamily Q member 4 [Source:HGNC Symbol;Acc:HGNC:6298]100530.0000.2765No
55DNMT3LDNA methyltransferase 3 like [Source:HGNC Symbol;Acc:HGNC:2980]108650.0000.2545No
56SLC27A6solute carrier family 27 member 6 [Source:HGNC Symbol;Acc:HGNC:11000]110990.0000.2482No
57MS4A3membrane spanning 4-domains A3 [Source:HGNC Symbol;Acc:HGNC:7317]112460.0000.2443No
58SLC6A14solute carrier family 6 member 14 [Source:HGNC Symbol;Acc:HGNC:11047]120110.0000.2236No
59ESM1endothelial cell specific molecule 1 [Source:HGNC Symbol;Acc:HGNC:3466]120600.0000.2223No
60PODXL2podocalyxin like 2 [Source:HGNC Symbol;Acc:HGNC:17936]124740.0000.2111No
61DYSFdysferlin [Source:HGNC Symbol;Acc:HGNC:3097]125360.0000.2095No
62CDKN2Bcyclin dependent kinase inhibitor 2B [Source:HGNC Symbol;Acc:HGNC:1788]127860.0000.2027No
63LILRP2leukocyte immunoglobulin-like receptor pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:15497]131270.0000.1935No
64TLX1T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056]144480.0000.1578No
65INE1inactivation escape 1 [Source:HGNC Symbol;Acc:HGNC:6060]149250.0000.1449No
66GHRHgrowth hormone releasing hormone [Source:HGNC Symbol;Acc:HGNC:4265]152460.0000.1362No
67ULBP2UL16 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14894]152750.0000.1355No
68TRIM38tripartite motif containing 38 [Source:HGNC Symbol;Acc:HGNC:10059]154570.0000.1306No
69GLYATglycine-N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:13734]155610.0000.1278No
70HTR1F5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292]156880.0000.1244No
71XCL1X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645]159580.0000.1171No
72F3coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541]162410.0000.1095No
73RNF39ring finger protein 39 [Source:HGNC Symbol;Acc:HGNC:18064]166210.0000.0992No
74MAKmale germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]189280.0000.0368No
75CDHR5cadherin related family member 5 [Source:HGNC Symbol;Acc:HGNC:7521]191490.0000.0308No
76NTSneurotensin [Source:HGNC Symbol;Acc:HGNC:8038]194540.0000.0226No
77FLRT1fibronectin leucine rich transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3760]199260.0000.0098No
78PIPprolactin induced protein [Source:HGNC Symbol;Acc:HGNC:8993]200390.0000.0068No
79GJB1gap junction protein beta 1 [Source:HGNC Symbol;Acc:HGNC:4283]210100.000-0.0194No
80P2RY11purinergic receptor P2Y11 [Source:HGNC Symbol;Acc:HGNC:8540]214560.000-0.0315No
81CCL2C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618]230490.000-0.0746No
82CD38CD38 molecule [Source:HGNC Symbol;Acc:HGNC:1667]231390.000-0.0770No
83ZNF165zinc finger protein 165 [Source:HGNC Symbol;Acc:HGNC:12953]232720.000-0.0806No
84MEP1Bmeprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020]234280.000-0.0848No
85NOL4nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870]234990.000-0.0867No
86DEFB1defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766]236510.000-0.0907No
87PNLIPRP1pancreatic lipase related protein 1 [Source:HGNC Symbol;Acc:HGNC:9156]238920.000-0.0972No
88KCNJ16potassium inwardly rectifying channel subfamily J member 16 [Source:HGNC Symbol;Acc:HGNC:6262]240680.000-0.1020No
89CDK5R2cyclin dependent kinase 5 regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:1776]241180.000-0.1033No
90DLGAP1DLG associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2905]242570.000-0.1070No
91CRB1crumbs cell polarity complex component 1 [Source:HGNC Symbol;Acc:HGNC:2343]242770.000-0.1076No
92HOOK1hook microtubule tethering protein 1 [Source:HGNC Symbol;Acc:HGNC:19884]245420.000-0.1147No
93CLDN15claudin 15 [Source:HGNC Symbol;Acc:HGNC:2036]248940.000-0.1242No
94CST5cystatin D [Source:HGNC Symbol;Acc:HGNC:2477]249080.000-0.1246No
95FHL5four and a half LIM domains 5 [Source:HGNC Symbol;Acc:HGNC:17371]260490.000-0.1554No
96MAGEB4MAGE family member B4 [Source:HGNC Symbol;Acc:HGNC:6811]269290.000-0.1792No
97DGKIdiacylglycerol kinase iota [Source:HGNC Symbol;Acc:HGNC:2855]274370.000-0.1929No
98CLK1CDC like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2068]27798-0.015-0.2026No
99SNAPC1small nuclear RNA activating complex polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:11134]27862-0.028-0.2041No
100KCNA1potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218]27913-0.037-0.2051No
101SIRT4sirtuin 4 [Source:HGNC Symbol;Acc:HGNC:14932]27920-0.038-0.2050No
102THBDthrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784]28107-0.070-0.2095No
103CYP26B1cytochrome P450 family 26 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:20581]28418-0.114-0.2170No
104ATP8A2ATPase phospholipid transporting 8A2 [Source:HGNC Symbol;Acc:HGNC:13533]28498-0.123-0.2182No
105CRYGAcrystallin gamma A [Source:HGNC Symbol;Acc:HGNC:2408]28582-0.135-0.2194No
106GAD1glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092]28632-0.140-0.2196No
107BCO1beta-carotene oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:13815]28672-0.145-0.2196No
108SNAI1snail family transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:11128]28763-0.158-0.2208No
109CTF1cardiotrophin 1 [Source:HGNC Symbol;Acc:HGNC:2499]28775-0.160-0.2198No
110PPANpeter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227]28841-0.172-0.2203No
111PGGT1Bprotein geranylgeranyltransferase type I subunit beta [Source:HGNC Symbol;Acc:HGNC:8895]28843-0.172-0.2190No
112WASLWASP like actin nucleation promoting factor [Source:HGNC Symbol;Acc:HGNC:12735]28869-0.174-0.2183No
113P2RY10P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906]29014-0.187-0.2207No
114TEX14testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737]29397-0.236-0.2293No
115VEGFAvascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680]29736-0.285-0.2362No
116ZNF324zinc finger protein 324 [Source:HGNC Symbol;Acc:HGNC:14096]29754-0.288-0.2344No
117KMOkynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381]29882-0.307-0.2355No
118APBA2amyloid beta precursor protein binding family A member 2 [Source:HGNC Symbol;Acc:HGNC:579]30258-0.366-0.2428No
119ZNHIT2zinc finger HIT-type containing 2 [Source:HGNC Symbol;Acc:HGNC:1177]30520-0.404-0.2468No
120ZNF286Azinc finger protein 286A [Source:HGNC Symbol;Acc:HGNC:13501]30690-0.430-0.2480No
121PDE5Aphosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]30962-0.474-0.2517No
122SRCAPSnf2 related CREBBP activator protein [Source:HGNC Symbol;Acc:HGNC:16974]31020-0.483-0.2495No
123LMO7LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:6646]31353-0.541-0.2543No
124WRNIP1WRN helicase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20876]31491-0.567-0.2536No
125TPMTthiopurine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:12014]31510-0.571-0.2497No
126PEX6peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859]31728-0.613-0.2508No
127GPTglutamic--pyruvic transaminase [Source:HGNC Symbol;Acc:HGNC:4552]32116-0.692-0.2559No
128KMT2Dlysine methyltransferase 2D [Source:HGNC Symbol;Acc:HGNC:7133]32718-0.828-0.2658No
129ETFDHelectron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]33518-1.030-0.2795No
130SIRPB1signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928]33789-1.117-0.2781No
131GNRH1gonadotropin releasing hormone 1 [Source:HGNC Symbol;Acc:HGNC:4419]34005-1.189-0.2747No
132FZD9frizzled class receptor 9 [Source:HGNC Symbol;Acc:HGNC:4047]34136-1.233-0.2687No
133BIN1bridging integrator 1 [Source:HGNC Symbol;Acc:HGNC:1052]34230-1.266-0.2614No
134ATP5F1CATP synthase F1 subunit gamma [Source:HGNC Symbol;Acc:HGNC:833]34486-1.375-0.2577No
135MTMR11myotubularin related protein 11 [Source:HGNC Symbol;Acc:HGNC:24307]34775-1.512-0.2538No
136DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides 1 [Source:HGNC Symbol;Acc:HGNC:16500]35044-1.640-0.2484No
137KCNC4potassium voltage-gated channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:6236]35334-1.813-0.2422No
138NFICnuclear factor I C [Source:HGNC Symbol;Acc:HGNC:7786]35437-1.879-0.2304No
139GLS2glutaminase 2 [Source:HGNC Symbol;Acc:HGNC:29570]35450-1.885-0.2161No
140LGMNlegumain [Source:HGNC Symbol;Acc:HGNC:9472]35838-2.162-0.2099No
141ZFP36L1ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]36236-2.523-0.2011No
142GAS7growth arrest specific 7 [Source:HGNC Symbol;Acc:HGNC:4169]36432-2.737-0.1852No
143NOVA1NOVA alternative splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:7886]36484-2.826-0.1647No
144EFNA1ephrin A1 [Source:HGNC Symbol;Acc:HGNC:3221]36706-3.184-0.1461No
145KLF10Kruppel like factor 10 [Source:HGNC Symbol;Acc:HGNC:11810]36919-3.696-0.1232No
146PDK1pyruvate dehydrogenase kinase 1 [Source:HGNC Symbol;Acc:HGNC:8809]36948-3.808-0.0945No
147VEGFBvascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681]36975-3.942-0.0647No
148GPR183G protein-coupled receptor 183 [Source:HGNC Symbol;Acc:HGNC:3128]37045-4.344-0.0330No
149CHST1carbohydrate sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:1969]37054-4.4190.0010No
Table: GSEA details [plain text format]



Fig 2: RELA_DN.V1_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: RELA_DN.V1_UP: Random ES distribution   
Gene set null distribution of ES for RELA_DN.V1_UP