Datasetgreenberg_collapsed_to_symbols.Nof1.cls
#WT_GAQ_versus_WT_NA.Nof1.cls
#WT_GAQ_versus_WT_NA_repos
PhenotypeNof1.cls#WT_GAQ_versus_WT_NA_repos
Upregulated in classWT_NA
GeneSetSRC_UP.V1_DN
Enrichment Score (ES)-0.57653373
Normalized Enrichment Score (NES)-1.2671562
Nominal p-value0.02494577
FDR q-value0.3210067
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: SRC_UP.V1_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SERPINB2serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584]1103.6230.0274No
2IFIT1interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407]1483.3350.0543No
3POP1POP1 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30129]3492.5290.0701No
4ACSL4acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]4422.3060.0869No
5COP1COP1 E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:17440]9041.6190.0880No
6DTWD1DTW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30926]10321.5040.0971No
7STARD3StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579]10511.4850.1091No
8ZNF436zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814]11551.4140.1181No
9RRN3RRN3 homolog, RNA polymerase I transcription factor [Source:HGNC Symbol;Acc:HGNC:30346]13871.2480.1224No
10RAB33BRAB33B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16075]18940.9960.1170No
11POLR1ARNA polymerase I subunit A [Source:HGNC Symbol;Acc:HGNC:17264]21770.8840.1168No
12ZNF3zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]26410.7360.1104No
13STK17Bserine/threonine kinase 17b [Source:HGNC Symbol;Acc:HGNC:11396]26830.7220.1153No
14CENPScentromere protein S [Source:HGNC Symbol;Acc:HGNC:23163]27560.7070.1193No
15CA7carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:1381]33800.5480.1070No
16EIF3CLeukaryotic translation initiation factor 3 subunit C like [Source:HGNC Symbol;Acc:HGNC:26347]38700.4450.0975No
17PPIL1peptidylprolyl isomerase like 1 [Source:HGNC Symbol;Acc:HGNC:9260]40890.4070.0950No
18FANCLFA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748]42370.3800.0942No
19ZNF451zinc finger protein 451 [Source:HGNC Symbol;Acc:HGNC:21091]42820.3700.0961No
20MYSM1Myb like, SWIRM and MPN domains 1 [Source:HGNC Symbol;Acc:HGNC:29401]47960.2760.0845No
21CMTR2cap methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:25635]50070.2400.0809No
22PTGER4prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596]51890.2120.0777No
23NOL12nucleolar protein 12 [Source:HGNC Symbol;Acc:HGNC:28585]53120.1930.0760No
24COMMD9COMM domain containing 9 [Source:HGNC Symbol;Acc:HGNC:25014]54110.1760.0749No
25RTN4IP1reticulon 4 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18647]54550.1680.0751No
26MMP10matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156]55210.1550.0746No
27HS3ST3A1heparan sulfate-glucosamine 3-sulfotransferase 3A1 [Source:HGNC Symbol;Acc:HGNC:5196]55740.1460.0744No
28SEMA6Bsemaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739]56250.1380.0742No
29CSADcysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966]57080.1230.0731No
30CDK11Bcyclin dependent kinase 11B [Source:HGNC Symbol;Acc:HGNC:1729]59910.0870.0662No
31TMEM14Atransmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076]64950.0070.0526No
32C11orf72chromosome 11 putative open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:26915]65850.0000.0502No
33PRSS33serine protease 33 [Source:HGNC Symbol;Acc:HGNC:30405]66120.0000.0495No
34CWH43cell wall biogenesis 43 C-terminal homolog [Source:HGNC Symbol;Acc:HGNC:26133]71430.0000.0351No
35DGCR11DiGeorge syndrome critical region gene 11 [Source:HGNC Symbol;Acc:HGNC:17226]72540.0000.0321No
36ARSJarylsulfatase family member J [Source:HGNC Symbol;Acc:HGNC:26286]76760.0000.0207No
37DEPP1DEPP1 autophagy regulator [Source:HGNC Symbol;Acc:HGNC:23355]83100.0000.0036No
38WT1-ASWT1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:18135]83570.0000.0023No
39S100A9S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499]87540.000-0.0084No
40PRR19proline rich 19 [Source:HGNC Symbol;Acc:HGNC:33728]90190.000-0.0155No
41NPY5Rneuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958]93210.000-0.0237No
42GRID1glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575]94440.000-0.0270No
43ZNF135zinc finger protein 135 [Source:HGNC Symbol;Acc:HGNC:12919]95780.000-0.0306No
44PLATplasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051]101110.000-0.0450No
45SPRR1Bsmall proline rich protein 1B [Source:HGNC Symbol;Acc:HGNC:11260]103860.000-0.0524No
46MEGF6multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]104070.000-0.0530No
47ADH4alcohol dehydrogenase 4 (class II), pi polypeptide [Source:HGNC Symbol;Acc:HGNC:252]113010.000-0.0771No
48GFRA3GDNF family receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4245]114150.000-0.0802No
49EREGepiregulin [Source:HGNC Symbol;Acc:HGNC:3443]116820.000-0.0874No
50C17orf64chromosome 17 open reading frame 64 [Source:HGNC Symbol;Acc:HGNC:26990]119260.000-0.0940No
51LYPD3LY6/PLAUR domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24880]122200.000-0.1019No
52SPDYE1speedy/RINGO cell cycle regulator family member E1 [Source:HGNC Symbol;Acc:HGNC:16408]125430.000-0.1106No
53TGM5transglutaminase 5 [Source:HGNC Symbol;Acc:HGNC:11781]126640.000-0.1139No
54ZBED2zinc finger BED-type containing 2 [Source:HGNC Symbol;Acc:HGNC:20710]132330.000-0.1293No
55SYT15synaptotagmin 15 [Source:HGNC Symbol;Acc:HGNC:17167]138290.000-0.1454No
56NYNRINNYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165]140860.000-0.1523No
57PIK3C2Gphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [Source:HGNC Symbol;Acc:HGNC:8973]142180.000-0.1559No
58PIK3C2Bphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [Source:HGNC Symbol;Acc:HGNC:8972]142200.000-0.1559No
59PCDH19protocadherin 19 [Source:HGNC Symbol;Acc:HGNC:14270]147370.000-0.1699No
60TRIM73tripartite motif containing 73 [Source:HGNC Symbol;Acc:HGNC:18162]154120.000-0.1881No
61C8Bcomplement C8 beta chain [Source:HGNC Symbol;Acc:HGNC:1353]157700.000-0.1978No
62SLC7A14solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326]163510.000-0.2135No
63EMBembigin [Source:HGNC Symbol;Acc:HGNC:30465]164880.000-0.2172No
64SYT1synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509]170690.000-0.2329No
65IVLinvolucrin [Source:HGNC Symbol;Acc:HGNC:6187]178600.000-0.2543No
66GTF2H2general transcription factor IIH subunit 2 [Source:HGNC Symbol;Acc:HGNC:4656]178720.000-0.2546No
67S1PR3sphingosine-1-phosphate receptor 3 [Source:HGNC Symbol;Acc:HGNC:3167]180300.000-0.2588No
68DPYDdihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012]181710.000-0.2626No
69MMP1matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155]191330.000-0.2887No
70MMP3matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173]191370.000-0.2887No
71COL8A1collagen type VIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2215]193360.000-0.2941No
72SPNS3sphingolipid transporter 3 (putative) [Source:HGNC Symbol;Acc:HGNC:28433]194310.000-0.2967No
73CXCL5C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642]194900.000-0.2982No
74UTS2Rurotensin 2 receptor [Source:HGNC Symbol;Acc:HGNC:4468]206890.000-0.3307No
75IFI6interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054]207320.000-0.3318No
76GJB6gap junction protein beta 6 [Source:HGNC Symbol;Acc:HGNC:4288]210130.000-0.3394No
77ZNF789zinc finger protein 789 [Source:HGNC Symbol;Acc:HGNC:27801]210550.000-0.3405No
78ZNF782zinc finger protein 782 [Source:HGNC Symbol;Acc:HGNC:33110]210580.000-0.3406No
79ZNF721zinc finger protein 721 [Source:HGNC Symbol;Acc:HGNC:29425]215620.000-0.3542No
80IRGCimmunity related GTPase cinema [Source:HGNC Symbol;Acc:HGNC:28835]218020.000-0.3607No
81PHLDA2pleckstrin homology like domain family A member 2 [Source:HGNC Symbol;Acc:HGNC:12385]219160.000-0.3637No
82LINC00842long intergenic non-protein coding RNA 842 [Source:HGNC Symbol;Acc:HGNC:44989]233490.000-0.4025No
83COBLcordon-bleu WH2 repeat protein [Source:HGNC Symbol;Acc:HGNC:22199]234230.000-0.4045No
84ADGRF1adhesion G protein-coupled receptor F1 [Source:HGNC Symbol;Acc:HGNC:18990]245780.000-0.4357No
85FAM153Afamily with sequence similarity 153 member A [Source:HGNC Symbol;Acc:HGNC:29940]245840.000-0.4359No
86CLCA4chloride channel accessory 4 [Source:HGNC Symbol;Acc:HGNC:2018]247630.000-0.4407No
87KCNMB3potassium calcium-activated channel subfamily M regulatory beta subunit 3 [Source:HGNC Symbol;Acc:HGNC:6287]250690.000-0.4489No
88TMCO2transmembrane and coiled-coil domains 2 [Source:HGNC Symbol;Acc:HGNC:23312]251170.000-0.4502No
89ANHXanomalous homeobox [Source:HGNC Symbol;Acc:HGNC:40024]252090.000-0.4527No
90IFITM10interferon induced transmembrane protein 10 [Source:HGNC Symbol;Acc:HGNC:40022]252390.000-0.4535No
91ATPSCKMTATP synthase c subunit lysine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:27029]269450.000-0.4996No
92NLRP8NLR family pyrin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:22940]270000.000-0.5011No
93ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870]272170.000-0.5070No
94DISP2dispatched RND transporter family member 2 [Source:HGNC Symbol;Acc:HGNC:19712]27842-0.024-0.5237No
95IL7Rinterleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024]27994-0.049-0.5273No
96COQ4coenzyme Q4 [Source:HGNC Symbol;Acc:HGNC:19693]28013-0.054-0.5274No
97ADGRE1adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336]28078-0.065-0.5286No
98RARAretinoic acid receptor alpha [Source:HGNC Symbol;Acc:HGNC:9864]28257-0.090-0.5326No
99SH3TC2SH3 domain and tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:29427]28267-0.092-0.5321No
100PAK3p21 (RAC1) activated kinase 3 [Source:HGNC Symbol;Acc:HGNC:8592]28423-0.114-0.5354No
101OTUD6BOTU deubiquitinase 6B [Source:HGNC Symbol;Acc:HGNC:24281]28480-0.121-0.5359No
102MIR17HGmiR-17-92a-1 cluster host gene [Source:HGNC Symbol;Acc:HGNC:23564]28993-0.184-0.5482No
103GON7GON7 subunit of KEOPS complex [Source:HGNC Symbol;Acc:HGNC:20356]29055-0.191-0.5482No
104ZNF628zinc finger protein 628 [Source:HGNC Symbol;Acc:HGNC:28054]29245-0.220-0.5515No
105KIAA1841KIAA1841 [Source:HGNC Symbol;Acc:HGNC:29387]29450-0.243-0.5550No
106MON1AMON1 homolog A, secretory trafficking associated [Source:HGNC Symbol;Acc:HGNC:28207]29478-0.247-0.5537No
107HOXB2homeobox B2 [Source:HGNC Symbol;Acc:HGNC:5113]29482-0.248-0.5517No
108MGARPmitochondria localized glutamic acid rich protein [Source:HGNC Symbol;Acc:HGNC:29969]29615-0.267-0.5530No
109CAPN12calpain 12 [Source:HGNC Symbol;Acc:HGNC:13249]29645-0.271-0.5515No
110CTDP1CTD phosphatase subunit 1 [Source:HGNC Symbol;Acc:HGNC:2498]29650-0.272-0.5494No
111PCDHB4protocadherin beta 4 [Source:HGNC Symbol;Acc:HGNC:8689]29829-0.299-0.5517No
112IRAK2interleukin 1 receptor associated kinase 2 [Source:HGNC Symbol;Acc:HGNC:6113]29832-0.299-0.5492No
113GALNTL6polypeptide N-acetylgalactosaminyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:33844]30154-0.350-0.5550No
114NFKBIENFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799]30195-0.355-0.5531No
115ANO7anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677]30404-0.390-0.5555No
116ABHD3abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718]30999-0.480-0.5675No
117TREML1triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434]31275-0.526-0.5706No
118CENPHcentromere protein H [Source:HGNC Symbol;Acc:HGNC:17268]31340-0.538-0.5678No
119MN1MN1 proto-oncogene, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:7180]31389-0.547-0.5645No
120PLK4polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397]31450-0.559-0.5615No
121SLC12A5solute carrier family 12 member 5 [Source:HGNC Symbol;Acc:HGNC:13818]31603-0.587-0.5607No
122ACTL6Aactin like 6A [Source:HGNC Symbol;Acc:HGNC:24124]32190-0.698-0.5707Yes
123PTBP2polypyrimidine tract binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17662]32304-0.721-0.5677Yes
124GDPD3glycerophosphodiester phosphodiesterase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28638]32376-0.740-0.5634Yes
125CARNMT1carnosine N-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23435]32651-0.811-0.5641Yes
126SLC2A6solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011]32918-0.880-0.5639Yes
127IRX5iroquois homeobox 5 [Source:HGNC Symbol;Acc:HGNC:14361]32953-0.894-0.5573Yes
128RNF168ring finger protein 168 [Source:HGNC Symbol;Acc:HGNC:26661]32977-0.898-0.5504Yes
129CERKLceramide kinase like [Source:HGNC Symbol;Acc:HGNC:21699]32984-0.899-0.5430Yes
130WASH3PWASP family homolog 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:24362]33046-0.912-0.5371Yes
131ARRDC3arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263]33170-0.946-0.5325Yes
132RAP1ARAP1A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9855]33393-1.003-0.5301Yes
133SNX32sorting nexin 32 [Source:HGNC Symbol;Acc:HGNC:26423]33395-1.004-0.5217Yes
134CHAC2ChaC glutathione specific gamma-glutamylcyclotransferase 2 [Source:HGNC Symbol;Acc:HGNC:32363]33582-1.052-0.5179Yes
135ARL15ADP ribosylation factor like GTPase 15 [Source:HGNC Symbol;Acc:HGNC:25945]33617-1.063-0.5099Yes
136DCAF17DDB1 and CUL4 associated factor 17 [Source:HGNC Symbol;Acc:HGNC:25784]33881-1.144-0.5075Yes
137SUV39H2suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287]33910-1.157-0.4985Yes
138SOAT1sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]34092-1.225-0.4932Yes
139TTC14tetratricopeptide repeat domain 14 [Source:HGNC Symbol;Acc:HGNC:24697]34256-1.277-0.4869Yes
140RNF220ring finger protein 220 [Source:HGNC Symbol;Acc:HGNC:25552]34282-1.287-0.4768Yes
141ADAadenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]34405-1.338-0.4689Yes
142NID2nidogen 2 [Source:HGNC Symbol;Acc:HGNC:13389]34523-1.390-0.4604Yes
143B3GNT3UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:13528]34835-1.540-0.4559Yes
144MCM3minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945]34974-1.599-0.4463Yes
145CDCA7cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628]34990-1.606-0.4332Yes
146CPPED1calcineurin like phosphoesterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25632]35009-1.618-0.4202Yes
147GINS1GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980]35174-1.706-0.4103Yes
148PCpyruvate carboxylase [Source:HGNC Symbol;Acc:HGNC:8636]35412-1.861-0.4011Yes
149EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527]35424-1.868-0.3858Yes
150MCM4minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947]35527-1.929-0.3724Yes
151ATAD2ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123]35543-1.940-0.3565Yes
152NBEAL1neurobeachin like 1 [Source:HGNC Symbol;Acc:HGNC:20681]35624-2.002-0.3419Yes
153MCM5minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948]35798-2.127-0.3288Yes
154C1orf159chromosome 1 open reading frame 159 [Source:HGNC Symbol;Acc:HGNC:26062]35848-2.171-0.3119Yes
155LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560]35856-2.178-0.2939Yes
156TMOD1tropomodulin 1 [Source:HGNC Symbol;Acc:HGNC:11871]36083-2.362-0.2802Yes
157UHRF1ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556]36102-2.384-0.2607Yes
158RACGAP1Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]36268-2.566-0.2437Yes
159RCBTB2RCC1 and BTB domain containing protein 2 [Source:HGNC Symbol;Acc:HGNC:1914]36339-2.629-0.2236Yes
160NRP1neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004]36352-2.643-0.2017Yes
161UNC119unc-119 lipid binding chaperone [Source:HGNC Symbol;Acc:HGNC:12565]36376-2.674-0.1800Yes
162PKP2plakophilin 2 [Source:HGNC Symbol;Acc:HGNC:9024]36616-3.022-0.1611Yes
163RFTN1raftlin, lipid raft linker 1 [Source:HGNC Symbol;Acc:HGNC:30278]36679-3.129-0.1366Yes
164E2F8E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727]36682-3.139-0.1103Yes
165LIG1DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598]36746-3.284-0.0845Yes
166MAP3K6mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858]36853-3.536-0.0578Yes
167SCRN2secernin 2 [Source:HGNC Symbol;Acc:HGNC:30381]36871-3.592-0.0281Yes
168FRMD4BFERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]36998-4.0640.0025Yes
Table: GSEA details [plain text format]



Fig 2: SRC_UP.V1_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SRC_UP.V1_DN: Random ES distribution   
Gene set null distribution of ES for SRC_UP.V1_DN