GSEA Report for Dataset all

Enrichment in phenotype: DBT (8 samples)

• 24 / 50 gene sets are upregulated in phenotype DBT
• 15 gene sets are significant at FDR < 25%
• 10 gene sets are significantly enriched at nominal pvalue < 1%
• 12 gene sets are significantly enriched at nominal pvalue < 5%
• Snapshot of enrichment results
• Detailed enrichment results in html format
• Detailed enrichment results in TSV format (tab delimited text)
• Guide to interpret results

Enrichment in phenotype: SCR (4 samples)

• 26 / 50 gene sets are upregulated in phenotype SCR
• 17 gene sets are significantly enriched at FDR < 25%
• 10 gene sets are significantly enriched at nominal pvalue < 1%
• 15 gene sets are significantly enriched at nominal pvalue < 5%
• Snapshot of enrichment results
• Detailed enrichment results in html format
• Detailed enrichment results in TSV format (tab delimited text)
• Guide to interpret results

Dataset details

• The dataset has 35493 native features
• After collapsing features into gene symbols, there are: 31239 genes

Gene set details

• Gene set size filters (min=15, max=500) resulted in filtering out 0 / 50 gene sets
• The remaining 50 gene sets were used in the analysis
• List of gene sets used and their sizes (restricted to features in the specified dataset)

Gene markers for the DBT versus SCR comparison

• The dataset has 31239 features (genes)
• # of markers for phenotype DBT: 11084 (35.5% ) with correlation area 46.2%
• # of markers for phenotype SCR: 20155 (64.5% ) with correlation area 53.8%
• Detailed rank ordered gene list for all features in the dataset
• Heat map and gene list correlation profile for all features in the dataset

Global statistics and plots

• Plot of p-values vs. NES
• Global ES histogram

Other

• Parameters used for this analysis

Comments

• Timestamp used as random seed: 1702934893461

Citing GSEA and MSigDB

To cite your use of the GSEA software please reference the following:

• Subramanian, A., Tamayo, P., et al. (2005, PNAS).
• Mootha, V. K., Lindgren, C. M., et al. (2003, Nature Genetics).

For use of the Molecular Signatures Database (MSigDB), to cite please reference
one or more of the following as appropriate, along with the source for the gene set as listed on the gene set page:

• Liberzon A, et al. (Bioinformatics, 2011).
• Liberzon A, et al. (Cell Systems 2015).