Datasetall_collapsed_to_symbols.all_pheno_new.cls#DBT_versus_SCR
Phenotypeall_pheno_new.cls#DBT_versus_SCR
Upregulated in classDBT
GeneSetHALLMARK_NOTCH_SIGNALING
Enrichment Score (ES)0.46196443
Normalized Enrichment Score (NES)1.216488
Nominal p-value0.17380352
FDR q-value0.14216824
FWER p-Value0.667
Table: GSEA Results Summary



Fig 1: Enrichment plot: HALLMARK_NOTCH_SIGNALING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1Tcf7l2transcription factor 7 like 2, T cell specific, HMG box [Source:MGI Symbol;Acc:MGI:1202879]4461.5960.0644Yes
2Dll1delta like canonical Notch ligand 1 [Source:MGI Symbol;Acc:MGI:104659]4851.5490.1397Yes
3Arrb1arrestin, beta 1 [Source:MGI Symbol;Acc:MGI:99473]7211.3660.1996Yes
4Notch2notch 2 [Source:MGI Symbol;Acc:MGI:97364]10981.1780.2457Yes
5LfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:MGI Symbol;Acc:MGI:1095413]15401.0210.2819Yes
6Fzd1frizzled class receptor 1 [Source:MGI Symbol;Acc:MGI:1196625]18330.9470.3193Yes
7Psen2presenilin 2 [Source:MGI Symbol;Acc:MGI:109284]19440.9190.3611Yes
8Dtx2deltex 2, E3 ubiquitin ligase [Source:MGI Symbol;Acc:MGI:1921448]27850.7510.3713Yes
9Hes1hes family bHLH transcription factor 1 [Source:MGI Symbol;Acc:MGI:104853]28590.7390.4054Yes
10Jag1jagged 1 [Source:MGI Symbol;Acc:MGI:1095416]31760.6830.4290Yes
11Aph1aaph1 homolog A, gamma secretase subunit [Source:MGI Symbol;Acc:MGI:2385110]37000.6030.4419Yes
12Ppardperoxisome proliferator activator receptor delta [Source:MGI Symbol;Acc:MGI:101884]39450.5640.4620Yes
13St3gal6ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:MGI Symbol;Acc:MGI:1888707]48510.4750.4564No
14Notch1notch 1 [Source:MGI Symbol;Acc:MGI:97363]69590.2830.4028No
15Dtx1deltex 1, E3 ubiquitin ligase [Source:MGI Symbol;Acc:MGI:1352744]70200.2760.4145No
16Wnt5awingless-type MMTV integration site family, member 5A [Source:MGI Symbol;Acc:MGI:98958]74780.2440.4119No
17Psenenpresenilin enhancer gamma secretase subunit [Source:MGI Symbol;Acc:MGI:1913590]96450.1500.3499No
18Maml2mastermind like transcriptional coactivator 2 [Source:MGI Symbol;Acc:MGI:2389460]98050.1300.3512No
19Prkcaprotein kinase C, alpha [Source:MGI Symbol;Acc:MGI:97595]102940.0930.3402No
20Fzd5frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571]105740.0650.3344No
21Cul1cullin 1 [Source:MGI Symbol;Acc:MGI:1349658]106370.0580.3353No
22Wnt2wingless-type MMTV integration site family, member 2 [Source:MGI Symbol;Acc:MGI:98954]158510.0000.1683No
23Heylhairy/enhancer-of-split related with YRPW motif-like [Source:MGI Symbol;Acc:MGI:1860511]161390.0000.1591No
24Sap30sin3 associated polypeptide [Source:MGI Symbol;Acc:MGI:1929129]20981-0.0050.0042No
25Ccnd1cyclin D1 [Source:MGI Symbol;Acc:MGI:88313]21485-0.069-0.0085No
26Fzd7frizzled class receptor 7 [Source:MGI Symbol;Acc:MGI:108570]23176-0.213-0.0522No
27Kat2aK(lysine) acetyltransferase 2A [Source:MGI Symbol;Acc:MGI:1343101]23399-0.237-0.0476No
28Dtx4deltex 4, E3 ubiquitin ligase [Source:MGI Symbol;Acc:MGI:2672905]24465-0.340-0.0650No
29Rbx1ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829]25429-0.395-0.0763No
30Fbxw11F-box and WD-40 domain protein 11 [Source:MGI Symbol;Acc:MGI:2144023]28806-0.970-0.1367No
31Skp1S-phase kinase-associated protein 1 [Source:MGI Symbol;Acc:MGI:103575]29942-1.396-0.1041No
32Notch3notch 3 [Source:MGI Symbol;Acc:MGI:99460]31101-2.9510.0044No
Table: GSEA details [plain text format]



Fig 2: HALLMARK_NOTCH_SIGNALING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HALLMARK_NOTCH_SIGNALING: Random ES distribution   
Gene set null distribution of ES for HALLMARK_NOTCH_SIGNALING