Datasetall_collapsed_to_symbols.all_pheno_new.cls#DBT_versus_SCR
Phenotypeall_pheno_new.cls#DBT_versus_SCR
Upregulated in classSCR
GeneSetHALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY
Enrichment Score (ES)-0.44887203
Normalized Enrichment Score (NES)-1.1873614
Nominal p-value0.18575852
FDR q-value0.20953982
FWER p-Value0.991
Table: GSEA Results Summary



Fig 1: Enrichment plot: HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1Catcatalase [Source:MGI Symbol;Acc:MGI:88271]2391.8830.0493No
2Prnpprion protein [Source:MGI Symbol;Acc:MGI:97769]12031.1420.0530No
3Fesfeline sarcoma oncogene [Source:MGI Symbol;Acc:MGI:95514]20410.8980.0533No
4Ptpaprotein phosphatase 2 protein activator [Source:MGI Symbol;Acc:MGI:1346006]21150.8830.0777No
5Oxsr1oxidative-stress responsive 1 [Source:MGI Symbol;Acc:MGI:1917378]22050.8660.1010No
6Hhexhematopoietically expressed homeobox [Source:MGI Symbol;Acc:MGI:96086]22770.8520.1245No
7Sbno2strawberry notch 2 [Source:MGI Symbol;Acc:MGI:2448490]27480.7590.1324No
8Egln2egl-9 family hypoxia-inducible factor 2 [Source:MGI Symbol;Acc:MGI:1932287]36250.6130.1228No
9Mbpmyelin basic protein [Source:MGI Symbol;Acc:MGI:96925]38230.5820.1341No
10Scaf4SR-related CTD-associated factor 4 [Source:MGI Symbol;Acc:MGI:2146350]39550.5620.1470No
11Cdkn2dcyclin dependent kinase inhibitor 2D [Source:MGI Symbol;Acc:MGI:105387]51290.4420.1227No
12Gclmglutamate-cysteine ligase, modifier subunit [Source:MGI Symbol;Acc:MGI:104995]52340.4250.1323No
13Pdlim1PDZ and LIM domain 1 (elfin) [Source:MGI Symbol;Acc:MGI:1860611]66250.3130.0972No
14Msramethionine sulfoxide reductase A [Source:MGI Symbol;Acc:MGI:106916]69430.2850.0956No
15Txnrd2thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023]94880.1670.0191No
16Junbjun B proto-oncogene [Source:MGI Symbol;Acc:MGI:96647]96910.1440.0170No
17Txnrd1thioredoxin reductase 1 [Source:MGI Symbol;Acc:MGI:1354175]98000.1300.0175No
18Glrxglutaredoxin [Source:MGI Symbol;Acc:MGI:2135625]101220.1030.0103No
19Ndufs2NADH:ubiquinone oxidoreductase core subunit S2 [Source:MGI Symbol;Acc:MGI:2385112]109240.026-0.0146No
20Ercc2excision repair cross-complementing rodent repair deficiency, complementation group 2 [Source:MGI Symbol;Acc:MGI:95413]109880.017-0.0161No
21Prdx4peroxiredoxin 4 [Source:MGI Symbol;Acc:MGI:1859815]130590.000-0.0825No
22Prdx6peroxiredoxin 6 [Source:MGI Symbol;Acc:MGI:894320]21089-0.023-0.3392No
23Hmox2heme oxygenase 2 [Source:MGI Symbol;Acc:MGI:109373]21263-0.044-0.3434No
24Sod2superoxide dismutase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:98352]21816-0.099-0.3581No
25Abcc1ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:MGI Symbol;Acc:MGI:102676]22243-0.145-0.3674No
26Mpomyeloperoxidase [Source:MGI Symbol;Acc:MGI:97137]22816-0.171-0.3805No
27Ftl1ferritin light polypeptide 1 [Source:MGI Symbol;Acc:MGI:95589]23701-0.258-0.4011No
28Glrx2glutaredoxin 2 (thioltransferase) [Source:MGI Symbol;Acc:MGI:1916617]23773-0.264-0.3954No
29Srxn1sulfiredoxin 1 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:104971]23786-0.266-0.3877No
30Gpx3glutathione peroxidase 3 [Source:MGI Symbol;Acc:MGI:105102]25235-0.369-0.4230No
31Gsrglutathione reductase [Source:MGI Symbol;Acc:MGI:95804]25354-0.383-0.4152No
32Mgst1microsomal glutathione S-transferase 1 [Source:MGI Symbol;Acc:MGI:1913850]26406-0.496-0.4339Yes
33Nqo1NAD(P)H dehydrogenase, quinone 1 [Source:MGI Symbol;Acc:MGI:103187]26667-0.534-0.4261Yes
34Txn1thioredoxin 1 [Source:MGI Symbol;Acc:MGI:98874]27232-0.634-0.4250Yes
35Sod1superoxide dismutase 1, soluble [Source:MGI Symbol;Acc:MGI:98351]27540-0.679-0.4143Yes
36Prdx2peroxiredoxin 2 [Source:MGI Symbol;Acc:MGI:109486]27987-0.769-0.4053Yes
37Selenosselenoprotein S [Source:MGI Symbol;Acc:MGI:95994]28078-0.789-0.3843Yes
38Stk25serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699]28156-0.806-0.3624Yes
39Gpx4glutathione peroxidase 4 [Source:MGI Symbol;Acc:MGI:104767]28361-0.856-0.3431Yes
40Ipcef1interaction protein for cytohesin exchange factors 1 [Source:MGI Symbol;Acc:MGI:2444159]28632-0.926-0.3237Yes
41Lamtor5late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:MGI Symbol;Acc:MGI:1915826]29187-1.086-0.3087Yes
42Prdx1peroxiredoxin 1 [Source:MGI Symbol;Acc:MGI:99523]29206-1.092-0.2762Yes
43Ndufa6NADH:ubiquinone oxidoreductase subunit A6 [Source:MGI Symbol;Acc:MGI:1914380]29285-1.118-0.2449Yes
44Gclcglutamate-cysteine ligase, catalytic subunit [Source:MGI Symbol;Acc:MGI:104990]29506-1.204-0.2155Yes
45Atox1antioxidant 1 copper chaperone [Source:MGI Symbol;Acc:MGI:1333855]29771-1.315-0.1842Yes
46G6pdxglucose-6-phosphate dehydrogenase X-linked [Source:MGI Symbol;Acc:MGI:105979]30467-1.772-0.1529Yes
47Pfkpphosphofructokinase, platelet [Source:MGI Symbol;Acc:MGI:1891833]30778-2.141-0.0981Yes
48Lsp1lymphocyte specific 1 [Source:MGI Symbol;Acc:MGI:96832]31180-3.7290.0019Yes
Table: GSEA details [plain text format]



Fig 2: HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY: Random ES distribution   
Gene set null distribution of ES for HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY