Datasetall_collapsed_to_symbols.all_pheno_new.cls#DBT_versus_SCR
Phenotypeall_pheno_new.cls#DBT_versus_SCR
Upregulated in classSCR
GeneSetHALLMARK_XENOBIOTIC_METABOLISM
Enrichment Score (ES)-0.4609446
Normalized Enrichment Score (NES)-1.4421949
Nominal p-value0.0
FDR q-value0.028249197
FWER p-Value0.267
Table: GSEA Results Summary



Fig 1: Enrichment plot: HALLMARK_XENOBIOTIC_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FasFas (TNF receptor superfamily member 6) [Source:MGI Symbol;Acc:MGI:95484]2371.8900.0052No
2Catcatalase [Source:MGI Symbol;Acc:MGI:88271]2391.8830.0179No
3Ptgdsprostaglandin D2 synthase (brain) [Source:MGI Symbol;Acc:MGI:99261]3881.6670.0244No
4Acp2acid phosphatase 2, lysosomal [Source:MGI Symbol;Acc:MGI:87882]7501.3490.0219No
5Bcar1breast cancer anti-estrogen resistance 1 [Source:MGI Symbol;Acc:MGI:108091]8541.2940.0273No
6Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 1 [Source:MGI Symbol;Acc:MGI:88588]10391.2030.0295No
7Pdk4pyruvate dehydrogenase kinase, isoenzyme 4 [Source:MGI Symbol;Acc:MGI:1351481]10481.1960.0374No
8Cfbcomplement factor B [Source:MGI Symbol;Acc:MGI:105975]10501.1950.0454No
9Ephx1epoxide hydrolase 1, microsomal [Source:MGI Symbol;Acc:MGI:95405]10541.1940.0534No
10Cndp2CNDP dipeptidase 2 (metallopeptidase M20 family) [Source:MGI Symbol;Acc:MGI:1913304]10891.1800.0603No
11Gcnt2glucosaminyl (N-acetyl) transferase 2, I-branching enzyme [Source:MGI Symbol;Acc:MGI:1100870]11781.1510.0653No
12Serpine1serine (or cysteine) peptidase inhibitor, clade E, member 1 [Source:MGI Symbol;Acc:MGI:97608]12011.1420.0723No
13Hnf4ahepatic nuclear factor 4, alpha [Source:MGI Symbol;Acc:MGI:109128]12311.1300.0790No
14Pros1protein S (alpha) [Source:MGI Symbol;Acc:MGI:1095733]12511.1210.0860No
15Pcxpyruvate carboxylase [Source:MGI Symbol;Acc:MGI:97520]12921.1080.0922No
16Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [Source:MGI Symbol;Acc:MGI:1352447]14391.0550.0947No
17Npc1NPC intracellular cholesterol transporter 1 [Source:MGI Symbol;Acc:MGI:1097712]16001.0040.0963No
18Pmm1phosphomannomutase 1 [Source:MGI Symbol;Acc:MGI:1353418]16380.9930.1018No
19Igf1insulin-like growth factor 1 [Source:MGI Symbol;Acc:MGI:96432]18440.9450.1016No
20Lpin2lipin 2 [Source:MGI Symbol;Acc:MGI:1891341]19410.9200.1048No
21Tpst1protein-tyrosine sulfotransferase 1 [Source:MGI Symbol;Acc:MGI:1298231]19480.9170.1108No
22Slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 6 [Source:MGI Symbol;Acc:MGI:98488]19870.9100.1157No
23Xdhxanthine dehydrogenase [Source:MGI Symbol;Acc:MGI:98973]21210.8820.1174No
24Gckrglucokinase regulatory protein [Source:MGI Symbol;Acc:MGI:1096345]21310.8800.1231No
25Il1r1interleukin 1 receptor, type I [Source:MGI Symbol;Acc:MGI:96545]21480.8760.1285No
26Ddcdopa decarboxylase [Source:MGI Symbol;Acc:MGI:94876]23070.8460.1291No
27Arg2arginase type II [Source:MGI Symbol;Acc:MGI:1330806]23260.8430.1342No
28Lcatlecithin cholesterol acyltransferase [Source:MGI Symbol;Acc:MGI:96755]24390.8190.1362No
29Irf8interferon regulatory factor 8 [Source:MGI Symbol;Acc:MGI:96395]25490.7950.1380No
30Fbln1fibulin 1 [Source:MGI Symbol;Acc:MGI:95487]25630.7910.1430No
31Ndrg2N-myc downstream regulated gene 2 [Source:MGI Symbol;Acc:MGI:1352498]26710.7710.1448No
32Gstm4glutathione S-transferase, mu 4 [Source:MGI Symbol;Acc:MGI:95862]27290.7620.1481No
33Dhrs1dehydrogenase/reductase (SDR family) member 1 [Source:MGI Symbol;Acc:MGI:1196314]29790.7170.1449No
34Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Source:MGI Symbol;Acc:MGI:88110]29950.7160.1493No
35Arg1arginase, liver [Source:MGI Symbol;Acc:MGI:88070]30830.6950.1512No
36Smoxspermine oxidase [Source:MGI Symbol;Acc:MGI:2445356]34140.6540.1450No
37Gsto1glutathione S-transferase omega 1 [Source:MGI Symbol;Acc:MGI:1342273]35850.6200.1437No
38Ets2E26 avian leukemia oncogene 2, 3' domain [Source:MGI Symbol;Acc:MGI:95456]36030.6180.1473No
39Porcytochrome p450 oxidoreductase [Source:MGI Symbol;Acc:MGI:97744]38770.5750.1424No
40Ppardperoxisome proliferator activator receptor delta [Source:MGI Symbol;Acc:MGI:101884]39450.5640.1441No
41Man1amannosidase 1, alpha [Source:MGI Symbol;Acc:MGI:104677]49630.4610.1144No
42Papss23'-phosphoadenosine 5'-phosphosulfate synthase 2 [Source:MGI Symbol;Acc:MGI:1330223]50190.4530.1157No
43Slc12a4solute carrier family 12, member 4 [Source:MGI Symbol;Acc:MGI:1309465]51190.4430.1155No
44Tgfb2transforming growth factor, beta 2 [Source:MGI Symbol;Acc:MGI:98726]52370.4250.1147No
45Itih4inter alpha-trypsin inhibitor, heavy chain 4 [Source:MGI Symbol;Acc:MGI:109536]53150.4140.1150No
46Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 2 [Source:MGI Symbol;Acc:MGI:88589]62860.3530.0861No
47Gssglutathione synthetase [Source:MGI Symbol;Acc:MGI:95852]63130.3490.0876No
48Karslysyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1934754]64260.3370.0863No
49F11coagulation factor XI [Source:MGI Symbol;Acc:MGI:99481]68080.2970.0761No
50Leap2liver-expressed antimicrobial peptide 2 [Source:MGI Symbol;Acc:MGI:2672795]68200.2970.0777No
51Slc22a1solute carrier family 22 (organic cation transporter), member 1 [Source:MGI Symbol;Acc:MGI:108111]68410.2970.0791No
52Abcd2ATP-binding cassette, sub-family D (ALD), member 2 [Source:MGI Symbol;Acc:MGI:1349467]73790.2560.0635No
53Nfs1nitrogen fixation gene 1 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1316706]74090.2530.0643No
54Tmem176btransmembrane protein 176B [Source:MGI Symbol;Acc:MGI:1916348]74650.2460.0642No
55Comtcatechol-O-methyltransferase [Source:MGI Symbol;Acc:MGI:88470]75790.2390.0622No
56CrpC-reactive protein, pentraxin-related [Source:MGI Symbol;Acc:MGI:88512]75800.2390.0638No
57Igfbp1insulin-like growth factor binding protein 1 [Source:MGI Symbol;Acc:MGI:96436]83890.2260.0393No
58Pgrmc1progesterone receptor membrane component 1 [Source:MGI Symbol;Acc:MGI:1858305]89900.2150.0214No
59Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase [Source:MGI Symbol;Acc:MGI:1342005]93680.1810.0105No
60Aldh2aldehyde dehydrogenase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:99600]94690.1710.0084No
61Entpd5ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385]99880.119-0.0075No
62Abcc3ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:MGI Symbol;Acc:MGI:1923658]102860.094-0.0164No
63Fmo1flavin containing monooxygenase 1 [Source:MGI Symbol;Acc:MGI:1310002]103260.088-0.0170No
64Ssr3signal sequence receptor, gamma [Source:MGI Symbol;Acc:MGI:1914687]105500.068-0.0238No
65F10coagulation factor X [Source:MGI Symbol;Acc:MGI:103107]106130.062-0.0254No
66Alas1aminolevulinic acid synthase 1 [Source:MGI Symbol;Acc:MGI:87989]108820.032-0.0338No
67Sertad1SERTA domain containing 1 [Source:MGI Symbol;Acc:MGI:1913438]108850.031-0.0336No
68Acox3acyl-Coenzyme A oxidase 3, pristanoyl [Source:MGI Symbol;Acc:MGI:1933156]110360.009-0.0384No
69Ninj1ninjurin 1 [Source:MGI Symbol;Acc:MGI:1196617]110710.002-0.0395No
70Tdo2tryptophan 2,3-dioxygenase [Source:MGI Symbol;Acc:MGI:1928486]130570.000-0.1034No
71Acsm1acyl-CoA synthetase medium-chain family member 1 [Source:MGI Symbol;Acc:MGI:2152200]131050.000-0.1049No
72Itih1inter-alpha trypsin inhibitor, heavy chain 1 [Source:MGI Symbol;Acc:MGI:96618]135350.000-0.1188No
73Fabp1fatty acid binding protein 1, liver [Source:MGI Symbol;Acc:MGI:95479]137070.000-0.1243No
74Angptl3angiopoietin-like 3 [Source:MGI Symbol;Acc:MGI:1353627]141010.000-0.1369No
75Hrghistidine-rich glycoprotein [Source:MGI Symbol;Acc:MGI:2146636]147230.000-0.1569No
76Akr1c6aldo-keto reductase family 1, member C6 [Source:MGI Symbol;Acc:MGI:1933427]147560.000-0.1580No
77G6pcglucose-6-phosphatase, catalytic [Source:MGI Symbol;Acc:MGI:95607]148370.000-0.1605No
78Plgplasminogen [Source:MGI Symbol;Acc:MGI:97620]159110.000-0.1951No
79Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 6 [Source:MGI Symbol;Acc:MGI:88278]161650.000-0.2033No
80Tattyrosine aminotransferase [Source:MGI Symbol;Acc:MGI:98487]162300.000-0.2053No
81Fbp1fructose bisphosphatase 1 [Source:MGI Symbol;Acc:MGI:95492]164880.000-0.2136No
82Vtnvitronectin [Source:MGI Symbol;Acc:MGI:98940]165120.000-0.2143No
83Fmo3flavin containing monooxygenase 3 [Source:MGI Symbol;Acc:MGI:1100496]179090.000-0.2593No
84Mbl2mannose-binding lectin (protein C) 2 [Source:MGI Symbol;Acc:MGI:96924]180660.000-0.2643No
85Gad1glutamate decarboxylase 1 [Source:MGI Symbol;Acc:MGI:95632]183930.000-0.2748No
86Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 1 [Source:MGI Symbol;Acc:MGI:88586]197850.000-0.3196No
87Ttpatocopherol (alpha) transfer protein [Source:MGI Symbol;Acc:MGI:1354168]203230.000-0.3369No
88Upb1ureidopropionase, beta [Source:MGI Symbol;Acc:MGI:2143535]21098-0.024-0.3617No
89Abhd6abhydrolase domain containing 6 [Source:MGI Symbol;Acc:MGI:1913332]21132-0.028-0.3626No
90Gnmtglycine N-methyltransferase [Source:MGI Symbol;Acc:MGI:1202304]21362-0.052-0.3696No
91Cdo1cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925]21400-0.057-0.3704No
92Cyp2s1cytochrome P450, family 2, subfamily s, polypeptide 1 [Source:MGI Symbol;Acc:MGI:1921384]21593-0.078-0.3761No
93Tyrtyrosinase [Source:MGI Symbol;Acc:MGI:98880]21732-0.092-0.3799No
94Jupjunction plakoglobin [Source:MGI Symbol;Acc:MGI:96650]21870-0.105-0.3836No
95Tnfrsf1atumor necrosis factor receptor superfamily, member 1a [Source:MGI Symbol;Acc:MGI:1314884]22023-0.118-0.3877No
96Tmbim6transmembrane BAX inhibitor motif containing 6 [Source:MGI Symbol;Acc:MGI:99682]22188-0.139-0.3920No
97Kynukynureninase [Source:MGI Symbol;Acc:MGI:1918039]22585-0.146-0.4038No
98Etfdhelectron transferring flavoprotein, dehydrogenase [Source:MGI Symbol;Acc:MGI:106100]22687-0.157-0.4060No
99Hsd17b2hydroxysteroid (17-beta) dehydrogenase 2 [Source:MGI Symbol;Acc:MGI:1096386]22753-0.164-0.4070No
100Ahcyladenosylhomocysteinase like [Source:MGI Symbol;Acc:MGI:3643647]22792-0.169-0.4070No
101Acox1acyl-Coenzyme A oxidase 1, palmitoyl [Source:MGI Symbol;Acc:MGI:1330812]22897-0.177-0.4092No
102Aco2aconitase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:87880]23072-0.199-0.4135No
103Cyp4f14cytochrome P450, family 4, subfamily f, polypeptide 14 [Source:MGI Symbol;Acc:MGI:1927669]23224-0.218-0.4168No
104Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast) [Source:MGI Symbol;Acc:MGI:1916051]23296-0.226-0.4176No
105Maoamonoamine oxidase A [Source:MGI Symbol;Acc:MGI:96915]23311-0.227-0.4165No
106Atoh8atonal bHLH transcription factor 8 [Source:MGI Symbol;Acc:MGI:1918343]23339-0.230-0.4158No
107Hes6hairy and enhancer of split 6 [Source:MGI Symbol;Acc:MGI:1859852]23651-0.254-0.4241No
108Ptges3-psprostaglandin E synthase 3, pseudogene [Source:MGI Symbol;Acc:MGI:3704271]23845-0.274-0.4285No
109Arpp19cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691]23982-0.284-0.4309No
110Acp1acid phosphatase 1, soluble [Source:MGI Symbol;Acc:MGI:87881]24295-0.320-0.4388No
111Pdlim5PDZ and LIM domain 5 [Source:MGI Symbol;Acc:MGI:1927489]24353-0.327-0.4384No
112Idh1isocitrate dehydrogenase 1 (NADP+), soluble [Source:MGI Symbol;Acc:MGI:96413]24474-0.341-0.4400No
113Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 [Source:MGI Symbol;Acc:MGI:95628]24765-0.357-0.4469No
114Cyfip2cytoplasmic FMR1 interacting protein 2 [Source:MGI Symbol;Acc:MGI:1924134]25012-0.357-0.4524No
115Ces1dcarboxylesterase 1D [Source:MGI Symbol;Acc:MGI:2148202]25039-0.357-0.4509No
116Gartphosphoribosylglycinamide formyltransferase [Source:MGI Symbol;Acc:MGI:95654]25171-0.361-0.4526No
117Reg1regenerating islet-derived 1 [Source:MGI Symbol;Acc:MGI:97895]25267-0.372-0.4532No
118Cdacytidine deaminase [Source:MGI Symbol;Acc:MGI:1919519]25291-0.375-0.4514No
119Gsrglutathione reductase [Source:MGI Symbol;Acc:MGI:95804]25354-0.383-0.4508No
120Gch1GTP cyclohydrolase 1 [Source:MGI Symbol;Acc:MGI:95675]25409-0.392-0.4499No
121Marchf6membrane associated ring-CH-type finger 6 [Source:MGI Symbol;Acc:MGI:2442773]25466-0.400-0.4490No
122Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 1 [Source:MGI Symbol;Acc:MGI:88607]25839-0.426-0.4581Yes
123Epha2Eph receptor A2 [Source:MGI Symbol;Acc:MGI:95278]25907-0.434-0.4573Yes
124Slc35b1solute carrier family 35, member B1 [Source:MGI Symbol;Acc:MGI:1343133]25912-0.435-0.4545Yes
125Cyp2c55cytochrome P450, family 2, subfamily c, polypeptide 55 [Source:MGI Symbol;Acc:MGI:1919332]26096-0.458-0.4573Yes
126Fetubfetuin beta [Source:MGI Symbol;Acc:MGI:1890221]26172-0.467-0.4565Yes
127Ap4b1adaptor-related protein complex AP-4, beta 1 [Source:MGI Symbol;Acc:MGI:1337130]26281-0.477-0.4568Yes
128Apoeapolipoprotein E [Source:MGI Symbol;Acc:MGI:88057]26354-0.489-0.4558Yes
129Hmox1heme oxygenase 1 [Source:MGI Symbol;Acc:MGI:96163]26395-0.495-0.4537Yes
130Dhpsdeoxyhypusine synthase [Source:MGI Symbol;Acc:MGI:2683592]26438-0.500-0.4517Yes
131Gabarapl1gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 [Source:MGI Symbol;Acc:MGI:1914980]26488-0.507-0.4498Yes
132Tkfctriokinase, FMN cyclase [Source:MGI Symbol;Acc:MGI:2385084]26508-0.511-0.4470Yes
133Nqo1NAD(P)H dehydrogenase, quinone 1 [Source:MGI Symbol;Acc:MGI:103187]26667-0.534-0.4485Yes
134Cyp2j6cytochrome P450, family 2, subfamily j, polypeptide 6 [Source:MGI Symbol;Acc:MGI:1270148]26863-0.568-0.4509Yes
135Casp6caspase 6 [Source:MGI Symbol;Acc:MGI:1312921]26875-0.570-0.4474Yes
136Vnn1vanin 1 [Source:MGI Symbol;Acc:MGI:108395]27168-0.620-0.4526Yes
137Ptgr1prostaglandin reductase 1 [Source:MGI Symbol;Acc:MGI:1914353]27177-0.622-0.4486Yes
138Adh5alcohol dehydrogenase 5 (class III), chi polypeptide [Source:MGI Symbol;Acc:MGI:87929]27197-0.628-0.4450Yes
139Aslargininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084]27413-0.650-0.4475Yes
140Ccl25chemokine (C-C motif) ligand 25 [Source:MGI Symbol;Acc:MGI:1099448]27561-0.683-0.4476Yes
141Hsd11b1hydroxysteroid 11-beta dehydrogenase 1 [Source:MGI Symbol;Acc:MGI:103562]27617-0.698-0.4447Yes
142Aox1aldehyde oxidase 1 [Source:MGI Symbol;Acc:MGI:88035]27669-0.706-0.4416Yes
143Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide [Source:MGI Symbol;Acc:MGI:87926]27856-0.739-0.4425Yes
144Pink1PTEN induced putative kinase 1 [Source:MGI Symbol;Acc:MGI:1916193]27887-0.746-0.4385Yes
145Cyb5acytochrome b5 type A (microsomal) [Source:MGI Symbol;Acc:MGI:1926952]27935-0.755-0.4349Yes
146Spint2serine protease inhibitor, Kunitz type 2 [Source:MGI Symbol;Acc:MGI:1338031]27955-0.761-0.4303Yes
147Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 1 [Source:MGI Symbol;Acc:MGI:1096359]27962-0.763-0.4254Yes
148UgdhUDP-glucose dehydrogenase [Source:MGI Symbol;Acc:MGI:1306785]28002-0.772-0.4214Yes
149Retsatretinol saturase (all trans retinol 13,14 reductase) [Source:MGI Symbol;Acc:MGI:1914692]28114-0.798-0.4196Yes
150Crotcarnitine O-octanoyltransferase [Source:MGI Symbol;Acc:MGI:1921364]28157-0.806-0.4155Yes
151Gstt2glutathione S-transferase, theta 2 [Source:MGI Symbol;Acc:MGI:106188]28175-0.811-0.4105Yes
152Pgdphosphogluconate dehydrogenase [Source:MGI Symbol;Acc:MGI:97553]28209-0.818-0.4060Yes
153Csadcysteine sulfinic acid decarboxylase [Source:MGI Symbol;Acc:MGI:2180098]28456-0.877-0.4080Yes
154Hprthypoxanthine guanine phosphoribosyl transferase [Source:MGI Symbol;Acc:MGI:96217]28469-0.879-0.4025Yes
155Slc35d1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 [Source:MGI Symbol;Acc:MGI:2140361]28472-0.880-0.3966Yes
156Acox2acyl-Coenzyme A oxidase 2, branched chain [Source:MGI Symbol;Acc:MGI:1934852]28633-0.926-0.3955Yes
157Cd36CD36 molecule [Source:MGI Symbol;Acc:MGI:107899]28751-0.957-0.3927Yes
158Psmb10proteasome (prosome, macropain) subunit, beta type 10 [Source:MGI Symbol;Acc:MGI:1096380]28873-0.988-0.3900Yes
159Nmt1N-myristoyltransferase 1 [Source:MGI Symbol;Acc:MGI:102579]28911-1.000-0.3844Yes
160Car2carbonic anhydrase 2 [Source:MGI Symbol;Acc:MGI:88269]28961-1.017-0.3791Yes
161Blvrbbiliverdin reductase B (flavin reductase (NADPH)) [Source:MGI Symbol;Acc:MGI:2385271]29240-1.101-0.3806Yes
162Tmem97transmembrane protein 97 [Source:MGI Symbol;Acc:MGI:1916321]29355-1.141-0.3765Yes
163Aldh9a1aldehyde dehydrogenase 9, subfamily A1 [Source:MGI Symbol;Acc:MGI:1861622]29361-1.145-0.3689Yes
164Lonp1lon peptidase 1, mitochondrial [Source:MGI Symbol;Acc:MGI:1921392]29465-1.188-0.3642Yes
165Gclcglutamate-cysteine ligase, catalytic subunit [Source:MGI Symbol;Acc:MGI:104990]29506-1.204-0.3574Yes
166Hacl12-hydroxyacyl-CoA lyase 1 [Source:MGI Symbol;Acc:MGI:1929657]29548-1.220-0.3504Yes
167Igfbp4insulin-like growth factor binding protein 4 [Source:MGI Symbol;Acc:MGI:96439]29605-1.241-0.3438Yes
168Rbp4retinol binding protein 4, plasma [Source:MGI Symbol;Acc:MGI:97879]29667-1.268-0.3372Yes
169Ddah2dimethylarginine dimethylaminohydrolase 2 [Source:MGI Symbol;Acc:MGI:1859016]29672-1.270-0.3287Yes
170Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) [Source:MGI Symbol;Acc:MGI:1858257]29832-1.341-0.3248Yes
171Mccc2methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [Source:MGI Symbol;Acc:MGI:1925288]30089-1.481-0.3230Yes
172Slc46a3solute carrier family 46, member 3 [Source:MGI Symbol;Acc:MGI:1918956]30115-1.500-0.3136Yes
173Esr1estrogen receptor 1 (alpha) [Source:MGI Symbol;Acc:MGI:1352467]30131-1.510-0.3039Yes
174Hgfachepatocyte growth factor activator [Source:MGI Symbol;Acc:MGI:1859281]30165-1.532-0.2946Yes
175Id2inhibitor of DNA binding 2 [Source:MGI Symbol;Acc:MGI:96397]30185-1.546-0.2847Yes
176Aqp9aquaporin 9 [Source:MGI Symbol;Acc:MGI:1891066]30187-1.547-0.2743Yes
177Pemtphosphatidylethanolamine N-methyltransferase [Source:MGI Symbol;Acc:MGI:104535]30272-1.603-0.2662Yes
178Ech1enoyl coenzyme A hydratase 1, peroxisomal [Source:MGI Symbol;Acc:MGI:1858208]30334-1.652-0.2569Yes
179Cyp27a1cytochrome P450, family 27, subfamily a, polypeptide 1 [Source:MGI Symbol;Acc:MGI:88594]30376-1.682-0.2469Yes
180Rap1gapRap1 GTPase-activating protein [Source:MGI Symbol;Acc:MGI:109338]30377-1.683-0.2355Yes
181Pts6-pyruvoyl-tetrahydropterin synthase [Source:MGI Symbol;Acc:MGI:1338783]30388-1.692-0.2244Yes
182Bphlbiphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen) [Source:MGI Symbol;Acc:MGI:1915271]30399-1.699-0.2132Yes
183DdtD-dopachrome tautomerase [Source:MGI Symbol;Acc:MGI:1298381]30473-1.775-0.2035Yes
184Fahfumarylacetoacetate hydrolase [Source:MGI Symbol;Acc:MGI:95482]30493-1.795-0.1920Yes
185Dcxrdicarbonyl L-xylulose reductase [Source:MGI Symbol;Acc:MGI:1915130]30599-1.918-0.1824Yes
186Sar1bsecretion associated Ras related GTPase 1B [Source:MGI Symbol;Acc:MGI:1913647]30612-1.928-0.1697Yes
187Shmt2serine hydroxymethyltransferase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1277989]30841-2.233-0.1619Yes
188Bcat1branched chain aminotransferase 1, cytosolic [Source:MGI Symbol;Acc:MGI:104861]30921-2.383-0.1484Yes
189Cbr1carbonyl reductase 1 [Source:MGI Symbol;Acc:MGI:88284]30982-2.536-0.1331Yes
190Upp1uridine phosphorylase 1 [Source:MGI Symbol;Acc:MGI:1097668]31030-2.687-0.1164Yes
191Slc1a5solute carrier family 1 (neutral amino acid transporter), member 5 [Source:MGI Symbol;Acc:MGI:105305]31047-2.751-0.0983Yes
192Dhrs7dehydrogenase/reductase (SDR family) member 7 [Source:MGI Symbol;Acc:MGI:1913625]31093-2.921-0.0800Yes
193Enpepglutamyl aminopeptidase [Source:MGI Symbol;Acc:MGI:106645]31107-2.966-0.0604Yes
194Ptgesprostaglandin E synthase [Source:MGI Symbol;Acc:MGI:1927593]31113-2.982-0.0403Yes
195Aldh3a1aldehyde dehydrogenase family 3, subfamily A1 [Source:MGI Symbol;Acc:MGI:1353451]31130-3.120-0.0197Yes
196Pycr1pyrroline-5-carboxylate reductase 1 [Source:MGI Symbol;Acc:MGI:2384795]31161-3.4230.0025Yes
Table: GSEA details [plain text format]



Fig 2: HALLMARK_XENOBIOTIC_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HALLMARK_XENOBIOTIC_METABOLISM: Random ES distribution   
Gene set null distribution of ES for HALLMARK_XENOBIOTIC_METABOLISM